PAR Inhibitors

Cat.No. Product Name Information Product Use Citations Product Validations
E0341 IUN76750 IUN76750 is a PAR-2 signaling pathway inhibitor.
E7137 Protease-Activated Receptor-2, amide Protease-Activated Receptor-2, amide (SLIGKV-NH2) is an agonist of protease-activated receptor 2 (PAR2) with a Ki of 9.64 μM and an IC50 of 10.4 μM, corresponding to the tethered ligand exposed by trypsin cleavage of PAR-2.
S9916 SCH79797 dihydrochloride SCH79797 dihydrochloride is a highly potent, selective nonpeptide protease activated receptor 1 (PAR1) antagonist, which can inhibit binding of a high-affinity thrombin receptor-activating peptide to PAR1 with an IC50 of 70 nM.