Interleukins Activators

Cat.No.	Product Name	Information	Product Use Citations
E2502	Tamarixetin	Tamarixetin (4'-O-Methyl Quercetin) is a natural flavonoid derivative of quercetin and has superior anti-inflammatory properties in bacterial sepsis by increasing the population of IL-10-secreting immune cells.
S1709	17β-Estradiol	Estradiol (17β-estradiol, β-Estradiol, E2, 17β-Oestradiol) is a human sex hormone and steroid, and the primary female sex hormone. Estradiol upregulates IL-6 expression through the estrogen receptor β (ERβ) pathway.	Cancer Cell, 2025, 43(5):891-904.e10 Nat Commun, 2025, 16(1):758 Cell Rep Med, 2025, 6(7):102192
S2979	CU-T12-9	CU-T12-9 is a specific agonist of Toll-like receptor (TLR) 1/2 with EC50 of 52.9 nM in HEK-Blue hTLR2 SEAP assay. This compound activates both the innate and the adaptive immune systems. It signals through NF-κB and invokes an elevation of the downstream effectors TNF-α, IL-10, and iNOS.	Nat Commun, 2025, 16(1):2743 Biomedicine & Pharmacotherapy, 2023, 114638 Biomed Pharmacother, 2023, 162:114638
S0771	BRD6989	BRD6989 is a selective inhibitor of CDK8 and CDK19. This compound upregulates IL-10. It is an analog of the natural product cortistatin A (dCA).	Infect Drug Resist, 2021, 14:3135-3143
S0094	SR 0987	SR 0987, a SR 1078 analog, is an agonist for T cell-specific RORγ (RORγt) with EC50 of 800 nM. This compound represses PD-1, produces IL17 and is potential for the treatment of cancer.	Evid Based Complement Alternat Med, 2022, 2022:8315503.