PAR Agonists

Cat.No.	Product Name	Information	Product Use Citations
E7046	TRAP-6	TRAP-6 (PAR-1 agonist peptide) is a synthetic hexapeptide (SFLLRN) that acts as a agonist of PAR-1 (protease-activated receptor-1). It also activates GPR15 on T-cells, regulating immune responses by suppressing acute GvHD while maintaining GvT activity.	Cancers, 2022, 4134
E7294	TFLLR-NH2	TFLLR-NH2 is a selective and potent agonist of proteinase-activated receptor 1 (PAR1) with an EC50 of 1.9 μM. It has potential for researching early tumor metastasis and supports early antiplatelet therapy to suppress colorectal cancer spread and improve survival rates.
E7137	Protease-Activated Receptor-2, amide	Protease-Activated Receptor-2, amide (SLIGKV-NH2) is an agonist of protease-activated receptor 2 (PAR2) with a Ki of 9.64 μM and an IC50 of 10.4 μM, corresponding to the tethered ligand exposed by trypsin cleavage of PAR-2.