SMILES:
C1=CC=C(C(=C1)N)NC(=O)C2=CC=C(C=C2)CNC(=O)OCC3=CN=CC=C3
Chemical Structure
Check the
Entinostat (MS-275)
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | pyridin-3-ylmethyl N-[[4-[(2-aminophenyl)carbamoyl]phenyl]methyl]carbamate | |
|---|---|---|
| CAS Number | 209783-80-2 | |
| Molecular Formula |
C21H20N4O3 |
|
| Molecular Weight (MW) | 376.41 | |
| SMILES | C1=CC=C(C(=C1)N)NC(=O)C2=CC=C(C=C2)CNC(=O)OCC3=CN=CC=C3 | |
| InChIKey | INVTYAOGFAGBOE-UHFFFAOYSA-N |
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
75 mg/mL
(199.25 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
| DMSO |
75 mg/mL
(199.25 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
| DMSO |
75 mg/mL
(199.25 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
| DMSO |
75 mg/mL
(199.25 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
| DMSO |
75 mg/mL
(199.25 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Pre-aliquoted for Longevity: Solid-state aliquots offer significantly longer shelf life compared to stock solutions, ensuring maximum stability for every use.
Looking for a specific aliquot size? Reach out to your local sales representative or contact us at orders@selleckchem.com.
- Entinostat (MS-275) Mechanism of Action: HDAC1 Inhibition in Breast Cancer Cell Research
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- Entinostat (MS-275): Selectivity & Specificity
- Entinostat (MS-275) Working Concentration | Cell Culture | Treatment
- Entinostat (MS-275) Solubility in DMSO
- Entinostat (MS-275) Stock Solution
- Entinostat (MS-275) Storage
- Entinostat (MS-275) Stability
- Entinostat (MS-275) Combination Database
- Entinostat (MS-275) Molecular Weight
- Entinostat (MS-275) CAS Number
- Entinostat (MS-275) Chemical Structure (2D and 3D)
- Entinostat (MS-275) IC50 for Cell-based and Cell-free Assays
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- Entinostat (MS-275) SDS|MSDS
Note: Technical data last updated: Sep 1, 2026.