Home Biosimilar Antibodies Protein Tyrosine Kinase IGF-1R Robatumumab (Anti-IGF1R / CD221)
For research use only. Not for use in humans.

Robatumumab (Anti-IGF1R / CD221)

Synonyms: Sch 717454

Robatumumab (Anti-IGF1R / CD221) is an antibody targeting human IGF-1R (insulin-like growth factor receptor-1). It shows anti-tumor activity and anti-proliferative activity to cancer cells and can be used in osteosarcoma and Ewing sarcoma research. MW :144.6 KD

Robatumumab (Anti-IGF1R / CD221)

Quality Control

Batch: A304401 Purity: 99% Protein concentration: 12.698mg/ml Endotoxin Level: ＜1EU/mg
99

Specificity

Name Citation IGF-1R Insulin Receptor Others
Linsitinib (OSI-906) 206 IRR
NVP-AEW541 65 FLT3,Tek,FLT1
GSK1904529A 26
NVP-ADW742 24
BMS-536924 26 FAK,MEK,LCK
AG-1024 27
GSK1838705A 18 ALK
BMS-754807 54 TrkB,Met,TrkA
PQ 401 3
Ginsenoside Rg5 0
XL228 0 ABL T315I,LYN,Aurora A
Picropodophyllin (AXL1717) 48
AZD3463 7 ALK
S961 3
Nordihydroguaiaretic acid (NDGA) 1 p300,HER2,lipoxygenase
Expand to Check More
1. "+" indicates inhibitory effect. Increased inhibition is marked by a higher "+" designation. 2. "✔" indicates inhibitory effect, but without specific value.

Mechanism of Action

Description
Robatumumab (Anti-IGF1R / CD221) is an antibody targeting human IGF-1R (insulin-like growth factor receptor-1). It shows anti-tumor activity and anti-proliferative activity to cancer cells and can be used in osteosarcoma and Ewing sarcoma research. MW :144.6 KD
References

Product Details

CAS No. 934235-44-6
Isotype Human IgG1
Source CHO
Formulation 100 mM Pro-Ac, 20mM Arg, pH5.0
Storage
(From the date of receipt)		 Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.

Comparison of Clones for

*Literature analysis of various clone (for this target) products available on the market shows that Selleck's selected clones are more frequently applied. (data until September 2024)

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Handling Instructions

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