Cilengitide (EMD 121974): Selectivity & Specificity

Cilengitide (EMD 121974) is a potent inhibitor of αvβ3 (5400 ± 814 nM) and αvβ5. Cilengitide (EMD 121974) exhibits the greatest inhibitory potency toward αvβ3 (IC50 = 5400 ± 814 nM).