N-Ethylmaleimide (NEM) is an irreversible, membrane-permeant cysteine alkylating agent. It affects redox, GABAergic, and autophagic signaling pathways by irreversibly blocking free sulfhydryl groups on cysteine residues, inhibiting cysteine proteases, altering protein functions, and preventing artifactual oxidation.
N-Ethylmaleimide (NEM) IC50 for Cell-based and Cell-free Assays
Comprehensive IC50 Values for N-Ethylmaleimide (NEM) Across Cell-free Enzyme Inhibitory Profiles and Cell-based Functional Assays.
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