| S2053 |
Cytidine
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Cytidine is a nucleoside molecule that is formed when cytosine is attached to a ribose ring, cytidine is a component of RNA.
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Nat Commun, 2025, 16(1):4451
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Virology, 2025, 610:110598
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Cancer Res, 2022, canres.1707.2021
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| S2439 |
Guanosine
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Guanosine is a purine nucleoside comprising guanine attached to a ribose (ribofuranose) ring via a β-N9-glycosidic bond.
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Nat Commun, 2022, 13(1):5845
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Cancer Res, 2022, canres.1707.2021
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Nat Commun, 2020, 11(1):6339
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| S3702 |
Dihydrothymine
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Dihydrothymine is an intermediate breakdown product of thymine.
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Cell Death Differ, 2019, 26(11):2223-2236
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Cell Death & Differentiation, 2019, 2223-2236
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| S6854 |
Triazavirin (TZV)
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Triazavirin (TZV) is a novel antiviral drug, a nucleoside analogue of nucleic acid that inhibits the synthesis of viral RNA and DNA and replication of genomic fragments. It is active against influenza and a number of other viruses, and is an effective protective agent on the transmission stage of influenza.
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Nature, 2022, 604(7904):120-126
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| E2919 |
5-Chloro-2'-deoxyuridine
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5-chloro-2′-deoxyuridine (5-chlorodeoxyuridine; CldU), a thymine analog, is used to study the potential of hypochlorous acid damage to DNA and DNA precursors.
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| S6138 |
5-Methylcytidine
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5-Methylcytidine is a modified nucleoside derived from 5-methylcytosine. It is found in ribonucleic acids of animal, plant, and bacterial origin.
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| S1714 |
Gemcitabine
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Gemcitabine, a nucleic acid synthesis inhibitor, is a very potent and specific deoxycytidine analogue, used as chemotherapy. Gemcitabine induces a potent p53-dependent apoptosis.
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Nature, 2025, 10.1038/s41586-025-08974-4
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Cell, 2025, S0092-8674(25)00556-2
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Cancer Cell, 2025, 43(8):1530-1548.e9
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| S1782 |
5-Azacytidine (5-Aza, Azacitidine)
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Azacitidine (5-Azacytidine, 5-AzaC, Ladakamycin, AZA, 5-Aza, CC-486,NSC 102816) is a nucleoside analogue of cytidine that specifically inhibits DNA methylation by trapping DNA methyltransferases. Azacitidine induces mitochondrial apoptosis and autophagy.
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Mol Cancer, 2025, 24(1):154
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Cell Rep Med, 2025, S2666-3791(25)00102-8
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Cell Rep Med, 2025, 6(12):102461
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| S1647 |
Adenosine
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Adenosine is a nucleoside composed of a molecule of adenine attached to a ribose sugar molecule (ribofuranose) moiety via a β-N9-glycosidic bond.
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Cancer Cell, 2025, 43(4):776-796.e14
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J Infect, 2025, 90(4):106449
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Nat Commun, 2025, 16(1):10378
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