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Adenylyl Cyclase

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Cat.No. Product Name Information Product Use Citations Product Validations
S2449 Forskolin (Colforsin) Forskolin (Colforsin) is a ubiquitous activator of eukaryotic adenylyl cyclase (AC) in a wide variety of cell types, commonly used to raise levels of cAMP in the study and research of cell physiology. Forskolin also activates PXR and FXR activity. Forskolin stimulates autophagy.
Cell Mol Gastroenterol Hepatol, 2026, 20(1):101640
Cell Host Microbe, 2025, 33(3):408-419.e8
Gut, 2025, gutjnl-2025-336105
Verified customer review of Forskolin (Colforsin)
E7446 NKY80 NKY80 is a potent, selective and non-competitive adenylyl cyclase (AC) type V isoform inhibitor with IC50s of 8.3 µM, 132 µM and 1.7 mM for type V, III and II, respectively. NKY80 is a non-nucleoside quinazolinone and regulates the AC catalytic activity in heart and lung tissues.
E7528 2',5'-Dideoxyadenosine 2',5'-Dideoxyadenosine is a potent and non-competitive adenylyl cyclase inhibitor via binding the P-site with an IC50 of 3 µM . 2',5'-Dideoxyadenosine is a nucleoside analog and exerts a potent antiadrenergic action in heart.
E8155 α-MSH α-MSH (α-Melanocyte-Stimulating Hormone) is an endogenous neuropeptide and an agonist melanocortin-4 receptor (MC4R). It demonstrates anti-inflammatory, antipyretic activities, staphylocidal activity and also exhibits strong and rapid antimicrobial activity.
S0451 ST034307 ST034307 is a potent and selective inhibitor of adenylyl cyclase 1 (AC1) with IC50 of 2.3 μM.