For research use only. Not for use in humans.

Upifitamab (Anti-SLC34A2)

Synonyms: null Cat.No.A2351 Purity:99%

Upifitamab (Anti-SLC34A2) is a humanized monoclonal antibody targeting NaPi2b. Upifitamab can be used to synthesize an ADC compound, Upifitamab rilsodotin, used in ovarian cancer research, particularly in platinum-resistant recurrent ovarian cancer. MW : 145.5 KD.

Quality Control

Batch: A235101 Purity: 99% Protein concentration: 7.667mg/ml Endotoxin Level: ＜1EU/mg

Cited in Nature Medicine for its top-tier quality
COA
SDS
Datasheet

Specificity

Name	Citation	Sodium Channel	Others
A-803467	2	+++
Camostat Mesilate	16	+++
Ambroxol HCl	0	++
Flecainide hydrochloride	0	++++
Suzetrigine (VX-548)	0	++++
Tenapanor	0	++++
SEA0400	0	+++	ROS,ERK,p38 MAPK
SLC13A5-IN-1	0	+++
LTGO-33	0	✔
EIPA (L593754)	8	✔
Vernakalant (RSD1235) Hydrochloride	0	✔
QX-314 chloride	0	✔
VX-150	0	✔
Rimeporide	0	✔
(-)-Sparteine Sulfate	0	✔
Benzocaine	0	✔
Tolperisone HCl	1	✔
Vinpocetine	1	✔

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1. "+" indicates inhibitory effect. Increased inhibition is marked by a higher "+" designation. 2. "✔" indicates inhibitory effect, but without specific value.

Mechanism of Action

Description	Upifitamab (Anti-SLC34A2) is a humanized monoclonal antibody targeting NaPi2b. Upifitamab can be used to synthesize an ADC compound, Upifitamab rilsodotin, used in ovarian cancer research, particularly in platinum-resistant recurrent ovarian cancer. MW : 145.5 KD.

Cell Lines	Assay Type	Concentration	Incubation Time	Formulation	Activity Description	PMID

Product Details

CAS No.	2254118-43-7
Molecular Weight	145.5 kDa
Isotype	Human IgG1
Source	CHO
Purification	AKTA
Sterility	0.2 μM filtered
Formulation	100 mM Pro-Ac, 20mM Arg, pH5.0
Storage (From the date of receipt)	Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.

Comparison of Clones for

^*Literature analysis of various clone (for this target) products available on the market shows that Selleck's selected clones are more frequently applied. (data until September 2024)

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