Clinical Trials

Celecoxib has been evaluated in numerous clinical trials ranging from Phase 1 through Phase 4, with recruitment statuses encompassing completed, active, and recruiting studies. These investigations assess the agent across diverse indications, including knee osteoarthritis, postoperative pain, pediatric pharmacokinetics, major depressive disorder, and metastatic prostate cancer. Broadly sponsored by academic medical centers, hospital health systems, government agencies, and pharmaceutical companies, completed trials have evaluated outcomes such as the compound's effect on neuroinflammation in depression.

NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT03026140 RECRUITING
Colon Carcinoma
The Netherlands Cancer Institute
2017-03-29 PHASE2
NCT06699966 NOT_YET_RECRUITING
Major Depressive Disorder
Stony Brook University
2027-06 PHASE4
NCT06942039 RECRUITING
CNS Embryonal Tumor; CNS, Medulloblastoma; Atypical Teratoid Rhabdoid Tumor; Medulloblastoma, Childhood; Medulloblastoma, Group 3; Medulloblastoma, Group 4; Pineoblastoma; Neuroblastoma; Embryonal Tumor With Multilayered Rosettes; Embryonal Tumor With Abundant Neuropil and True Rosettes; Ependymoblastoma; Medulloepithelioma; CNS Embryonal Tumor With Rhabdoid Features; CNS Embryonal Tumor, Nos
C17 Council
2025-09-23 EARLY_PHASE1
NCT03686657 WITHDRAWN
Type 2 Diabetes; High Blood Pressure; Arthritis; Obesity
ARKAY Therapeutics
2026-12-10 PHASE1; PHASE2
NCT01356290 RECRUITING
Medulloblastoma Recurrent; Ependymoma Recurrent; ATRT Recurrent; Rare CNS Tumor Recurrent
Medical University of Vienna
2014-04 PHASE2
NCT07632235 NOT_YET_RECRUITING
Intrahepatic Cholangiocarcinoma (Icc)
Shanghai 6th People's Hospital
2026-09-15 PHASE1; PHASE2
NCT04469530 RECRUITING
Solid Tumor
Emory University
2020-09-16 PHASE2
NCT06722534 RECRUITING
Peutz-Jeghers Syndrome; Celecoxib; Small Bowel Polyp
Air Force Military Medical University, China
2025-02-01
NCT07104266 RECRUITING
Triple-Negative Breast Cancer
Université de Sherbrooke
2025-08-04 PHASE2
NCT07154316 RECRUITING
Colorectal Cancer
Fudan University
2025-08-01 PHASE2
NCT07634094 NOT_YET_RECRUITING
Ovarian Cancer
Kalinski, Pawel, MD, PhD
2026-08 PHASE2
NCT04488081 ACTIVE_NOT_RECRUITING
COVID-19
QuantumLeap Healthcare Collaborative
2020-07-31 PHASE2
NCT04860635 SUSPENDED
Analgesia
Arthritis Innovation Corporation
2027-01 PHASE2; PHASE3
NCT06997068 RECRUITING
Metastatic Oral Cavity Carcinoma; Recurrent Oral Cavity Carcinoma; Stage IVC Lip and Oral Cavity Cancer AJCC v8; Head and Neck Cancer; Hypopharynx Cancer; Oropharynx Cancer; Clinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8; Metastatic Hypopharyngeal Carcinoma; Metastatic Laryngeal Carcinoma; Metastatic Malignant Head and Neck Neoplasm; Metastatic Oropharyngeal Carcinoma; Recurrent Hypopharyngeal Carcinoma; Recurrent Laryngeal Carcinoma; Recurrent Malignant Head and Neck Neoplasm; Recurrent Oropharyngeal Carcinoma; Stage IVC Hypopharyngeal Carcinoma AJCC v8; Stage IVC Laryngeal Cancer AJCC v8; Stage IVC Oropharyngeal (p16-Negative) Carcinoma AJCC v8
Mayo Clinic
2025-07-09 PHASE2
NCT06903858 RECRUITING
Colorectal Cancer; Microsatellite Instability High; Mismatch Repair Deficiency
Sun Yat-sen University
2025-06-01 PHASE2
NCT07494565 RECRUITING
Diffuse Large B-Cell Lymphoma (DLBCL); CD5 Positive
Sun Yat-sen University
2026-03-06 PHASE2
NCT03590821 NOT_YET_RECRUITING
Healthy
University of Pennsylvania
2027-12 EARLY_PHASE1
NCT07673549 NOT_YET_RECRUITING
Idiopathic Trigeminal Neuralgia
Beijing Tiantan Hospital
2026-08-31
NCT02993029 RECRUITING
Treatment Outcome
Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
2017-09-01
NCT07139405 NOT_YET_RECRUITING
Type 2 Diabetes (T2DM)
Myopharm Limited
2026-09-01 PHASE2
NCT06505187 RECRUITING
Parotidectomy
University of Wisconsin, Madison
2025-02-28 PHASE2
NCT07150949 RECRUITING
Locally Advanced Rectal Cancer; Neoadjuvant Therapy
Fudan University
2025-08-28 PHASE2
NCT05434065 RECRUITING
Intracerebral Hemorrhage
National Taiwan University Hospital
2023-01-01 PHASE2
NCT05343013 RECRUITING
Colorectal Cancer
M.D. Anderson Cancer Center
2022-06-06 PHASE2
NCT03926338 RECRUITING
Colorectal Cancer; Mismatch Repair-deficient (dMMR); Microsatellite Instability-high (MSI-H); Neoadjuvant Therapy
Sun Yat-sen University
2019-05-10 PHASE2
NCT04041050 ACTIVE_NOT_RECRUITING
Myeloproliferative Neoplasm
AbbVie
2019-11-08 PHASE1
NCT05731726 RECRUITING
pMMR; MSS; MSI-L; Locally Advanced Rectal Carcinoma
Zhejiang University
2023-02-22 PHASE2
NCT05637086 RECRUITING
Epilepsy
Mostafa Bahaa
2022-12-20 PHASE2
NCT07246278 RECRUITING
Parkinson Disease
Tanta University
2025-11-20 PHASE1; PHASE2
NCT06231758 RECRUITING
Osteo Arthritis Knee
Mostafa Bahaa
2024-01-30 PHASE3
NCT07174570 RECRUITING
Advanced Hepatocellular Carcinoma; Metastatic Hepatocellular Carcinoma; Stage III Hepatocellular Carcinoma AJCC v8; Stage IV Hepatocellular Carcinoma AJCC v8
Emory University
2026-01-02 PHASE2
NCT05644301 RECRUITING
Major Depressive Disorder; Inflammation
Universiteit Antwerpen
2023-09-21 PHASE3
NCT04786548 SUSPENDED
Obsessive-Compulsive Disorder
New York State Psychiatric Institute
2021-04-01 PHASE2
NCT07351968 RECRUITING
Moderate Pain in Knee Osteoarthritis; Severe Pain in Knee Osteoarthritis
Shandong Suncadia Medicine Co., Ltd.
2026-03-10 PHASE1
NCT05415397 ACTIVE_NOT_RECRUITING
Depressive Disorder, Major; Inflammation
Amsterdam UMC, location VUmc
2022-09-28 PHASE3
NCT07543796 RECRUITING
Postoperative Analgesia After Unilateral Hip Arthroplasty
Beijing Tide Pharmaceutical Co., Ltd
2026-03-18 PHASE2
NCT06545526 UNKNOWN
Familial Adenomatous Polyposis
Yonsei University
2024-08-13 PHASE3
NCT05852093 NOT_YET_RECRUITING
Rotator Cuff Tears
Second Affiliated Hospital, Zhejiang University, School of Medicine
2023-06-01 EARLY_PHASE1
NCT02574728 ACTIVE_NOT_RECRUITING
Cancer
Emory University
2015-06 PHASE2
NCT06379425 RECRUITING
Pain, Postoperative; Postoperative Pain, Acute
Northwell Health
2024-03-01 PHASE4
NCT00268476 ACTIVE_NOT_RECRUITING
Prostate Cancer
Medical Research Council
2005-07-08 PHASE2; PHASE3
NCT04147013 ACTIVE_NOT_RECRUITING
Chronic Rhinosinusitis with Nasal Polyps; Aspirin-exacerbated Respiratory Disease
London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
2020-02-18 PHASE4
NCT01344200 RECRUITING
Pharmacokinetics of Celecoxib in Children
Children's Hospital of Eastern Ontario
2024-01-29 PHASE2
NCT06076837 TERMINATED
Pancreatic Cancer Metastatic; Pancreatic Adenocarcinoma Metastatic
HonorHealth Research Institute
2025-01-09 PHASE1
NCT05077332 COMPLETED
2019 Novel Coronavirus Disease; 2019 Novel Coronavirus Infection; 2019-nCoV Disease; 2019-nCoV Infection; COVID-19 Pandemic; COVID-19 Virus Disease; COVID-19 Virus Infection; Covid19; Coronavirus Disease 2019; SARS-CoV-2 Infection; SARS-CoV-2 Acute Respiratory Disease; COVID-19
Leidos Life Sciences
2021-12-29 PHASE2
NCT06863636 RECRUITING
Joint Pain; Knee Osteoarthritis; Hip Osteoarthritis
Laboratorios Silanes S.A. de C.V.
