Osunprotafib (ABBV-CLS-484) is a potent, first-in-class, active-site competitive PTPN2 and PTPN1 inhibitor. It affects JAK-STAT and interferon signaling by preventing the dephosphorylation of key immune proteins, enhancing T cell activation and promoting robust anti-tumor immune responses.
Osunprotafib (ABBV-CLS-484) IC50 for Cell-based and Cell-free Assays
Comprehensive IC50 Values for Osunprotafib (ABBV-CLS-484) Across Cell-free Enzyme Inhibitory Profiles and Cell-based Functional Assays.