Entinostat (MS-275) is a potent, selective class I HDAC inhibitor. It affects Wnt, Hippo, and STAT signaling by inducing histone hyperacetylation and altering gene transcription, effectively inhibiting tumor proliferation and promoting apoptosis and anti-tumor immunity.
Entinostat (MS-275) IC50 for Cell-based and Cell-free Assays
Comprehensive IC50 Values for Entinostat (MS-275) Across Cell-free Enzyme Inhibitory Profiles and Cell-based Functional Assays.