2D Structure
loading...
2D chemical structural formula diagram.
3D Structure
loading...
This 3D model represents a theoretically simulated conformation and is for reference only.
Check the
Cilengitide (EMD 121974)
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | 2-[(2S,5R,8S,11S)-5-benzyl-11-[3-(diaminomethylideneamino)propyl]-7-methyl-3,6,9,12,15-pentaoxo-8-propan-2-yl-1,4,7,10,13-pentazacyclopentadec-2-yl]acetic acid | |
|---|---|---|
| CAS Number | 188968-51-6 | |
| Molecular Formula |
C27H40N8O7 |
|
| Molecular Weight (MW) | 588.66 | |
| SMILES | CC(C)C1N(C)C(=O)C(CC2=CC=CC=C2)NC(=O)C(CC(O)=O)NC(=O)CNC(=O)C(CCCNC(N)=N)NC1=O | |
| InChIKey | AMLYAMJWYAIXIA-VWNVYAMZSA-N |
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
100 mg/mL
(169.87 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 5 mg/mL (超声加热十分钟，60℃) |
| Ethanol | Insoluble |
| DMSO |
100 mg/mL
(169.87 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 20 mg/mL |
| Ethanol | Insoluble |
| DMSO |
100 mg/mL
(169.87 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
- Cilengitide (EMD 121974) Mechanism of Action: αvβ3 Integrin Inhibition in Tumor Cells Research
- Cilengitide (EMD 121974) Clinical Trials
- Cilengitide (EMD 121974): Selectivity & Specificity
- Cilengitide (EMD 121974) Working Concentration | Cell Culture | Treatment
- Cilengitide (EMD 121974) Solubility in DMSO
- Cilengitide (EMD 121974) Stock Solution
- Cilengitide (EMD 121974) Storage
- Cilengitide (EMD 121974) Stability
- Cilengitide (EMD 121974) Combination Database
- Cilengitide (EMD 121974) Molecular Weight
- Cilengitide (EMD 121974) SMILES
- Cilengitide (EMD 121974) CAS Number
- Cilengitide (EMD 121974) IC50 for Cell-based and Cell-free Assays
- Cilengitide (EMD 121974) Sigma (SML1594)? Try a better option.
- Cilengitide (EMD 121974) Tocris (5870)? Try a better option.
- Cilengitide (EMD 121974) APExBIO (A8660)? Try a better option.
- Cilengitide (EMD 121974) MedChemExpress (HY-16141)? Try a better option.
- Cilengitide (EMD 121974) SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.