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Avapritinib is a potent KIT/PDGFRA inhibitor. It affects Akt/Erk signaling by binding kinase domains to inhibit tumor growth.
Avapritinib (BLU-285): Mechanism of Action
Avapritinib (BLU-285) MOA：Targeting KIT/KIT Signaling Pathway for Systemic Mastocytosis
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