2024-09-09 PHASE3
NCT05933980 UNKNOWN
Colorectal Cancer; Liver Metastases; MSS
Sun Yat-sen University
2023-12-19 PHASE2
NCT07559682 ACTIVE_NOT_RECRUITING
Orthodontic Pain (D013850)
Sharif Medical Research Center
2025-05-08 PHASE1
NCT04814355 COMPLETED
Major Depressive Disorder; Neuroinflammation
Stony Brook University
2018-08-01 PHASE4
NCT03645187 UNKNOWN
Colon Cancer Stage
Sherief Abd-Elsalam
2018-08-01 PHASE4
NCT02432378 WITHDRAWN
Cancer of Ovary; Cancer of the Ovary; Neoplasms, Ovarian; Ovarian Cancer; Ovary Cancer; Ovary Neoplasms
Roswell Park Cancer Institute
2015-09-04 PHASE1; PHASE2
NCT06451783 UNKNOWN
Osteoarthritis of the Knee
Xuhui Central Hospital, Shanghai
2024-05-01 EARLY_PHASE1
NCT05756166 TERMINATED
Anatomic Stage IV Breast Cancer AJCC v8; Metastatic Triple-Negative Breast Carcinoma; Unresectable Triple-Negative Breast Carcinoma
Roswell Park Cancer Institute
2024-02-16 PHASE1; PHASE2
NCT04093323 TERMINATED
HLA-A2 Positive Cells Present; Refractory Melanoma
Roswell Park Cancer Institute
2024-11-13 PHASE2
NCT06285617 UNKNOWN
Subacute Thyroiditis
Xinqiao Hospital of Chongqing
2024-04-01 PHASE3
NCT06159114 COMPLETED
Chronic Prostatitis
Xintian Pharmaceutical
2023-12-19 PHASE4
NCT06516094 COMPLETED
Chronic Low-back Pain
Laboratorios Silanes S.A. de C.V.
2024-04-11 PHASE3
NCT05578287 UNKNOWN
Colorectal Cancer
Sun Yat-sen University
2023-07-18 PHASE2
NCT05488847 ACTIVE_NOT_RECRUITING
Shoulder Arthropathy; Shoulder Pain
Henry Ford Health System
2022-06-25 PHASE4
NCT06316843 COMPLETED
Long COVID; PASC Post Acute Sequelae of COVID 19
Bateman Horne Center
2023-10-15 PHASE2
NCT06337422 UNKNOWN
Healthy Volunteer
International Bio service
2024-09-23 PHASE1
NCT05962957 COMPLETED
Parkinson Disease
Mostafa Bahaa
2023-08-07 PHASE2
NCT04120636 UNKNOWN
Macula Edema; Radiation Retinopathy; Branch Retinal Vein Occlusion; Epiretinal Membrane; Central Serous Retinopathy With Pit of Optic Disc; Commotio Retinae; Vitritis
Targeted Therapy Technologies, LLC
2021-03-05 PHASE1
NCT03912428 TERMINATED
Myositis; Inflammatory; Rheumatoid Arthritis; Healthy Volunteers
National Institute of Mental Health (NIMH)
2019-06-14 PHASE1
NCT05327751 UNKNOWN
Hand and Foot Syndrome; Erythrodysesthesia Syndrome; HFS; Colorectal Cancer
Tanta University
2022-04-01 PHASE3
NCT03710876 COMPLETED
Malignant Pleural Mesothelioma
Ferring Ventures Limited
2019-01-21 PHASE3
NCT05281276 TERMINATED
Metastatic Colorectal Cancer
Taipei Medical University Shuang Ho Hospital
2022-09-20 PHASE1
NCT02885974 COMPLETED
Bladder Cancer
Baylor College of Medicine
2016-12 PHASE1
NCT01344200 Recruiting
Pharmacokinetics of Celecoxib in Children
Children''s Hospital of Eastern Ontario
2024-01-29 Phase 2
NCT02030964 COMPLETED
Neuroblastoma
New Approaches to Neuroblastoma Therapy Consortium
2014-01-16 PHASE1
NCT05288374 COMPLETED
Pain, Postoperative
Charles University, Czech Republic
2022-02-10 PHASE4
NCT03728179 COMPLETED
Solid Tumor, Adult
Centre Hospitalier Universitaire Vaudois
2019-01-16 PHASE1
NCT05911126 UNKNOWN
Pain
Cairo University
2023-06-13
NCT05062083 TERMINATED
Multiple Sclerosis
National Institute of Mental Health (NIMH)
2022-06-07 PHASE2
NCT06009900 UNKNOWN
Pain, Chronic
Tongji Hospital
2023-09-01
NCT04115098 TERMINATED
Axial Spondyloarthritis
The University of Texas Health Science Center, Houston
2020-06-25 PHASE2
NCT05555823 COMPLETED
Healthy
Atriva Therapeutics GmbH
2022-06-23 PHASE1
NCT07804979 COMPLETED
Major Depressive Disorder (MDD); Treatment-resistant Depression (TRD)
Lahore General Hospital
2022-05-12
NCT06336993 COMPLETED
Low Back Pain
Zhejiang Provincial Tongde Hospital
2022-01-01 PHASE4
NCT05476679 COMPLETED
Submental Fat
Raziel Therapeutics Ltd.
2022-09-25 PHASE1; PHASE2
NCT04673578 UNKNOWN
Obsessive-Compulsive Disorder; Pediatric Psychiatric Disorder
University of British Columbia
2021-06-01 PHASE2
NCT05509946 UNKNOWN
Arthroplasty Complications; Analgetic; Celecoxib; Pregabalin
Indonesia University
2022-10-01 PHASE2; PHASE3
NCT05512013 COMPLETED
Bone Resorption; Stress Fracture; Bone Injury
United States Army Research Institute of Environmental Medicine
2022-02-15 PHASE1
NCT03643744 TERMINATED
Actinic Keratosis; Photodynamic Therapy
Wright State University
2019-04-01 PHASE1
NCT04790812 COMPLETED
Pain, Postoperative
The University of Texas Health Science Center, Houston
2021-04-22 PHASE4
NCT04162873 TERMINATED
Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8; Clinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8; Nasal Cavity and Paranasal Sinus Carcinoma; Oral Cavity Carcinoma; Pathologic Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8; Pathologic Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8; Recurrent Hypopharyngeal Carcinoma; Recurrent Laryngeal Carcinoma; Recurrent Nasal Cavity and Paranasal Sinus Carcinoma; Recurrent Oral Cavity Carcinoma; Recurrent Oropharyngeal Carcinoma; Stage III Hypopharyngeal Carcinoma AJCC v8; Stage III Laryngeal Cancer AJCC v8; Stage III Oropharyngeal (p16-Negative) Carcinoma AJCC v8; Stage IV Hypopharyngeal Carcinoma AJCC v8; Stage IV Laryngeal Cancer AJCC v8; Stage IV Oropharyngeal (p16-Negative) Carcinoma AJCC v8; Stage IVA Hypopharyngeal Carcinoma AJCC v8; Stage IVA Laryngeal Cancer AJCC v8; Stage IVA Oropharyngeal (p16-Negative) Carcinoma AJCC v8; Stage IVB Hypopharyngeal Carcinoma AJCC v8; Stage IVB Laryngeal Cancer AJCC v8; Stage IVB Oropharyngeal (p16-Negative) Carcinoma AJCC v8; Stage IVC Hypopharyngeal Carcinoma AJCC v8; Stage IVC Laryngeal Cancer AJCC v8; Stage IVC Oropharyngeal (p16-Negative) Carcinoma AJCC v8
University of Utah
2019-11-27 PHASE2
NCT05085574 WITHDRAWN
2019 Novel Coronavirus Disease; 2019 Novel Coronavirus Infection; 2019-nCoV Disease; 2019-nCoV Infection; COVID-19 Pandemic; COVID-19 Virus Disease; COVID-19 Virus Infection; Covid19; Coronavirus Disease 2019; SARS-CoV-2 Infection; SARS-CoV-2 Acute Respiratory Disease; COVID-19
Leidos Life Sciences
2023-02-07 PHASE2
NCT05324163 COMPLETED
KNEE OSTEOARTHRITIS
Jiangsu XinChen-Techfields Pharma Co., LTD.
2021-09-29 PHASE3
NCT05362851 UNKNOWN
Osteoarthritis, Knee
Yooyoung Pharmaceutical Co., Ltd.
2021-11-11 PHASE3
NCT04015908 COMPLETED
Opioid Use
University of Utah
2019-08-01 PHASE4
NCT05438303 COMPLETED
Healthy Volunteers
AstraZeneca
2022-06-13 PHASE1
NCT03699293 TERMINATED
Rheumatoid Arthritis; Cardiovascular Diseases
Platelet and Thrombosis Research, LLC
2018-09-22 PHASE4
NCT04718649 UNKNOWN
Osteoarthritis
The Catholic University of Korea
2021-01
NCT04082715 WITHDRAWN
Chronic Back Pain
Second Affiliated Hospital of Wenzhou Medical University
2019-10 PHASE2
NCT02502006 TERMINATED
Healthy
University of Pennsylvania
2015-11 PHASE1
NCT05436678 COMPLETED
Pharmacokinetics
NeuroSense Therapeutics Ltd.
2022-07-26 PHASE1
NCT05648916 Enrolling by invitation
Heterotopic Ossification
McGill University Health Centre/Research Institute of the McGill University Health Centre
2022-08-02 --
NCT02389465 COMPLETED
Depression; Inflammation
University of Pennsylvania
2014-08 PHASE4
NCT05237297 COMPLETED
Drug Interaction Potentiation
Il-Yang Pharm. Co., Ltd.
