|Catalog No.||Product Name||Information||Selective / Pan||IC50 / Ki|
LY2109761 is a novel selective TGF-β receptor type I/II (TβRI/II) dual inhibitor with Ki of 38 nM and 300 nM, respectively; shown to negatively affect the phosphorylation of Smad2.
|Pan||TβRII, Ki: 300 nM|
LY364947 is a potent ATP-competitive inhibitor of TGFβR-I with IC50 of 59 nM, shows 7-fold selectivity over TGFβR-II.
|Pan||TGFβRII, IC50: 0.4 μM|
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