Rapamycin (Sirolimus) is a potent, selective mTOR inhibitor. It affects PI3K/AKT/mTOR signaling, inhibiting cell proliferation and tumor growth by binding to FKBP12 to suppress mTORC1 activity and inducing autophagy.
Rapamycin (Sirolimus) IC50 for Cell-based and Cell-free Assays
Comprehensive IC50 Values for Rapamycin (Sirolimus) Across Cell-free Enzyme Inhibitory Profiles and Cell-based Functional Assays.