Cell-free Assays (IC50/Ki) for Celecoxib (SC-58635)

Key TargetIC50 (Cell-free)DescriptionReference
Human Carbonic Anhydrase II, Human Carbonic Anhydrase IX, Human Carbonic Anhydrase XII CA-II: 21 nM, CA-IX: 16 nM, CA-XII: 18 nM Enzyme inhibition assay Download PDF
LOX enzyme 11.6 μg/ml Enzymatic assay (colorimetric) Download PDF
COX-1 8.73 µM whole blood assay Download PDF
Recombinant human CYP2C9 20.10 µM Metabolism rate of agomelatine, quantified using UPLC-MS/MS. PMC5849912
COX-2 40 nM in vitro inhibition assay Download PDF

Cell-based Assay (IC50) for Celecoxib (SC-58635)

Cell TypeIC50 (Cell-based)DescriptionReference
KYSE150 cells 87.79 μM CCK-8 assay PMC12628407
U-138 MG 8.6 ±0.6 µM MTT assay Download PDF
T98G 8.0 ±0.4 µM MTT assay Download PDF
HA 10.4 ±1.0 µM MTT assay Download PDF
BJ 77.61 µM Neutral Red (NR) assay Download PDF
Check the Celecoxib (SC-58635) product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

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