Molecular Weight: 392.4 g/mol
Chemical Structure
Check the
SN-38
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
19 mg/mL
(48.41 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
| DMSO |
50 mg/mL
(127.42 mM)
; Warmed with 60°C water bath
; Ultrasonicated
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
| DMSO |
40 mg/mL
(101.93 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
| DMSO |
20 mg/mL
(50.96 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
| DMSO |
50 mg/mL
(127.42 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Pre-aliquoted for Longevity: Solid-state aliquots offer significantly longer shelf life compared to stock solutions, ensuring maximum stability for every use.
Looking for a specific aliquot size? Reach out to your local sales representative or contact us at orders@selleckchem.com.
| IUPAC Name | (19S)-10,19-diethyl-7,19-dihydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4(9),5,7,10,15(20)-heptaene-14,18-dione | |
|---|---|---|
| CAS Number | 86639-52-3 | |
| Molecular Formula |
C22H20N2O5 |
|
| Molecular Weight (MW) | 392.4 | |
| SMILES | CCC1=C2CN3C(=CC4=C(C3=O)COC(=O)C4(CC)O)C2=NC5=C1C=C(C=C5)O | |
| InChIKey | FJHBVJOVLFPMQE-QFIPXVFZSA-N |
- SN-38 Mechanism of Action: Topoisomerase I Inhibition in Cancer Cell Research
- SN-38 Clinical Trials
- SN-38 Working Concentration | Cell Culture | Treatment
- SN-38 Solubility in DMSO
- SN-38 Stock Solution
- SN-38 Storage
- SN-38 Stability
- SN-38 Combination Database
- SN-38 SMILES
- SN-38 CAS Number
- SN-38 Chemical Structure (2D and 3D)
- SN-38 IC50 for Cell-based and Cell-free Assays
- SN-38 Sigma (H0165)? Try a better option.
- SN-38 APExBIO (N2133)? Try a better option.
- SN-38 Cayman (15632)? Try a better option.
- SN-38 MedChemExpress (HY-13704)? Try a better option.
- SN-38 SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.