ICG-001 is a potent β-catenin/CBP inhibitor. It blocks Wnt/β-catenin signaling by disrupting the protein-protein interaction between β-catenin and CBP, effectively inhibiting cancer cell proliferation, migration, and tissue fibrosis.
Comprehensive IC50 Values for ICG-001 Across Cell-free Enzyme Inhibitory Profiles and Cell-based Functional Assays.
ICG-001 is a potent β-catenin/CBP inhibitor. It blocks Wnt/β-catenin signaling by disrupting the protein-protein interaction between β-catenin and CBP, effectively inhibiting cancer cell proliferation, migration, and tissue fibrosis.