Adenylyl Cyclase

GPCR & G Protein

CGRP Receptor Endothelin Receptor S1P Receptor Cannabinoid Receptor Hedgehog/Smoothened SGLT Opioid Receptor GPR CCR MT Receptor PAFR OX Receptor PKA CaSR cAMP Vasopressin Receptor Protease-activated Receptor Adenosine Receptor Glucagon Receptor TAAR GRK AdipoR Prostaglandin Receptor CCK receptor GHSR Guanylate Cyclase GPCR19 GPR139 NPY receptor PAR TAS1R Sigma Receptor RGS Imidazoline Receptor Angiotensin Receptor PKG Neurokinin Receptor FPR DOCK Taste Receptor Melanocortin Receptor Somatostatin Receptor Bombesin Receptor Bradykinin Receptor CRFR GNRH Receptor TSH Receptor Parathyroid Hormone Receptor GLP-1 Receptor Adenylyl Cyclase Apelin receptor Arrestin GTPase MCHR Orphan Receptor Oxytocin Receptor Platelet aggregation RXFP receptor

All (5)
Adenylyl Cyclase Inhibitors (3)
Adenylyl Cyclase Activator (1)
Adenylyl Cyclase Agonist (1)
New Adenylyl Cyclase Products

Cat.No.	Product Name	Information	Product Use Citations
S2449	Forskolin (Colforsin)	Forskolin (Colforsin) is a ubiquitous activator of eukaryotic adenylyl cyclase (AC) in a wide variety of cell types, commonly used to raise levels of cAMP in the study and research of cell physiology. Forskolin also activates PXR and FXR activity. Forskolin stimulates autophagy.	Cell Host Microbe, 2025, 33(3):408-419.e8 Gut, 2025, gutjnl-2025-336105 Cell Stem Cell, 2025, S1934-5909(25)00265-6
E7446	NKY80	NKY80 is a potent, selective and non-competitive adenylyl cyclase (AC) type V isoform inhibitor with IC50s of 8.3 µM, 132 µM and 1.7 mM for type V, III and II, respectively. NKY80 is a non-nucleoside quinazolinone and regulates the AC catalytic activity in heart and lung tissues.
E8155^New	α-MSH	α-MSH (α-Melanocyte-Stimulating Hormone) is an endogenous neuropeptide and an agonist melanocortin-4 receptor (MC4R). It demonstrates anti-inflammatory, antipyretic activities, staphylocidal activity and also exhibits strong and rapid antimicrobial activity.
S0451	ST034307	ST034307 is a potent and selective inhibitor of adenylyl cyclase 1 (AC1) with IC50 of 2.3 μM.
E7528	2',5'-Dideoxyadenosine	2',5'-Dideoxyadenosine is a potent and non-competitive adenylyl cyclase inhibitor via binding the P-site with an IC50 of 3 µM . 2',5'-Dideoxyadenosine is a nucleoside analog and exerts a potent antiadrenergic action in heart.
E7446	NKY80	NKY80 is a potent, selective and non-competitive adenylyl cyclase (AC) type V isoform inhibitor with IC50s of 8.3 µM, 132 µM and 1.7 mM for type V, III and II, respectively. NKY80 is a non-nucleoside quinazolinone and regulates the AC catalytic activity in heart and lung tissues.
S0451	ST034307	ST034307 is a potent and selective inhibitor of adenylyl cyclase 1 (AC1) with IC50 of 2.3 μM.
E7528	2',5'-Dideoxyadenosine	2',5'-Dideoxyadenosine is a potent and non-competitive adenylyl cyclase inhibitor via binding the P-site with an IC50 of 3 µM . 2',5'-Dideoxyadenosine is a nucleoside analog and exerts a potent antiadrenergic action in heart.
S2449	Forskolin (Colforsin)	Forskolin (Colforsin) is a ubiquitous activator of eukaryotic adenylyl cyclase (AC) in a wide variety of cell types, commonly used to raise levels of cAMP in the study and research of cell physiology. Forskolin also activates PXR and FXR activity. Forskolin stimulates autophagy.	Cell Host Microbe, 2025, 33(3):408-419.e8 Gut, 2025, gutjnl-2025-336105 Cell Stem Cell, 2025, S1934-5909(25)00265-6
E8155^New	α-MSH	α-MSH (α-Melanocyte-Stimulating Hormone) is an endogenous neuropeptide and an agonist melanocortin-4 receptor (MC4R). It demonstrates anti-inflammatory, antipyretic activities, staphylocidal activity and also exhibits strong and rapid antimicrobial activity.
E8155^New	α-MSH	α-MSH (α-Melanocyte-Stimulating Hormone) is an endogenous neuropeptide and an agonist melanocortin-4 receptor (MC4R). It demonstrates anti-inflammatory, antipyretic activities, staphylocidal activity and also exhibits strong and rapid antimicrobial activity.