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Trastuzumab-deruxtecan (DS-8201a, T-DXd)
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Trastuzumab deruxtecan (DS-8201a, T-DXd) is an antibody-drug conjugate (ADC) composed of an anti-HER2 (human epidermal growth factor receptor 2) antibody and a cytotoxic topoisomerase I inhibitor. Trastuzumab deruxtecan shows durable antitumor activity. Trastuzumab deruxtecan has a molecular weight of 153KDa. This product is supplied as 10mg/ml PBS solution.This product is discontinued. We recommend the replacement products: D4001.
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Proceedings of the National Academy of Sciences, May 6, 2024, e2322688121
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JCI Insight, 2025, 10(16)e187151
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