2022-02-17 PHASE1
NCT03896113 UNKNOWN
Endometrium Cancer
Cliniques universitaires Saint-Luc- Université Catholique de Louvain
2019-11-13 PHASE2
NCT05077969 TERMINATED
2019 Novel Coronavirus Disease; 2019 Novel Coronavirus Infection; 2019-nCoV Disease; 2019-nCoV Infection; COVID-19; COVID-19 Pandemic; COVID-19 Virus Disease; COVID-19 Virus Infection; Covid19; Coronavirus Disease 2019; SARS-CoV2 Infection; SARS-CoV-2 Acute Respiratory Disease
Leidos Life Sciences
2021-12-29 PHASE2
NCT04429022 COMPLETED
Pain, Postoperative
State University of New York at Buffalo
2020-11-24 PHASE3
NCT04081389 COMPLETED
Anatomic Stage 0 Breast Cancer AJCC v8; Anatomic Stage I Breast Cancer AJCC v8; Anatomic Stage IA Breast Cancer AJCC v8; Anatomic Stage IB Breast Cancer AJCC v8; Anatomic Stage II Breast Cancer AJCC v8; Anatomic Stage IIA Breast Cancer AJCC v8; Anatomic Stage IIB Breast Cancer AJCC v8; Early-Stage Breast Carcinoma; Estrogen Receptor Negative; HER2/Neu Negative; Progesterone Receptor Negative; Prognostic Stage 0 Breast Cancer AJCC v8; Prognostic Stage I Breast Cancer AJCC v8; Prognostic Stage IA Breast Cancer AJCC v8; Prognostic Stage IB Breast Cancer AJCC v8; Prognostic Stage II Breast Cancer AJCC v8; Prognostic Stage IIA Breast Cancer AJCC v8; Prognostic Stage IIB Breast Cancer AJCC v8; Triple-Negative Breast Carcinoma
Roswell Park Cancer Institute
2019-12-06 PHASE1
NCT05232461 COMPLETED
Pharmacokinetics
NeuroSense Therapeutics Ltd.
2022-04-08 PHASE1
NCT05324995 COMPLETED
Postoperative Pain; Total Knee Arthroplasty
Isfahan University of Medical Sciences
2021-01-01 PHASE2
NCT05256823 Active not recruiting
To Evaluate the Safety and Efficacy of Celecoxib Plus Nucleos(t)Ide Analogues in Nucleos(t)Ide-treated Patients With Chronic Hepatitis B
Lai Wei|Beijing Tsinghua Chang Gung Hospital
2022-02-24 Phase 2
NCT04765644 COMPLETED
Healthy
Imperial College London
2021-06-10 PHASE4
NCT05994287 COMPLETED
Postoperative Pain, Acute
Federal State Budgetary Organization, Federal Center for Traumatology, Orthopedics and Arthroplasty
2021-01-01
NCT04090684 COMPLETED
ALS (Amyotrophic Lateral Sclerosis)
NeuroSense Therapeutics Ltd.
2019-12-09 PHASE1
NCT05324163 Completed
KNEE OSTEOARTHRITIS
Jiangsu XinChen-Techfields Pharma Co. LTD.
2021-09-29 Phase 3
NCT04505657 COMPLETED
IUCD Complication
Aswan University Hospital
2020-09-01
NCT03864575 UNKNOWN
Metastatic Cancer
Cliniques universitaires Saint-Luc- Université Catholique de Louvain
2019-08-15 PHASE2
NCT04447261 COMPLETED
Obesity
Boehringer Ingelheim
2020-06-30 PHASE1
NCT00503035 COMPLETED
Familial Adenomatous Polyposis
M.D. Anderson Cancer Center
2003-08-20 PHASE2
NCT03084536 COMPLETED
Breast Cancer; Breast Cancer Female; Cancer of Breast
Washington University School of Medicine
2017-06-07 PHASE2
NCT04165850 COMPLETED
Amyotrophic Lateral Sclerosis; ALS
NeuroSense Therapeutics Ltd.
2019-11-25 PHASE2
NCT02758782 COMPLETED
Ankylosing Spondylitis
Charite University, Berlin, Germany
2016-09 PHASE4
NCT03818919 COMPLETED
Rotator Cuff Tear
Henry Ford Health System
2019-01-22 PHASE2
NCT03625050 COMPLETED
Total Knee Replacement; Manipulation
Gachon University Gil Oriental Medical Hospital
2018-11-01 PHASE2
NCT03403634 COMPLETED
Metastatic Carcinoma in the Liver; Recurrent Colorectal Carcinoma; Stage IV Colorectal Cancer AJCC v7; Stage IVA Colorectal Cancer AJCC v7; Stage IVB Colorectal Cancer AJCC v7
Roswell Park Cancer Institute
2018-04-19 PHASE2
NCT03878524 TERMINATED
Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive; Anatomic Stage IV Breast Cancer AJCC v8; Anemia; Ann Arbor Stage III Hodgkin Lymphoma; Ann Arbor Stage III Non-Hodgkin Lymphoma; Ann Arbor Stage IV Hodgkin Lymphoma; Ann Arbor Stage IV Non-Hodgkin Lymphoma; Atypical Chronic Myeloid Leukemia, BCR-ABL1 Negative; Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive; Castration-Resistant Prostate Carcinoma; Chronic Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive; Hematopoietic and Lymphoid System Neoplasm; Locally Advanced Pancreatic Adenocarcinoma; Metastatic Breast Carcinoma; Metastatic Malignant Solid Neoplasm; Metastatic Pancreatic Adenocarcinoma; Myelodysplastic/Myeloproliferative Neoplasm With Ring Sideroblasts and Thrombocytosis; Myelodysplastic/Myeloproliferative Neoplasm, Unclassifiable; Primary Myelofibrosis; Recurrent Acute Lymphoblastic Leukemia; Recurrent Acute Myeloid Leukemia; Recurrent Chronic Lymphocytic Leukemia; Recurrent Chronic Myelogenous Leukemia, BCR-ABL1 Positive; Recurrent Hematologic Malignancy; Recurrent Hodgkin Lymphoma; Recurrent Myelodysplastic Syndrome; Recurrent Myelodysplastic/Myeloproliferative Neoplasm; Recurrent Myeloproliferative Neoplasm; Recurrent Non-Hodgkin Lymphoma; Recurrent Plasma Cell Myeloma; Recurrent Small Lymphocytic Lymphoma; Refractory Acute Lymphoblastic Leukemia; Refractory Acute Myeloid Leukemia; Refractory Chronic Lymphocytic Leukemia; Refractory Chronic Myelogenous Leukemia, BCR-ABL1 Positive; Refractory Chronic Myelomonocytic Leukemia; Refractory Hematologic Malignancy; Refractory Hodgkin Lymphoma; Refractory Malignant Solid Neoplasm; Refractory Myelodysplastic Syndrome; Refractory Myelodysplastic/Myeloproliferative Neoplasm; Refractory Non-Hodgkin Lymphoma; Refractory Plasma Cell Myeloma; Refractory Primary Myelofibrosis; Refractory Small Lymphocytic Lymphoma; Stage II Pancreatic Cancer AJCC v8; Stage III Pancreatic Cancer AJCC v8; Stage IV Pancreatic Cancer AJCC v8; Stage IV Prostate Cancer AJCC v8; Unresectable Pancreatic Adenocarcinoma
OHSU Knight Cancer Institute
2020-04-01 PHASE1
NCT04259333 UNKNOWN
Pain, Postoperative; Surgery--Complications; Opioid Analgesic Adverse Reaction; Opioid Use
Blake Raggio
2020-03-01 PHASE4
NCT03121963 WITHDRAWN
Pain Management
University of Alabama at Birmingham
2017-11-10 PHASE4
NCT04526197 COMPLETED
Wilson Disease
Alexion Pharmaceuticals, Inc.
2020-07-07 PHASE1
NCT03599453 COMPLETED
Triple -Negative Breast Cancer; Estrogen Receptor Negative; HER2/Neu Negative; Anatomic Stage IV Breast Cancer AJCC; Progesterone Receptor Negative
Roswell Park Cancer Institute
2019-01-09 EARLY_PHASE1
NCT04490434 UNKNOWN
Healthy Male Volunteers
Daewoong Pharmaceutical Co. LTD.
2020-06-19 PHASE1
NCT03949673 TERMINATED
Osteoarthritis, Knee; Osteoarthritis, Hip
Regeneron Pharmaceuticals
2019-04-08 PHASE2
NCT02876094 TERMINATED
Spinal Muscular Atrophy (SMA)
Hugh McMillan
2019-01-29 PHASE2
NCT04639804 COMPLETED
Healthy
HK inno.N Corporation
2020-06-06 PHASE1
NCT02827487 UNKNOWN
Pain
Cairo University
2016-07-01 PHASE4
NCT04526197 Completed
Wilson Disease
Alexion Pharmaceuticals Inc.
2020-07-07 Phase 1
NCT03820193 COMPLETED
Meniscus Disorder; Narcotic Use
Henry Ford Health System
2019-01-22 EARLY_PHASE1
NCT04020588 UNKNOWN
Schizophrenia
Hospital Psiquiatrico Infantil Dr. Juan N. Navarro, Mexico
2019-02-25 PHASE4
NCT03850587 COMPLETED
Osteoarthritis, Knee
Yooyoung Pharmaceutical Co., Ltd.
