LB-100 is a selective catalytic PP2A inhibitor. It affects Wnt/β-catenin and mTORC1 signaling pathways, and by inhibiting PP2A enzymatic activity, it inhibits tumor proliferation and EMT, and promotes immune cell activation.
Comprehensive IC50 Values for LB-100 Across Cell-free Enzyme Inhibitory Profiles and Cell-based Functional Assays.
LB-100 is a selective catalytic PP2A inhibitor. It affects Wnt/β-catenin and mTORC1 signaling pathways, and by inhibiting PP2A enzymatic activity, it inhibits tumor proliferation and EMT, and promotes immune cell activation.