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Nedisertib is a potent, selective DNA-PK inhibitor. It affects DNA repair signaling by blocking NHEJ, promoting cell death.
Nedisertib (M3814) Mechanism of Action: DNA-PK Inhibition in Cancer Cell Research
Nedisertib (M3814) MOA：Targeting DNA-PK/NHEJ Pathway for Radiosensitization in Solid Tumors