| S8317 |
3BDO
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3BDO, a butyrolactone derivative, could target FKBP1A and activate the mTOR signaling pathway. It inhibits autophagy in HUVECs. This compound inhibits oxLDL-induced apoptosis.
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Cancer Immunology Research, May 02 2024, 631-643
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Journal of Neuroscience, July 15 2020, 5531-5548
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Cancer Immunology Research, 2024, 631–643
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| S7091 |
Zotarolimus (ABT-578)
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Zotarolimus (ABT-578, A 179578), an analogue of rapamycin, inhibits FKBP-12 binding with an IC50 of 2.8 nM.
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PLOS Biology, May 21, 2019, e3000252
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Pharmaceutical Chemistry Journal, March 2019, 1011–1015
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Molecules, 2023, 28(6)2820
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