Abemaciclib (LY2835219) is stable under recommended storage conditions.
Recommended storage conditions are listed in the table below.
| Form | Storage Temp | Shelf Life |
|---|---|---|
| 3 years -20°C powder | ||
| In Solvent | -80°C | 1 year |
| In Solvent | -20°C | 1 month |
Check the
Abemaciclib (LY2835219)
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| Ethanol | 8 mg/mL |
| DMSO |
6 mg/mL
(11.84 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| DMSO |
10 mg/mL
(19.73 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 6 mg/mL |
| Water | Insoluble |
| Ethanol | 11 mg/mL |
| DMSO |
4 mg/mL
(7.89 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.) |
| Water | Insoluble |
| Ethanol | 10 mg/mL |
| DMSO |
3 mg/mL
(5.92 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.) |
| Water | Insoluble |
| Ethanol | 13 mg/mL |
| DMSO |
2 mg/mL
(3.94 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.) |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Pre-aliquoted for Longevity: Solid-state aliquots offer significantly longer shelf life compared to stock solutions, ensuring maximum stability for every use.
Looking for a specific aliquot size? Reach out to your local sales representative or contact us at orders@selleckchem.com.
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- Abemaciclib (LY2835219): Selectivity & Specificity
- Abemaciclib (LY2835219) Working Concentration | Cell Culture | Treatment
- Abemaciclib (LY2835219) Solubility in DMSO
- Abemaciclib (LY2835219) Stock Solution
- Abemaciclib (LY2835219) Storage
- Abemaciclib (LY2835219) Combination Database
- Abemaciclib (LY2835219) Molecular Weight
- Abemaciclib (LY2835219) SMILES
- Abemaciclib (LY2835219) CAS Number
- Abemaciclib (LY2835219) Chemical Structure (2D and 3D)
- Abemaciclib (LY2835219) IC50 for Cell-based and Cell-free Assays
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Note: Technical data last updated: Sep 1, 2026.