Setanaxib (GKT137831) IC50 for Cell-based and Cell-free Assays

Setanaxib (GKT137831) is a potent, selective NOX1/4 inhibitor. It affects MAPK, NF-κB, and TGF-β signaling by reducing ROS production and alleviating mitochondrial dysfunction, effectively inhibiting apoptosis, inflammation, fibrosis, and tumor progression.

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