Anti-mouse CTLA-4 (CD152)-InVivo [9H10]

Catalog No.A2103        Batch: A210312

       Clone No.9H10

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Anti-mouse CTLA-4 (CD152) antibody (Clone:9H10) reacts with mouse CTLA-4 (cytotoxic T lymphocyte antigen-4) also known as CD152. Anti-mouse CTLA-4 (CD152) antibody has been shown to promote T cell co-stimulation by blocking CTLA-4 binding to the B7 co-receptors, allowing for CD28 binding.

Technical Data

Formulation PBS buffer, pH 7.0
Clone 9H10
Immunogen Mouse CTLA-4-human IgG1 fusion protein
Isotype Syrian hamster IgG
Application in vivo/vitro CTLA-4 neutralization, FCM,WB
Source CHO
Murine Pathogen Screening Panel all targets tested yielded Negative Results: Theiler’s Murine Encephalomyelitis Virus, Ectromelia (Mousepox) Virus, Hantavirus, Polyomavirus, Sendai Virus, Mycoplasma pulmonis, Pneumonia Virus of Mice, K Virus, Mouse Parvovirus, Mouse Hepatitis Virus, Mouse Norovirus, Mouse Minute Virus, Mouse Cytomegalovirus, Mouse Adenovirus, Lactate Dehydrogenase-Elevating Virus, Reovirus Panel, Lymphocytic Choriomeningitis Virus, Mouse Rotavirus.
Storage
(From the date of receipt)		 Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles
Sterility 12.55 mg/mL
Purity 99%
Protein concentration 12.55 mg/mL
Endotoxin Level ＜1EU/mg

Selleck's Anti-mouse CTLA-4 (CD152)-InVivo [9H10] Has Been Cited by 5 publications

N-terminal acetylation of transcription factor LIP induces immune therapy resistance via suppression of PD-L1 expression in non-small cell lung cancer [ Journal for Immunotherapy of Cancer, November 1, 2024, 12(11):e009905]

https://www.ncbi.nlm.nih.gov/pubmed/?term=39615895
HBx hijacks the miR‐19a‐3p/BAMBI/TGF‐β1 axis to impair the anti‐tumour activity of CD4+ T cells in diffuse large B‐cell lymphoma [ Clinical and Translational Medicine, January 2026, e70578]

https://www.ncbi.nlm.nih.gov/pubmed/?term=41492119
HBx hijacks the miR‐19a‐3p/BAMBI/TGF‐β1 axis to impair the anti‐tumour activity of CD4 + T cells in diffuse large B‐cell lymphoma [ Clinical and Translational Medicine, January 1, 2026, 16(1):e70578]

https://www.ncbi.nlm.nih.gov/pubmed/?term=41492119
HE4 drives PD-L1 expression in myeloid cells via IFN-γR-JAK-STAT3 signaling to promote tumor immune evasion [ Cell Reports Medicine, April 1, 2026, 7(4):102691]

https://www.ncbi.nlm.nih.gov/pubmed/?term=41861828
N-terminal acetylation of transcription factor LIP induces immune therapy resistance via suppression of PD-L1 expression in non-small cell lung cancer [ J Immunother Cancer, 2024, 12(11)e009905]

https://www.ncbi.nlm.nih.gov/pubmed/?term=39615895

FOR RESEARCH USE ONLY. NOT FOR USE IN HUMANS.

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