CAS No. 57-83-0
| IUPAC Name | (8S,9S,10R,13S,14S,17S)-17-acetyl-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one | |
|---|---|---|
| CAS Number | 57-83-0 | |
| Molecular Formula |
C21H30O2 |
|
| Molecular Weight (MW) | 314.46 | |
| SMILES | CC(=O)C1CCC2C1(CCC3C2CCC4=CC(=O)CCC34C)C | |
| InChIKey | RJKFOVLPORLFTN-LEKSSAKUSA-N |
Progesterone is an endogenous steroid hormone that acts as a potent agonist of the nuclear progesterone receptor (nPR, Kd 1 nM), an agonist of membrane progesterone receptors (mPRs), and an antagonist of the sigma-1 receptor. Ligand binding modulates downstream gene transcription and rapid non-genomic signaling pathways, promoting cellular differentiation and supporting key reproductive processes including menstrual cycle regulation, embryogenesis, and pregnancy maintenance. [1]
|
Concentration
Volume
Mass
|
|---|
| Solvent | Solubility & Note |
|---|---|
| DMSO |
40 mg/mL
(127.2 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 20 mg/mL |
| Water | Insoluble |
| DMSO |
63 mg/mL
(200.34 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 63 mg/mL |
| Water | Insoluble |
| Ethanol | 31.5 mg/mL |
| DMSO |
22 mg/mL
(69.96 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Pre-aliquoted for Longevity: Solid-state aliquots offer significantly longer shelf life compared to stock solutions, ensuring maximum stability for every use.
Looking for a specific aliquot size? Reach out to your local sales representative or contact us at orders@selleckchem.com.