2018-08-30 PHASE2
NCT05547659 COMPLETED
Compare Unimodal and Multimodal Analgesics
October 6 University
2019-01-01 PHASE1; PHASE2
NCT01313429 TERMINATED
Sarcoma; Melanoma; Epithelial Malignancies; Pleural Malignancies
National Cancer Institute (NCI)
2011-03-04 PHASE1
NCT04342065 COMPLETED
Post-Operative Pain
South Egypt Cancer Institute
2019-01-01 PHASE2; PHASE3
NCT03818932 COMPLETED
Anterior Cruciate Ligament Injury
Henry Ford Health System
2019-01-22 PHASE2; PHASE3
NCT03825809 RECRUITING
Narcotic Use
Henry Ford Health System
2019-01-22 PHASE2; PHASE3
NCT02160301 WITHDRAWN
Post Operative Pain Control
University of North Carolina, Chapel Hill
2017-11 PHASE4
NCT04374981 COMPLETED
Food-drug Interaction
Damanhour University
2019-07-01 PHASE2
NCT03885596 COMPLETED
Pain
Concentric Analgesics
2019-03-25 PHASE2
NCT03464552 COMPLETED
Colposcopy
Cairo University
2018-04-15 PHASE4
NCT02845336 TERMINATED
Thyroid Eye Disease
Johns Hopkins University
2017-03-05 PHASE2
NCT03541655 COMPLETED
Total Knee Replacement; Postoperative Pain
Arthritis Innovation Corporation
2018-05-04 PHASE2
NCT03570554 COMPLETED
Osteoarthritis, Knee
Bayer
2018-06-29 PHASE2
NCT02725411 COMPLETED
Low Back Pain
Pfizer
2016-05-26 PHASE3
NCT03586934 WITHDRAWN
Shoulder Pain; Opioid Use
Rush University Medical Center
2018-06-01 PHASE3
NCT02667730 COMPLETED
Ligament Injury
Canadian Department of National Defence
2015-06 PHASE4
NCT03337607 COMPLETED
Low Back Pain
First Affiliated Hospital of Zhejiang University
2017-11-13
NCT02362529 COMPLETED
Major Depressive Disorder
Centre for Addiction and Mental Health
2015-02 EARLY_PHASE1
NCT02429427 COMPLETED
Breast Cancer
Imperial College London
2005-12 PHASE3
NCT03059238 COMPLETED
Liver Cancer; Pain Postoperative
Sun Yat-sen University
2016-09 PHASE3
NCT02151448 COMPLETED
Malignant Neoplasm of Pancreas Metastatic to Peritoneal Surface; Malignant Peritoneal Mesothelioma; Peritoneal Carcinomatosis
David Bartlett
2014-07 PHASE1; PHASE2
NCT03672162 COMPLETED
Total Abdominal Hysterectomy ,Pain , Acute Postoperative,Gabapentin , Celecoxib
Department of Medical Services Ministry of Public Health of Thailand
2019-02-01
NCT02726659 TERMINATED
Bipolar Disorder; Postpartum Depression
London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
2016-05 PHASE3
NCT03404479 UNKNOWN
Knee Osteoarthritis
Whan-Seok Choi
2018-01-25 PHASE4
NCT02280694 COMPLETED
Colorectal Cancer
HaEmek Medical Center, Israel
2015-01 PHASE2
NCT02790203 UNKNOWN
Prevention of Post Operative Ileus
Sheba Medical Center
2016-06
NCT02703363 COMPLETED
Depression; Bipolar Disorder; Bipolar Depression; Mood Disorders
Pakistan Institute of Living and Learning
2016-08 PHASE3
NCT02484664 COMPLETED
Lymphangioleiomyomatosis (LAM)
Brigham and Women's Hospital
2016-06-15 PHASE2
NCT02770378 COMPLETED
Glioblastoma
University of Ulm
2016-11 PHASE1; PHASE2
NCT02260336 UNKNOWN
Rheumatic Pain
Chengdu PLA General Hospital
2014-10
NCT03554772 COMPLETED
Acute Pain
Dr. Reddy's Laboratories Limited
2018-06-19 PHASE2
NCT02934191 COMPLETED
Tonsillectomy
Children's Hospital of Philadelphia
2016-06 PHASE2
NCT02688400 COMPLETED
Osteoarthritis; Osteoarthritis, Knee
TRB Chemedica International SA
2016-05 PHASE3
NCT03190603 COMPLETED
Spondylarthropathies; Magnetic Resonance Imaging
Armed Forces Capital Hospital, Republic of Korea
2018-06-01 PHASE4
NCT02615574 WITHDRAWN
Metastatic Colorectal Cancer
Pawel Kalinski
2016-03 PHASE2
NCT03822520 COMPLETED
Qt Interval, Variation in
Samsung Medical Center
2017-06-30 PHASE1
NCT02108366 COMPLETED
Influenza, Human
The University of Hong Kong
2014-03 PHASE3
NCT02987920 TERMINATED
Pain, Postoperative
University of Southern California
2017-01 PHASE4
NCT01479829 COMPLETED
Bipolar Depression
Loyola University
2011-03-23 PHASE4
NCT03108482 COMPLETED
Acute Post-surgical Pain
Esteve Pharmaceuticals, S.A.
2017-03-14 PHASE3
NCT02979197 COMPLETED
Hypertension
Kitov Pharma Ltd
2016-11-03 PHASE3
NCT03067194 COMPLETED
Osteoarthritis Hand
Chong Kun Dang Pharmaceutical
2016-12-27 PHASE4
NCT02703259 COMPLETED
Pain, Postoperative
Christiana Care Health Services
2016-06 PHASE4
NCT01111591 UNKNOWN
Bile Duct Cancer; Pancreatic Cancer
Seoul National University Hospital
2008-11 PHASE4
NCT02759198 COMPLETED
Knee Osteoarthritis
Yuhan Corporation
2016-05-02 PHASE2
NCT02711579 COMPLETED
Electrophysiologic Property of Brain
Seoul National University Hospital
2016-05 PHASE1
NCT02839694 WITHDRAWN
Neoplasm Metastasis; Sarcoma; Neoplasms, Germ Cell and Embryonal; Melanoma
National Cancer Institute (NCI)
2016-07-07 PHASE1
NCT02736019 UNKNOWN
Hysteroscopy
Cairo University
2016-06 PHASE3
NCT02736071 UNKNOWN
Hysteroscopy
Cairo University
2016-06 PHASE3
NCT02638896 UNKNOWN
Ankylosing Spondylitis
Zhixiang Huang
2016-01 PHASE4
NCT02268825 TERMINATED
Advanced GI Cancer
University of Utah
2015-01-23 PHASE1
NCT01041781 TERMINATED
Lung Cancer
Alliance for Clinical Trials in Oncology
2010-02 PHASE3
NCT00223691 COMPLETED
Autonomic Failure; Orthostatic Hypotension
Vanderbilt University
2002-03 PHASE1
NCT00153673 COMPLETED
Arthritis; Gastric Ulcer
Chinese University of Hong Kong
2001-02 PHASE3
NCT03523832 COMPLETED
Acute Pain
Fakultas Kedokteran Universitas Indonesia
2015-07-01 PHASE2
NCT02307305 UNKNOWN
Neuropathic Pain
Hanyang University Seoul Hospital
2014-08 PHASE2
NCT02537925 UNKNOWN
Nasopharyngeal Carcinoma
Changjie Huang
2014-01 PHASE3
NCT02739204 UNKNOWN
Oral Squamous Cell Carcinoma
China Medical University Hospital
2013-11 PHASE2
NCT02131012 TERMINATED
Inflammation
Vanderbilt University
2015-06 PHASE1
NCT02198924 COMPLETED
Pain; Inflammation
Peking Union Medical College Hospital
2014-12 PHASE4
NCT01425476 COMPLETED
Breast Cancer
Hartford Hospital
2008-07 PHASE1; PHASE2
NCT01769625 COMPLETED
Biomarker Change Linked to Breast Cancer
Hartford Hospital
2009-01 PHASE1; PHASE2
NCT02600247 UNKNOWN
Osteoarthritis
The Catholic University of Korea
2015-11
NCT02301234 COMPLETED
Osteoarthritis; Pain
Janssen Research & Development, LLC
2015-03-25 PHASE3
NCT01729923 TERMINATED
Recurrent Colon Carcinoma; Recurrent Rectal Carcinoma; Stage IVA Colon Cancer; Stage IVA Rectal Cancer; Stage IVB Colon Cancer; Stage IVB Rectal Cancer
University of Washington
2013-03 PHASE2
NCT02961998 COMPLETED
Hepatocellular Carcinoma
Sun Yat-sen University
2015-07 PHASE4
NCT03331315 COMPLETED
Pain, Postoperative
Michael Ulm, MD
2013-09-01 PHASE2
NCT01258868 TERMINATED
Mesolthelioma; Esophageal Cancer; Lung Cancer; Thoracic Sarcomas; Thymoma
National Cancer Institute (NCI)
2010-12-01 PHASE1
NCT01341496 TERMINATED
Sarcoma; Melanoma; Epithelial Malignancies; Pleural Malignancy
National Cancer Institute (NCI)
2011-04-18 PHASE1
NCT00346216 COMPLETED
Arthritis, Rheumatoid
Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
2006-10-04 PHASE4
NCT02351934 COMPLETED
Colorectal Disorders
Mayo Clinic
2015-02 PHASE4
NCT01705106 TERMINATED
Unspecified Adult Solid Tumor, Protocol Specific
University of Chicago
2012-08-29 PHASE1
NCT02602509 COMPLETED
Tuberculosis
National University Hospital, Singapore
2015-11 PHASE1
NCT01796951 COMPLETED
Tobacco Use Disorder; Smoking
Vanderbilt University
2013-02 EARLY_PHASE1
NCT02779166 COMPLETED
Hip Labral Tears
Northwestern University
2012-08
NCT02355236 UNKNOWN
Osteoarthritis
Severance Hospital
2015-02 PHASE4
NCT02172040 COMPLETED
Hypertension
Kitov Pharmaceuticals, Ltd.
