Trk receptor Agonists

Featured Inhibitors
Inhibitors (19)
Agonists (3)
Activator (1)
Antagonist (1)

Cat.No.	Product Name	Information	Product Use Citations
S8319	7,8-Dihydroxyflavone	7,8-Dihydroxyflavone (7,8-DHF) acts as a potent and selective small-molecule agonist of the TrkB receptor (Kd ≈ 320 nM), the main signaling receptor of brain-derived neurotrophic factor (BDNF).	Int J Biol Sci, 2023, 19(16):5204-5217 Pharmacol Res, 2022, 176:106079 Int J Mol Sci, 2022, 23(24)16205
S2985	N-Acetyl-5-hydroxytryptamine	N-Acetyl-5-hydroxytryptamine (NAS, N-Acetylserotonin, Normelatonin, O-Demethylmelatonin), a precursor of melatonin, is a potent and selective agonist of TrkB receptor.	iScience, 2023, 26(3):106241
S0827	LM22A-4	LM22A-4 (LM 22A4) is a specific agonist of tyrosine kinase receptor B (TrkB) that reduces the development of tissue injury associated with spinal cord trauma.

Cat.No.

Product Name

Information

Product Use Citations

Product Validations

S8319

7,8-Dihydroxyflavone

7,8-Dihydroxyflavone (7,8-DHF) acts as a potent and selective small-molecule agonist of the TrkB receptor (Kd ≈ 320 nM), the main signaling receptor of brain-derived neurotrophic factor (BDNF).

Int J Biol Sci, 2023, 19(16):5204-5217

Pharmacol Res, 2022, 176:106079

Int J Mol Sci, 2022, 23(24)16205

S2985

N-Acetyl-5-hydroxytryptamine

N-Acetyl-5-hydroxytryptamine (NAS, N-Acetylserotonin, Normelatonin, O-Demethylmelatonin), a precursor of melatonin, is a potent and selective agonist of TrkB receptor.

iScience, 2023, 26(3):106241

S0827

LM22A-4

LM22A-4 (LM 22A4) is a specific agonist of tyrosine kinase receptor B (TrkB) that reduces the development of tissue injury associated with spinal cord trauma.