FKBP Inhibitors

Cat.No. Product Name Information Product Use Citations Product Validations
S8317 3BDO 3BDO, a butyrolactone derivative, could target FKBP1A and activate the mTOR signaling pathway. It inhibits autophagy in HUVECs. This compound inhibits oxLDL-induced apoptosis.
Cancer Immunology Research, May 02 2024, 631-643
Journal of Neuroscience, July 15 2020, 5531-5548
Cancer Immunology Research, 2024, 631–643
S7091 Zotarolimus (ABT-578) Zotarolimus (ABT-578, A 179578), an analogue of rapamycin, inhibits FKBP-12 binding with an IC50 of 2.8 nM.
PLOS Biology, May 21, 2019, e3000252
Pharmaceutical Chemistry Journal, March 2019, 1011–1015
Molecules, 2023, 28(6)2820