Anti-mouse TNFα-InVivo [XT3.11]

Catalog No.A2124        Batch: A212403

       Clone No.XT3.11

Print

Anti-mouse TNFα-InVivo reacts with mouse TNFα (tumor necrosis factor-alpha), a multifunctional proinflammatory cytokine. TNFα dysregulation is been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. TNFα knockout animals display defects in response to bacterial infection, characterized by defects in forming organized follicular dendritic cell networks and germinal centers with a lack of primary B cell follicles.

Technical Data

Formulation PBS, pH 8.0 Contains no stabilizers or preservatives
Clone XT3.11
Isotype Rat IgG1
Application in vitro &in vivo TNFα neutralization, Western blot
Source CHO
Murine Pathogen Screening Panel all targets tested yielded Negative Results: Theiler’s Murine Encephalomyelitis Virus, Ectromelia (Mousepox) Virus, Hantavirus, Polyomavirus, Sendai Virus, Mycoplasma pulmonis, Pneumonia Virus of Mice, K Virus, Mouse Parvovirus, Mouse Hepatitis Virus, Mouse Norovirus, Mouse Minute Virus, Mouse Cytomegalovirus, Mouse Adenovirus, Lactate Dehydrogenase-Elevating Virus, Reovirus Panel, Lymphocytic Choriomeningitis Virus, Mouse Rotavirus.
Storage
(From the date of receipt)		 Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles
Sterility 6.15 mg/mL
Purity 99%
Protein concentration 6.15 mg/mL
Endotoxin Level ＜1 EU/mg

Selleck's Anti-mouse TNFα-InVivo [XT3.11] Has Been Cited by 3 publications

Spatial and temporal single cell multi-omics in mice reveals macrophage-SFRP4+ stroma interactions promoting endometrial regeneration via TNF-α [ Cell Reports, June 1, 2026, 45(6):117434]

https://www.ncbi.nlm.nih.gov/pubmed/?term=42234562
Neutralizing LFA-1 alleviates acute lung injury by diminishing pulmonary retention of CAR-T cells [ Pharmacological Research, August 1, 2026, 230:108292]

https://www.ncbi.nlm.nih.gov/pubmed/?term=42285385
DNAM-1 immunoreceptor integrates innate and adaptive immune programs to drive intestinal inflammation [ bioRxiv, April 1, 2026, 2026.03.30.715436]

FOR RESEARCH USE ONLY. NOT FOR USE IN HUMANS.

Specific storage and handling information for each product is indicated on the product datasheet. Most Selleck products are stable under the recommended conditions. Products are sometimes shipped at a temperature that differs from the recommended storage temperature. Short-term storage of many products are stable in the short-term at temperatures that differ from that required for long-term storage.
We ensure that the product is shipped under conditions that will maintain the quality of the reagents. Upon receipt of the product, follow the storage recommendations on the product data sheet.