Home Metabolism ROR RORalpha Selective Agonists

RORalpha Selective Agonists

  • RORα
  • RORγ
Catalog No. Product Name Information Selective / Pan IC50 / Ki
S2654 Neoruscogenin Neoruscogenin, a natural sapogenin isolated from R. rhizoma, is a potent and high-affinity agonist of RAR-related orphan receptor alpha (RORα or nuclear receptor NR1F1). Selective
S2969 SR3335 SR3335 (ML-176) is a selective and inverse agonist of retinoic acid receptor-related receptor α (RORα) that directly binds to RORα with Ki of 220 nM. Selective RORα, Ki: 220 nM
S5775 SR1078 SR1078, a synthetic ligand for RORα and RORγ, functions as a RORα/γ agonist. Pan
S6724 SR1001 SR1001 is a RORα inverse agonist with Ki values of 172 nM and 111 nM for RORα and RORγ respectively. Pan RORα, Ki: 172 nM