🎯 check N-Ethylmaleimide (NEM) product page
N-Ethylmaleimide (NEM) is an irreversible, membrane-permeant cysteine alkylating agent. It affects redox, GABAergic, and autophagic signaling pathways by irreversibly blocking free sulfhydryl groups on cysteine residues, inhibiting cysteine proteases, altering protein functions, and preventing artifactual oxidation.