Molecular Weight: 452.55 g/mol
Chemical Structure
Check the
GSK3326595 (Pemrametostat, EPZ015938)
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
91 mg/mL
(201.08 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 32 mg/mL |
| Water | Insoluble |
| DMSO |
90 mg/mL
(198.87 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 90 mg/mL |
| Water | Insoluble |
| DMSO |
91 mg/mL
(201.08 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 91 mg/mL |
| Water | Insoluble |
| DMSO |
91 mg/mL
(201.08 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 20 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Pre-aliquoted for Longevity: Solid-state aliquots offer significantly longer shelf life compared to stock solutions, ensuring maximum stability for every use.
Looking for a specific aliquot size? Reach out to your local sales representative or contact us at orders@selleckchem.com.
| IUPAC Name | 6-[(1-acetylpiperidin-4-yl)amino]-N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]pyrimidine-4-carboxamide | |
|---|---|---|
| CAS Number | 1616392-22-3 | |
| Molecular Formula |
C24H32N6O3 |
|
| Molecular Weight (MW) | 452.55 | |
| SMILES | CC(=O)N1CCC(CC1)NC2=NC=NC(=C2)C(=O)NCC(CN3CCC4=CC=CC=C4C3)O | |
| InChIKey | JLCCNYVTIWRPIZ-NRFANRHFSA-N |
- GSK3326595 (Pemrametostat, EPZ015938) Mechanism of Action: PRMT5 Inhibition in Cancer Cell Research
- GSK3326595 (Pemrametostat, EPZ015938) Clinical Trials
- GSK3326595 (Pemrametostat, EPZ015938) Working Concentration | Cell Culture | Treatment
- GSK3326595 (Pemrametostat, EPZ015938) Solubility in DMSO
- GSK3326595 (Pemrametostat, EPZ015938) Stock Solution
- GSK3326595 (Pemrametostat, EPZ015938) Storage
- GSK3326595 (Pemrametostat, EPZ015938) Stability
- GSK3326595 (Pemrametostat, EPZ015938) Combination Database
- GSK3326595 (Pemrametostat, EPZ015938) SMILES
- GSK3326595 (Pemrametostat, EPZ015938) CAS Number
- GSK3326595 (Pemrametostat, EPZ015938) Chemical Structure (2D and 3D)
- GSK3326595 (Pemrametostat, EPZ015938) IC50 for Cell-based and Cell-free Assays
- GSK3326595 (Pemrametostat, EPZ015938) Cayman (27305)? Try a better option.
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- GSK3326595 (Pemrametostat, EPZ015938) SDS|MSDS
Note: Technical data last updated: Sep 1, 2026.