FKBP Activators

Featured Inhibitors
Inhibitors (4)
Modulators (2)
Activators (2)
Antagonist (1)

Cat.No.	Product Name	Information	Product Use Citations	Product Validations
S9726	Rimiducid (AP1903)	Rimiducid (AP1903) is a chemical protein dimerizer that binds tightly to the target FKBP fusion protein while binding minimally to the abundant natural FKBP. This compound elicits potent and dose-dependent apoptosis of cells in culture expressing dimerizer-dependent Fas constructs, with an EC50 of ≈0.1 nM.
S8317	3BDO	3BDO, a butyrolactone derivative, could target FKBP1A and activate the mTOR signaling pathway. It inhibits autophagy in HUVECs. This compound inhibits oxLDL-induced apoptosis.	NPJ Parkinsons Dis, 2024, 10(1):52 Adv Sci (Weinh), 2023, 10(13):e2205436 Research Square, 2023, 10.21203/rs.3.rs-3629594/v1

Cat.No.

Product Name

Information

Product Use Citations

Product Validations

S9726

Rimiducid (AP1903)

Rimiducid (AP1903) is a chemical protein dimerizer that binds tightly to the target FKBP fusion protein while binding minimally to the abundant natural FKBP. This compound elicits potent and dose-dependent apoptosis of cells in culture expressing dimerizer-dependent Fas constructs, with an EC50 of ≈0.1 nM.

S8317

3BDO

3BDO, a butyrolactone derivative, could target FKBP1A and activate the mTOR signaling pathway. It inhibits autophagy in HUVECs. This compound inhibits oxLDL-induced apoptosis.

NPJ Parkinsons Dis, 2024, 10(1):52

Adv Sci (Weinh), 2023, 10(13):e2205436

Research Square, 2023, 10.21203/rs.3.rs-3629594/v1