Bardoxolone Methyl (RTA 402) IC50 for Cell-based and Cell-free Assays

Comprehensive IC50 Values for Bardoxolone Methyl (RTA 402) Across Cell-free Enzyme Inhibitory Profiles and Cell-based Functional Assays.

Bardoxolone Methyl (RTA 402) is a potent, covalent KEAP1 inhibitor and NRF2 activator. It affects NRF2 and NF-κB signaling pathways by forming an adduct with KEAP1 and blocking IκB kinase, inhibiting inflammation, oxidative stress, and apoptosis while promoting cytoprotection.

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