(-)-p-Bromotetramisole Oxalate

Catalog No.S7383

(-)-p-Bromotetramisole Oxalate is a potent and non-specific alkaline phosphatase inhibitor.

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(-)-p-Bromotetramisole Oxalate Chemical Structure

(-)-p-Bromotetramisole Oxalate Chemical Structure
Molecular Weight: 373.22

Validation & Quality Control

Quality Control & MSDS

Product Information

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Product Description

Biological Activity

Description (-)-p-Bromotetramisole Oxalate is a potent and non-specific alkaline phosphatase inhibitor.
In vitro
In vivo
Features

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)

SpeciesMouseRatRabbitGuinea pigHamsterDog
Weight (kg)0.020.151.80.40.0810
Body Surface Area (m2)0.0070.0250.150.050.020.5
Km factor36128520
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Rat dose (mg/kg) = mouse dose (22.4 mg/kg) ×  mouse Km(3)  = 11.2 mg/kg
rat Km(6)
1

References

Chemical Information

Download (-)-p-Bromotetramisole Oxalate SDF
Molecular Weight (MW) 373.22
Formula

C13H13BrN2O4S

CAS No. 62284-79-1
Storage 3 years -20℃powder
2 years -80℃in solvent
Synonyms L-p-Bromotetramisole Oxalate
Solubility (25°C) * In vitro DMSO 74 mg/mL (198.27 mM)
Water 30 mg/mL warming (80.38 mM)
Ethanol <1 mg/mL
In vivo
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Chemical Name 6-(4-Bromophenyl)-2,3,5,6-tetrahydro-(6S)-imidazo[2,1-b]thiazole,ethanedioate (1:1)

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

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