2014-06-26 PHASE3
NCT02413203 COMPLETED
Healthy
University of Pennsylvania
2015-03
NCT02850211 COMPLETED
Rotator Cuff Tear
Seoul National University Bundang Hospital
2011-09 PHASE4
NCT02079727 COMPLETED
Knee Osteoarthritis
IBSA Institut Biochimique SA
2014-06-12 PHASE3
NCT01934933 COMPLETED
Ankylosing Spondylitis
Sun Yat-sen University
2014-09-24 PHASE4
NCT01285817 COMPLETED
Survival Without Progression
Assistance Publique Hopitaux De Marseille
2011-01-12 PHASE2
NCT00447759 COMPLETED
Osteoarthritis; Rheumatoid Arthritis
University of Dundee
2007-06 PHASE4
NCT02401295 COMPLETED
Relapsed Multiple Myeloma
University of Iowa
2015-05 PHASE1
NCT02502500 COMPLETED
Healthy Volunteers
Akebia Therapeutics
2015-07 PHASE1
NCT02408146 UNKNOWN
Pain, Postoperative
First Affiliated Hospital of Harbin Medical University
2014-01
NCT02054104 TERMINATED
Thoracic Sarcomas; Thorasic Cancers; Cancers of Non-thoracic Origin With Metastases to the Lungs or Pleura; Sarcoma; Melanoma
National Cancer Institute (NCI)
2014-09-03 PHASE1; PHASE2
NCT01631669 UNKNOWN
Ossification, Heterotopic
Walter Reed National Military Medical Center
2012-05
NCT01838044 TERMINATED
Chronic Low Back Pain With a Neuropathic Component
Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
2013-10 PHASE4
NCT01143545 TERMINATED
Lung Cancer; Esophageal Cancer; Malignant Pleural Mesothelioma; Sarcoma; Thymic Carcinoma
National Cancer Institute (NCI)
2010-12-07 PHASE1
NCT00159484 COMPLETED
Colon Cancer; Colorectal Cancer
University of Southern California
2004-10-12 PHASE1; PHASE2
NCT00571701 COMPLETED
Recurrent Respiratory Papillomatosis
Northwell Health
2008-02 PHASE2
NCT01709656 COMPLETED
Ankylosing Spondylitis
Sun Yat-sen University
2012-03
NCT02179645 COMPLETED
Healthy
Glenmark Pharmaceuticals Ltd. India
2014-05 PHASE1
NCT01503385 UNKNOWN
Lung Cancer
Chinese Academy of Medical Sciences
2011-12 PHASE2
NCT01220973 COMPLETED
Prostate Cancer
Rutgers, The State University of New Jersey
2009-02 PHASE2
NCT02071303 COMPLETED
Pain
Cairo University
2014-05 PHASE2
NCT00153660 COMPLETED
Arthritis; Cardiovascular Diseases; Cerebrovascular Disorders
Chinese University of Hong Kong
2005-06 PHASE3
NCT01768520 COMPLETED
Knee Osteoarthritis
Hanlim Pharm. Co., Ltd.
2012-07-02 PHASE3
NCT00104767 COMPLETED
Lung Cancer
Jonsson Comprehensive Cancer Center
2009-01 PHASE1
NCT02084511 COMPLETED
Pain, Postoperative
Boehringer Ingelheim
2014-03 PHASE1
NCT01354145 COMPLETED
Knee Osteoarthritis
Bioiberica
2011-06 PHASE3
NCT00112502 COMPLETED
Brain and Central Nervous System Tumors; Glioblastoma Multiforme
M.D. Anderson Cancer Center
2005-09 PHASE2
NCT01901679 COMPLETED
Obesity
Rockefeller University
2013-07 EARLY_PHASE1
NCT02037165 COMPLETED
Healthy
Boehringer Ingelheim
2014-01-21 PHASE1
NCT01968070 COMPLETED
Healthy Volunteers
Eli Lilly and Company
2013-10 PHASE1
NCT01067989 TERMINATED
Chemotherapy; Breast Cancer, Metastatic
HaEmek Medical Center, Israel
2010-03 PHASE2
NCT01881048 COMPLETED
Stage IA Breast Cancer; Stage IB Breast Cancer; Stage II Breast Cancer; Stage IIIA Breast Cancer; Stage IIIB Breast Cancer; Stage IIIC Breast Cancer; Stage IV Breast Cancer
University of Colorado, Denver
2009-12-08 EARLY_PHASE1
NCT01765296 COMPLETED
Localized Primary Osteoarthritis of Hip; Localized Primary Osteoarthritis of Knee
CrystalGenomics, Inc.
2013-03 PHASE3
NCT01849055 COMPLETED
Healthy Volunteers
Eli Lilly and Company
2013-05 PHASE1
NCT01756989 COMPLETED
Brainstem Glioma
Helsinki University Central Hospital
2005-01 PHASE2
NCT01668680 TERMINATED
Colorectal Cancer Metastatic
HaEmek Medical Center, Israel
2012-09 PHASE2
NCT00520845 TERMINATED
Lung Cancer
Vanderbilt-Ingram Cancer Center
2007-10 PHASE2
NCT02343614 COMPLETED
Non Muscle Invasive Bladder Cancer
Azienda Ospedaliero-Universitaria Consorziale Policlinico di Bari
2003-03 PHASE2
NCT00585312 TERMINATED
Adenomatous Polyposis Coli
Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
2006-09 PHASE3
NCT01678313 COMPLETED
Benign Prostatic Hyperplasia
Buddhist Tzu Chi General Hospital
2012-08 PHASE2
NCT01555073 TERMINATED
Uterine Fibroids; Uterine Artery Embolization
Northwestern University
2011-10 PHASE4
NCT01623921 UNKNOWN
Blunt Chest Trauma; Acute Respiratory Distress Syndrome
Tel-Aviv Sourasky Medical Center
2012-08
NCT00780325 TERMINATED
Healthy Volunteers
University of Pennsylvania
2008-10 PHASE1
NCT01175772 TERMINATED
Ovarian Carcinoma
HaEmek Medical Center, Israel
2010-08 PHASE2
NCT01186887 COMPLETED
Pain
Ottawa Hospital Research Institute
2009-02
NCT01632566 TERMINATED
Healthy Volunteers
Eli Lilly and Company
2012-06 PHASE1
NCT01554163 COMPLETED
Osteoarthritis of the Knee
Organon and Co
2012-03 PHASE3
NCT00357500 COMPLETED
Central Nervous System Tumor, Pediatric; Leukemia; Lymphoma; Neuroblastoma; Sarcoma; Unspecified Childhood Solid Tumor, Protocol Specific
Dana-Farber Cancer Institute
2005-01 PHASE2
NCT01323595 TERMINATED
Pain
Weill Medical College of Cornell University
2011-01
NCT00400374 COMPLETED
Head and Neck Cancer
Emory University
2007-08 PHASE1
NCT00250835 TERMINATED
Rectal Cancer
New Mexico Cancer Research Alliance
2005-04 PHASE2
NCT00807846 COMPLETED
Arthritis, Juvenile Rheumatoid
Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
2009-09 PHASE4
NCT00314262 COMPLETED
Precancerous Conditions
Emory University
2006-10 PHASE1; PHASE2
NCT00698204 COMPLETED
Oral Mucositis
UConn Health
2003-07 PHASE2
NCT00081263 COMPLETED
Cervical Carcinoma; Cervical Intraepithelial Neoplasia Grade 2/3; Stage 0 Cervical Cancer
Gynecologic Oncology Group
2005-06 PHASE2
NCT01632579 COMPLETED
Healthy Volunteers
Eli Lilly and Company
2012-06 PHASE1
NCT00849966 COMPLETED
Tonsillectomy; Adenotonsillectomy; Pain, Postoperative
Children's Hospital of Eastern Ontario
2009-08 PHASE2
NCT01021215 COMPLETED
Tobacco Use Disorder
National Cancer Institute (NCI)
2010-05 PHASE1; PHASE2
NCT01549743 COMPLETED
Healthy Male Volunteers
Hanlim Pharm. Co., Ltd.
2012-05-09 PHASE1
NCT01543685 COMPLETED
Other Acute Postoperative Pain
Iroko Pharmaceuticals, LLC
2012-02 PHASE3
NCT00931203 COMPLETED
Locally Advanced Rectal Cancer
National Health Research Institutes, Taiwan
2008-07 PHASE2
NCT00198081 TERMINATED
Pancreas Neoplasms
Indiana University
2005-09 PHASE2
NCT00687388 WITHDRAWN
Benign Prostatic Hyperplasia
Samsung Medical Center
2008-05 PHASE4
NCT01462435 COMPLETED
Other Acute Postoperative Pain
Iroko Pharmaceuticals, LLC
2011-10 PHASE3
NCT00551889 COMPLETED
Unspecified Adult Solid Tumor, Protocol Specific
City of Hope Medical Center
2001-09 PHASE1
NCT00551005 COMPLETED
Unspecified Adult Solid Tumor, Protocol Specific
City of Hope Medical Center
2001-12 PHASE1
NCT02695745 COMPLETED
Pain
Purdue Pharma LP
2011-09 PHASE1
NCT00135018 COMPLETED
Breast Cancer
Organisation for Oncology and Translational Research
2006-02 PHASE2
NCT01280006 COMPLETED
Obstructive Sleep Apnea; Hypertension; Cardiovascular Diseases; Stroke
University of Calgary
2011-01 PHASE1; PHASE2
NCT01341405 COMPLETED
Osteoarthritis
CrystalGenomics, Inc.
