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PD-1/PD-L1 interaction Selective Inhibitors

  • PD-1/PD-L1 interaction
  • PD-1
  • PD-L1
Catalog No. Product Name Information Selective / Pan IC50 / Ki
S8859 BMS-1166 BMS-1166 is a novel and potent small molecule inhibitor of the PD-1/PD-L1 interaction with an IC50 of 1.4 nM. Selective PD-1/PD-L1 interaction, IC50: 1.4 nM
S8158 PD-1/PD-L1 Inhibitor 3 PD-1/PD-L1 Inhibitor 3（Programmed Death-1/Programmed Death-Ligand 1 Inhibitor 3）is a Macrocyclic inhibitor of PD-1/PD-L1 interaction with IC50 of 5.6 nM Selective PD-1/PD-L1 interaction, IC50: 5.6 nM
S7911 BMS-1 BMS-1 is a small-molecule inhibitor of PD-1/PD-L1 interaction with IC50 of 6 nM. Selective PD-1/PD-L1 interaction, IC50: 0.006 μM
S9863 INCB086550 INCB086550 (PD-1/PD-L1-IN-8) is a potent PD-1/PD-L1 inhibitor, with an IC50 <= 10 nM. Selective PD-1/PD-L1, IC50: <10 nM
S7912 BMS202 BMS202 is a small-molecule PD-1/PD-L1 interaction inhibitor with IC50 of 18 nM. Selective PD-1/PD-L1 interaction, IC50: 0.018 μM
S9610 BMS-1001 BMS-1001 is a potent inhibitor of PD-1/PD-L1 interaction with EC50 of 253 nM. BMS-1001 alleviates the inhibitory effect of the soluble PD-L1 on the T-cell receptor-mediated activation of T-lymphocytes. Selective PD-1/PD-L1, EC50: 253 nM