2D Structure
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2D chemical structural formula diagram.
3D Structure
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This 3D model represents a theoretically simulated conformation and is for reference only.
Check the
Setanaxib (GKT137831)
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | 2-(2-chlorophenyl)-4-[3-(dimethylamino)phenyl]-5-methyl-1H-pyrazolo[4,3-c]pyridine-3,6-dione | |
|---|---|---|
| CAS Number | 1218942-37-0 | |
| Molecular Formula |
C21H19ClN4O2 |
|
| Molecular Weight (MW) | 394.85 | |
| SMILES | CN1C(=O)C=C2C(=C1C3=CC(=CC=C3)N(C)C)C(=O)N(N2)C4=CC=CC=C4Cl | |
| InChIKey | RGYQPQARIQKJKH-UHFFFAOYSA-N |
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
78 mg/mL
(197.54 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
| DMSO |
78 mg/mL
(197.54 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
| DMSO |
78 mg/mL
(197.54 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
| DMSO |
78 mg/mL
(197.54 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
| DMSO |
78 mg/mL
(197.54 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Pre-aliquoted for Longevity: Solid-state aliquots offer significantly longer shelf life compared to stock solutions, ensuring maximum stability for every use.
Looking for a specific aliquot size? Reach out to your local sales representative or contact us at orders@selleckchem.com.
- Setanaxib (GKT137831) Mechanism of Action: NOX1/4 Inhibition in Hepatic Stellate Cells Research
- Setanaxib (GKT137831) Clinical Trials
- Setanaxib (GKT137831): Selectivity & Specificity
- Setanaxib (GKT137831) Working Concentration | Cell Culture | Treatment
- Setanaxib (GKT137831) Solubility in DMSO
- Setanaxib (GKT137831) Stock Solution
- Setanaxib (GKT137831) Storage
- Setanaxib (GKT137831) Stability
- Setanaxib (GKT137831) Combination Database
- Setanaxib (GKT137831) Molecular Weight
- Setanaxib (GKT137831) SMILES
- Setanaxib (GKT137831) CAS Number
- Setanaxib (GKT137831) IC50 for Cell-based and Cell-free Assays
- Setanaxib (GKT137831) Cayman (17764)? Try a better option.
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- Setanaxib (GKT137831) MedChemExpress (HY-12298)? Try a better option.
- Setanaxib (GKT137831) Sigma (BL3H1F1C8486)? Try a better option.
- Setanaxib (GKT137831) SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.