2011-04 PHASE2
NCT01860833 COMPLETED
Knee Osteoarthritis
University of Catanzaro
2010-04 PHASE4
NCT01304069 COMPLETED
Healthy
Turku University Hospital
2011-01 PHASE1
NCT00808743 COMPLETED
Familial Adenomatous Polyposis; Duodenal Neoplasms; Duodenal Polyps
Radboud University Medical Center
2009-05 PHASE2; PHASE3
NCT01284504 TERMINATED
Colorectal Cancer; Colon Cancer
Stanford University
2011-01
NCT00538031 COMPLETED
Fallopian Tube Cancer; Peritoneal Cavity Cancer; Recurrent Ovarian Epithelial Cancer
City of Hope Medical Center
2003-12-22 PHASE2
NCT00152828 COMPLETED
Cervix Neoplasms
University Health Network, Toronto
2001-02 PHASE1; PHASE2
NCT00970502 COMPLETED
Cancer of the Pharynx; Cancer of the Larynx; Cancer of the Neck; Paranasal Sinus Neoplasms; Cancer of the Head
Johnny Kao
2007-02 PHASE1; PHASE2
NCT00373685 COMPLETED
Osteoarthritis
Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
2006-10 PHASE4
NCT01158534 COMPLETED
Renal Cell Cancer; Stage IV Renal Cell Cancer
Case Comprehensive Cancer Center
2006-03 PHASE2
NCT00504660 COMPLETED
Anaplastic Glioma of Brain; Glioblastoma Multiforme; Brain Cancer
M.D. Anderson Cancer Center
2003-09 PHASE2
NCT01062113 COMPLETED
Pain
Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
2010-04 PHASE2
NCT00177866 TERMINATED
Crohn's Disease
University of Pittsburgh
2003-12 PHASE4
NCT00581685 COMPLETED
Osteoarthritis
Sunnybrook Health Sciences Centre
2008-01 PHASE3
NCT00762463 COMPLETED
Ankylosing Spondylitis
Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
2009-07 PHASE3
NCT00108186 WITHDRAWN
Non-Small-Cell Lung Carcinoma
US Department of Veterans Affairs
2004-10 PHASE1
NCT00300729 UNKNOWN
Non-Small Cell Lung Cancer
University Hospital, Linkoeping
2006-05 PHASE3
NCT00994461 COMPLETED
Healthy Volunteers
Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
2009-11 PHASE4
NCT00070057 COMPLETED
Stage I Breast Cancer; Stage II Breast Cancer; Stage IIIA Breast Cancer; Stage IIIB Breast Cancer; Stage IIIC Breast Cancer
National Cancer Institute (NCI)
2003-04 PHASE1
NCT00894790 TERMINATED
Pain
Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
2009-11 PHASE4
NCT00442676 WITHDRAWN
Preeclampsia
Virginia Commonwealth University
2009-06 PHASE2
NCT00291694 COMPLETED
Breast Cancer
Carol Fabian, MD
2003-04 PHASE2
NCT00964431 COMPLETED
Dental Pain
Iroko Pharmaceuticals, LLC
2009-08 PHASE2
NCT00589186 UNKNOWN
Head and Neck Cancer
National Cancer Centre, Singapore
2007-11 PHASE2
NCT00549549 COMPLETED
Arthritis, Gouty
Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
2008-02 PHASE3
NCT00985439 COMPLETED
Dental Pain
Iroko Pharmaceuticals, LLC
2009-09 PHASE2
NCT00520338 COMPLETED
Postoperative Pain; Thyroidectomy; Cyclooxygenase 2 Inhibitors
Mahidol University
2007-08 PHASE4
NCT00976716 COMPLETED
Pain
Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
2009-09 PHASE3
NCT01344213 COMPLETED
Postoperative Pain Management; Total Knee Arthroplasty
Chulalongkorn University
2008-07 PHASE4
NCT00925106 COMPLETED
Healthy Volunteers
Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
2009-07 PHASE1
NCT00598234 COMPLETED
Osteoarthritis
National Taiwan University Hospital
2006-09 PHASE4
NCT00665457 TERMINATED
Breast Cancer
University of Nebraska
2004-04-15 PHASE2
NCT00088972 TERMINATED
Breast Cancer
SWOG Cancer Research Network
2004-11 PHASE2
NCT00484718 TERMINATED
Osteoarthritis
Pfizer
2008-01-17 PHASE4
NCT00450736 COMPLETED
Childhood Malignant Fibrous Histiocytoma of Bone; Sarcoma
University of Miami
2004-03 PHASE1
NCT00141102 COMPLETED
Osteoarthritis; Arthritis, Rheumatoid
Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
2005-10 PHASE4
NCT00526214 COMPLETED
Intracerebral Hemorrhage
Seoul National University Hospital
2007-10
NCT00813241 COMPLETED
Healthy Volunteers
Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
2009-01 PHASE1
NCT00188565 COMPLETED
Colorectal Neoplasms
University Health Network, Toronto
2004-03 PHASE1; PHASE2
NCT00033371 COMPLETED
Colorectal Cancer; Familial Adenomatous Polyposis
National Cancer Institute (NCI)
2001-12-13 PHASE2
NCT01017380 COMPLETED
Anterior Cruciate Ligament Injury
Prince of Songkla University
2008-01 PHASE3
NCT00624559 COMPLETED
Hypertension
University of Delaware
2008-02 PHASE4
NCT00088959 COMPLETED
Recurrent Non-small Cell Lung Cancer; Stage IIIB Non-small Cell Lung Cancer; Stage IV Non-small Cell Lung Cancer
National Cancer Institute (NCI)
2003-12 PHASE1
NCT00290680 COMPLETED
Unspecified Adult Solid Tumor, Protocol Specific
Medical University of South Carolina
2005-03 PHASE1
NCT00664560 COMPLETED
Osteoarthritis
POZEN
2008-04 PHASE3
NCT00665431 COMPLETED
Osteoarthritis
POZEN
2008-04 PHASE3
NCT00546507 COMPLETED
Osteoarthritis
Mika Pharma GmbH
2007-10 PHASE3
NCT00101686 COMPLETED
Colorectal Neoplasms
Pfizer
2003-02 PHASE3
NCT00546832 COMPLETED
Osteoarthritis
Mika Pharma GmbH
2007-10 PHASE3
NCT00662558 COMPLETED
Low Back Pain
Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
2008-01 PHASE3
NCT00585156 TERMINATED
Bone Ingrowth; Pain
University of Utah
2008-06 EARLY_PHASE1
NCT00527982 TERMINATED
Head and Neck Cancer; Lung Cancer
M.D. Anderson Cancer Center
2005-09 PHASE2
NCT00729495 COMPLETED
Healthy Volunteer
POZEN
2008-07 PHASE1
NCT00304317 WITHDRAWN
Ureteral Calculi
University of Minnesota
2006-03 PHASE4
NCT00466505 COMPLETED
Colorectal Cancer
Vanderbilt-Ingram Cancer Center
2005-05 PHASE2
NCT00056082 COMPLETED
Breast Cancer
University of Kansas Medical Center
2003-01 PHASE2
NCT00700687 COMPLETED
Healthy
POZEN
2008-06 PHASE1
NCT00663767 COMPLETED
Dental Pain
Pfizer
2008-04-07 PHASE2
NCT00582660 COMPLETED
Colorectal Adenoma; Colorectal Carcinoma
University of Alabama at Birmingham
2001-12 PHASE2
NCT00099047 COMPLETED
Monoclonal Gammopathy of Undetermined Significance; Multiple Myeloma; Smoldering Multiple Myeloma
National Cancer Institute (NCI)
2004-11 PHASE2
NCT00446797 COMPLETED
Ankle Sprain
Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
2007-05 PHASE4
NCT00038103 COMPLETED
Breast Neoplasms
Pfizer
2002-01 PHASE2
NCT00055978 COMPLETED
Lung Cancer
University of California, Los Angeles
2002-10 PHASE2
NCT00778193 COMPLETED
Gastroduodenal Ulcer
Research Associates of New York, LLP
2007-10 PHASE4
NCT00139776 COMPLETED
Osteoarthritis, Knee; Osteoarthritis, Hip
Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
2005-07 PHASE4
NCT00597415 UNKNOWN
Osteoarthritis of the Knee
University Hospitals Cleveland Medical Center
2004-12 PHASE2
NCT00581971 COMPLETED
Cancer
University of Alabama at Birmingham
2002-09 PHASE1; PHASE2
NCT00424294 TERMINATED
Arthritis, Rheumatoid
Pfizer
2006-06 PHASE2
NCT00402987 COMPLETED
Pharyngitis
Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
2006-12-04 PHASE3
NCT00201773 COMPLETED
Breast Cancer
Ohio State University Comprehensive Cancer Center
2003-07 PHASE2
NCT00068653 COMPLETED
Lung Cancer
Barbara Ann Karmanos Cancer Institute
2003-06 PHASE2
NCT01124435 COMPLETED
Ovarian Neoplasms
Catholic University of the Sacred Heart
2003-10 PHASE2
NCT00081848 COMPLETED
Liver Neoplasms
National Cancer Institute (NCI)
2004-04-20 PHASE1
NCT00603759 UNKNOWN
Head and Neck Cancer
Tehran University of Medical Sciences
2006-04 PHASE3
NCT00256321 TERMINATED
Gastric Carcinoma; Gastroesophageal Junction Carcinoma
University of California, Irvine
2004-10 PHASE2
NCT01695226 COMPLETED
Breast Neoplasms; Breast Cancer
Maastricht University Medical Center
2004-02 PHASE2
NCT00981201 COMPLETED
Smoking; Prevention
M.D. Anderson Cancer Center
2001-11 PHASE3
NCT00007189 COMPLETED
Alzheimer Disease
Seattle Institute for Biomedical and Clinical Research
2001-01 PHASE3
NCT00039390 COMPLETED
Unspecified Adult Solid Tumor, Protocol Specific
National Cancer Institute (NCI)
2002-04 PHASE1
NCT00141193 COMPLETED
Colorectal Adenoma
Pfizer
2001-02 PHASE3
NCT00258232 COMPLETED
Colorectal Cancer
Barbara Ann Karmanos Cancer Institute
2002-01 PHASE2
NCT00212108 COMPLETED
Nasopharyngeal Carcinoma
National University Hospital, Singapore
2003-11 PHASE1; PHASE2
