BACE Inhibitors

Cat.No.	Product Name	Information
S3835	Loganin	Loganin (Loganoside) is an iridoid glycoside first isolated from the seeds of Strychnos nux-vomica, a member of the Loganiaceae family. This compound is a non-competitive inhibitor of BACE1 with IC50 of 47.97 μM an also inhibits AChE and BChE with IC50 values of 3.95 μM and 33.02 μM, respectively.
E2719^New	Dieckol	Dieckol is a marine-derived phlorotannin isolated from the brown alga Ecklonia cava, and exhibits potent dual inhibitory activity against β-secretase (BACE1) and acetylcholinesterase (AChE), with an IC50 of 2.34 μM (BACE1) and 5.69 μM (AChE), respectively.
S3245	Nodakenetin	Nodakenetin (NANI), a plant-derived coumarin isolated from Angelica decursiva, inhibits α-glucosidase, PTP1B, rat lens aldose reductase (RLAR), AChE, BChE, and β-site amyloid precursor protein cleaving enzyme 1 (BACE1). This compound alters the protein expression of Bax and Bcl-2, and prompts mitochondrial apoptosis. It exhibits anti-tumor activity.
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