Nedisertib is a potent, selective DNA-PK inhibitor. It affects DNA repair signaling by blocking NHEJ, promoting cell death.
Nedisertib (M3814) IC50 for Cell-based and Cell-free Assays
Comprehensive IC50 Values for Nedisertib (M3814) Across Cell-free Enzyme Inhibitory Profiles and Cell-based Functional Assays.