NCT00057980 COMPLETED
Liver Cancer
Northwestern University
2002-10 PHASE1; PHASE2
NCT00070486 COMPLETED
Lung Cancer
Alliance for Clinical Trials in Oncology
2003-12 PHASE2
NCT00058006 COMPLETED
Head and Neck Cancer; Lung Cancer
Northwestern University
2002-09 PHASE2
NCT00290901 COMPLETED
Back Pain
Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
2006-03 PHASE4
NCT00177853 TERMINATED
Pancreatic Cancer
University of Pittsburgh
2006-12 PHASE1
NCT00520091 COMPLETED
Esophageal Cancer
UNC Lineberger Comprehensive Cancer Center
2005-03 PHASE2
NCT00062179 COMPLETED
Lung Cancer
Jonsson Comprehensive Cancer Center
2003-03 PHASE2
NCT00596219 COMPLETED
SQUAMOUS CELL CARCINOMA
Memorial Sloan Kettering Cancer Center
2003-12
NCT00165451 COMPLETED
Neoplasms
Dana-Farber Cancer Institute
2001-06 PHASE2
NCT00154219 COMPLETED
Osteoarthritis, Hip
Novartis
2004-11 PHASE3
NCT00136487 COMPLETED
Prostate Cancer
Dana-Farber Cancer Institute
2002-10 PHASE2; PHASE3
NCT01762891 COMPLETED
Antiphospholipid Antibody Syndrome
Hospital Universitario Pedro Ernesto
2003-03
NCT00061906 COMPLETED
Head and Neck Cancer
Ohio State University Comprehensive Cancer Center
2003-01 PHASE2
NCT00348491 COMPLETED
Pain
Novartis Pharmaceuticals
2006-02 PHASE4
NCT00685568 COMPLETED
Colorectal Cancer; Precancerous Condition
M.D. Anderson Cancer Center
2002-11-21 PHASE1
NCT00087256 TERMINATED
Colorectal Cancer
NSABP Foundation Inc
2004-07 PHASE3
NCT00005094 COMPLETED
Colon Cancer; Rectal Cancer
National Cancer Institute (NCI)
2000-03 PHASE3
NCT00084578 WITHDRAWN
Bladder Cancer
Fox Chase Cancer Center
2004-03
NCT00137410 COMPLETED
Osteoarthritis,Knee
Pfizer
2002-11 PHASE3
NCT00653250 COMPLETED
Lung Cancer
Vanderbilt-Ingram Cancer Center
2000-12
NCT00006124 COMPLETED
Recurrent Bladder Cancer
National Cancer Institute (NCI)
2000-06 PHASE2; PHASE3
NCT00081224 TERMINATED
Colorectal Cancer
Alliance for Clinical Trials in Oncology
2004-12 PHASE2
NCT00183807 TERMINATED
Esophageal Cancer
University of Southern California
2003-10 PHASE2
NCT00062101 COMPLETED
Recurrent Non-small Cell Lung Cancer; Stage IIIB Non-small Cell Lung Cancer; Stage IV Non-small Cell Lung Cancer
National Cancer Institute (NCI)
2004-01 PHASE2
NCT00014404 COMPLETED
Head and Neck Cancer
Memorial Sloan Kettering Cancer Center
2000-10 PHASE2
NCT00027976 WITHDRAWN
Precancerous Condition
University of Alabama at Birmingham
2001-12 PHASE2; PHASE3
NCT00145301 COMPLETED
Osteoarthritis
Novartis
2004-09 PHASE3
NCT00065169 COMPLETED
Alzheimer Disease; Dementia
University of California, Los Angeles
2000-11
NCT00085163 COMPLETED
Colorectal Cancer
European Organisation for Research and Treatment of Cancer - EORTC
2004-03 PHASE3
NCT00194090 COMPLETED
Knee Osteoarthritis
University Hospitals Cleveland Medical Center
2004-06 PHASE4
NCT00030407 COMPLETED
Lung Cancer
Barbara Ann Karmanos Cancer Institute
2001-10 PHASE2
NCT00005878 COMPLETED
Esophageal Cancer
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
2000-07 PHASE2
NCT00045591 TERMINATED
Breast Cancer
Alliance for Clinical Trials in Oncology
2003-02 PHASE2
NCT00047281 COMPLETED
Brain and Central Nervous System Tumors
Dana-Farber Cancer Institute
2004-03 PHASE2
NCT00068432 COMPLETED
Pancreatic Cancer
M.D. Anderson Cancer Center
2003-12 PHASE2
NCT00009230 COMPLETED
Memory Disorders
University of California, Los Angeles
2000-06 PHASE3
NCT00882388 COMPLETED
Healthy
Seoul National University Hospital
2005-03 PHASE4
NCT00073970 TERMINATED
Prostate Cancer
UNC Lineberger Comprehensive Cancer Center
2003-04 PHASE2
NCT00068770 TERMINATED
Brain and Central Nervous System Tumors
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
2003-10 PHASE2
NCT00084448 TERMINATED
Ovarian Cancer; Primary Peritoneal Cavity Cancer
Gynecologic Oncology Group
2004-04 PHASE2
NCT00494338 TERMINATED
Metastatic Prostate Cancer
Sanofi
2004-11 PHASE2
NCT00084370 WITHDRAWN
brca1 Mutation Carrier; brca2 Mutation Carrier; Ovarian Cancer
University of Alabama at Birmingham
2002-06
NCT00052611 COMPLETED
Head and Neck Cancer
Dana-Farber Cancer Institute
2002-06 PHASE2
NCT00047294 COMPLETED
Brain and Central Nervous System Tumors
Dana-Farber Cancer Institute
2001-04 PHASE2
NCT00092781 COMPLETED
Osteoarthritis
Organon and Co
2004-03-01 PHASE3
NCT00092768 COMPLETED
Osteoarthritis
Organon and Co
2004-03-01 PHASE3
NCT00022399 COMPLETED
Prostate Cancer
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
2002-04-25 PHASE2
NCT02840162 TERMINATED
Adenocarcinoma of the Prostate; Prostate Cancer
OHSU Knight Cancer Institute
2001-05 PHASE2
NCT00064181 COMPLETED
Colorectal Cancer
European Organisation for Research and Treatment of Cancer - EORTC
2003-05 PHASE3
NCT00643799 COMPLETED
Osteoarthritis, Knee
Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
2004-03 PHASE4
NCT00101335 COMPLETED
Head and Neck Cancer; Precancerous Condition
Fox Chase Cancer Center
2003-11 PHASE2
NCT00023660 COMPLETED
Cervical Cancer
Radiation Therapy Oncology Group
2001-08 PHASE1; PHASE2
NCT00073866 COMPLETED
Lung Cancer
Northwestern University
2003-06 PHASE1; PHASE2
NCT00475800 COMPLETED
Osteoarthritis
Novartis
2004-01 PHASE3
NCT02090933 COMPLETED
No Evidence of Disease
National Cancer Institute (NCI)
2004-03 PHASE2
NCT02528201 COMPLETED
Ankylosing Spondylitis
Pfizer
2002-09 PHASE4
NCT00904605 TERMINATED
Osteoarthritis of the Knee
Endo USA Inc., a Keenova Therapeutics Company
2004-06 PHASE4
NCT00476034 COMPLETED
Osteoarthritis
Novartis
2003-12 PHASE3
NCT00904397 TERMINATED
Chronic Low Back Pain
Endo USA Inc., a Keenova Therapeutics Company
2004-07 PHASE4
NCT00336960 COMPLETED
Colorectal Cancer
Vanderbilt-Ingram Cancer Center
2002-07 PHASE2
NCT00137852 COMPLETED
Esophageal Cancer
Dana-Farber Cancer Institute
2002-01 PHASE2
NCT00175032 COMPLETED
Osteoarthritis; Peptic Ulcer
Takeda
2003-07 PHASE3
NCT00608595 TERMINATED
Colorectal Cancer
Vanderbilt-Ingram Cancer Center
2002-07
NCT00030420 COMPLETED
Lung Cancer
Barbara Ann Karmanos Cancer Institute
2001-10 PHASE2
NCT00080782 TERMINATED
Metastatic Cancer; Prostate Cancer
M.D. Anderson Cancer Center
2002-02 PHASE2
NCT00652925 COMPLETED
Arthritis, Juvenile Rheumatoid
Pfizer
2002-10 PHASE3
NCT00366938 COMPLETED
Osteoarthritis, Knee
Novartis
2003-09 PHASE3
NCT00231829 TERMINATED
Uterine Cancer
Mark H. Einstein
2003-04 PHASE2
NCT00367315 COMPLETED
Knee Osteoarthritis
Novartis
2003-09 PHASE3
NCT00092352 COMPLETED
Osteoarthritis
Merck Sharp & Dohme LLC
2003-04-29 PHASE3
NCT00092365 COMPLETED
Osteoarthritis
Merck Sharp & Dohme LLC
2003-04-01 PHASE3
NCT00176813 COMPLETED
Pancreatic Cancer
University of Michigan Rogel Cancer Center
2003-03 PHASE2
NCT00620867 COMPLETED
Osteoarthritis, Knee
Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
2002-10 PHASE4
NCT00020878 COMPLETED
Lung Cancer
Jonsson Comprehensive Cancer Center
2001-03 PHASE2
NCT02099136 COMPLETED
No Evidence of Disease
National Cancer Institute (NCI)
1999-09 PHASE2
NCT00267215 COMPLETED
Osteoarthritis
Novartis
2000-11 PHASE3
NCT00355576 COMPLETED
Amyotrophic Lateral Sclerosis
Columbia University
2006-07 PHASE2
NCT00471341 COMPLETED
Hypertension and Coronary Artery Disease
University of Florida
2002-07 PHASE4
NCT00072540 WITHDRAWN
Stage 0 Cervical Cancer; High-grade Squamous Intraepithelial Lesion
SWOG Cancer Research Network
PHASE2
NCT00365313 COMPLETED
Arthritis; Bleeding Ulcer
Chinese University of Hong Kong
2002-08 PHASE3
NCT00036283 COMPLETED
Precancerous Conditions
Pfizer
2000-11 PHASE2
NCT00630929 COMPLETED
Osteoarthritis, Knee
Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
2003-01 PHASE4
NCT00025051 WITHDRAWN
Non-melanomatous Skin Cancer
National Cancer Institute (NCI)
PHASE2
NCT00328432 COMPLETED
Breast Cancer
University of Kansas
2003-06 PHASE1
NCT00043043 COMPLETED
Colorectal Cancer
National Cancer Institute (NCI)
2003-05 PHASE2
NCT00001693 COMPLETED
Colorectal Neoplasm; Hereditary Nonpolyposis
National Cancer Institute (NCI)
1998-03 PHASE1
NCT00348452 COMPLETED
Chronic Pain
Bausch Health Americas, Inc.
2002-09 PHASE3
NCT00218205 UNKNOWN
Prostate Cancer
Department of Veterans Affairs, New Jersey
2002-07 PHASE2
NCT00141154 COMPLETED
Low Back Pain
Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
2004-10 PHASE3
NCT00565500 COMPLETED
Ischemic Heart Disease; Osteoarthritis
University of Chieti
2003-04 PHASE4
NCT00638807 COMPLETED
Osteoarthritis, Knee
Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
2003-12 PHASE4
NCT00357617 UNKNOWN
Head and Neck Cancer
Centre Hospitalier Universitaire Vaudois
2006-06 PHASE1; PHASE2
NCT00043680 COMPLETED
Macular Degeneration
National Eye Institute (NEI)
2002-08 PHASE2
NCT00163241 TERMINATED
Osteoarthritis
Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
2004-06 PHASE3
NCT00648141 COMPLETED
Spondylitis, Ankylosing
Pfizer
2003-01 PHASE3
NCT00072072 COMPLETED
Lung Cancer
Jonsson Comprehensive Cancer Center
2003-08 PHASE1
NCT00181532 COMPLETED
Non Small Cell Lung Carcinoma
Maastricht Radiation Oncology
2003-05 PHASE2
NCT00640432 COMPLETED
Low Back Pain
Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
2003-10 PHASE4
NCT00150280 COMPLETED
Pain, Postoperative
Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
2004-10 PHASE3
NCT00215345 UNKNOWN
Prostate Cancer
Department of Veterans Affairs, New Jersey
2002-08 PHASE2
NCT00359151 TERMINATED
Osteoarthritis; Pain
Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
2006-11 PHASE4
NCT00640627 COMPLETED
Osteoarthritis, Knee
Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
2003-12 PHASE4
NCT00640809 COMPLETED
Bowel Diseases, Inflammatory
Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
2003-10 PHASE4
NCT00293436 WITHDRAWN
Liver Cancer
University of California, San Francisco
2005-01 PHASE1; PHASE2
NCT00664690 WITHDRAWN
Pain
London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
PHASE4
NCT00065559 TERMINATED
Diabetic Nephropathy
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
2003-04
NCT00137033 COMPLETED
Peptic Ulcers
Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
2004-09 PHASE4
NCT00633438 COMPLETED
Arthroscopy
Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
2004-01 PHASE4
NCT00473980 COMPLETED
Colorectal Cancer
Göteborg University
1998-12 PHASE4
NCT00093678 WITHDRAWN
Cachexia; Lymphoma; Melanoma (Skin); Ovarian Cancer; Pain; Sarcoma; Unspecified Adult Solid Tumor, Protocol Specific
Eastern Cooperative Oncology Group
NCT00032890 COMPLETED
Osteoarthritis
US Department of Veterans Affairs
2000-04 PHASE3
NCT00050479 COMPLETED
Macular Degeneration
National Eye Institute (NEI)
2002-12 PHASE3
NCT01020279 COMPLETED
Musculoskeletal Pain
X-pert Med GmbH
2009-10 PHASE1
NCT00072553 UNKNOWN
Colorectal Cancer
GERCOR - Multidisciplinary Oncology Cooperative Group
2003-09 PHASE2
NCT00639483 COMPLETED
Schizophrenia
Pfizer
2003-03 PHASE2
NCT00174317 COMPLETED
Osteoarthritis, Hip
Pfizer
2003-08 PHASE4
NCT00317733 COMPLETED
Osteoarthritis, Knee
IDEA AG
PHASE2
NCT00023621 COMPLETED
Non-melanomatous Skin Cancer
University of California, San Francisco
2001-02 PHASE2
NCT00533247 UNKNOWN
Postoperative Pain
Zanbilowicz, Adam, DPM MS
NCT00006381 COMPLETED
Breast Cancer
Memorial Sloan Kettering Cancer Center
2000-06 PHASE2
NCT00274898 UNKNOWN
Lung Cancer
GERCOR - Multidisciplinary Oncology Cooperative Group
2004-05 PHASE2
NCT00500279 UNKNOWN
Angioplasty, Transluminal, Percutaneous Coronary; Coronary Restenosis
Seoul National University Hospital
2006-11 PHASE4
NCT00296127 COMPLETED
Healthy Volunteers
Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
2006-02 PHASE1
NCT00211952 SUSPENDED
Non-Small Cell Lung Cancer
Medical University of Gdansk
2004-03 PHASE3
NCT00633386 COMPLETED
Arthroscopy
Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
2003-02 PHASE4
NCT00261586 COMPLETED
Analgesics
Johnson & Johnson Consumer and Personal Products Worldwide
PHASE4
NCT00037180 TERMINATED
Neoplasm Metastasis; Colorectal Neoplasms
Pfizer
2002-04 PHASE2

(data from https://clinicaltrials.gov, updated on 2026-03-05)

Check the Celecoxib (SC-58635) product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Compliance for Clinical Use

Mechanism and Biochemical Profile

Celecoxib selectively binds to cyclooxygenase-2 (COX-2) through its polar sulfonamide side chain inserting into a hydrophilic side pocket near the active catalytic site. By inhibiting COX-2 enzyme activity, the compound blocks downstream prostaglandin production, thereby suppressing inflammatory signaling pathways to relieve pain and inflammation in clinical trial conditions such as knee osteoarthritis and postoperative pain.

Appendix RUO and cGMP Quality Standards

Quality Dimension RUO (Research Use Only) cGMP (Current Good Manufacturing Practice)
Clinical Applicability Prohibited in human clinical trials or medical diagnostics. Mandatory for human clinical trials (Phase I–III) and therapies.
Regulatory Status Non-regulated grade; exempt from drug manufacturing laws. Legally enforced by health authorities (e.g., FDA, EMA, NMPA).
Facility Environment Unclassified analytical or research laboratories. Validated Cleanrooms (ISO Class 5–8) with continuous monitoring.
Quality Control Basic purity and activity testing. Rigorous safety release testing (Sterility, Endotoxin, Mycoplasma).
Process Validation Basic equipment calibration; no process validation required. Full qualification (IQ/OQ/PQ) and complete batch records.
Quality Assurance Vendor self-declared without required formal QMS. Mandatory QA/QC unit, Change Control, CAPA, and vendor audits.
Regulatory Impact High risk of IND rejection if used as a critical raw material. Required for IND/NDA filings, supported by Drug Master Files (DMF).

Footnotes

Regulatory Note: Governed by FDA (21 CFR Parts 210/211/312), EMA (EudraLex Vol 4), ICH Guidelines (E6/Q7/Q9/Q10), and compendial standards (USP <71>/<85>/<1043>).

Note: Technical data last updated: Sep 1, 2026.