Numerous clinical trials spanning Phase 1 through Phase 4 evaluate methotrexate across diverse therapeutic indications. These studies investigate its efficacy in autoimmune and inflammatory conditions, such as rheumatoid arthritis, psoriatic arthritis, and erosive hand osteoarthritis, as well as oncological malignancies, including breast cancer and NK-cell lymphoma. Sponsored by various academic centers and pharmaceutical entities, these trials encompass multiple recruitment statuses—including recruiting, completed, and terminated—reflecting ongoing clinical evaluation of this therapeutic agent.
| NCT Number | Recruitment | Conditions | Sponsor/Collaborators | Start Date | Phases |
|---|---|---|---|---|---|
| NCT05725200 | RECRUITING | Metastatic Colorectal Cancer |
Oslo University Hospital |
2022-09-27 | PHASE2 |
| NCT07072585 | NOT_YET_RECRUITING | Stage II T Lymphoblastic Leukemia/Lymphoma; Stage III T Lymphoblastic Leukemia/Lymphoma; Stage IV T Lymphoblastic Leukemia/Lymphoma; T Acute Lymphoblastic Leukemia; T Lymphoblastic Lymphoma |
Children's Oncology Group |
2026-08-28 | PHASE2; PHASE3 |
| NCT07387926 | RECRUITING | Acute Lymphoblastic Leukemia; Leukemia, Lymphoblastic, Acute, Philadelphia-Positive; Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia |
Novartis Pharmaceuticals |
2026-07-05 | PHASE1; PHASE2 |
| NCT07321912 | RECRUITING | Osteosarcoma; Ewing Sarcoma |
Milton S. Hershey Medical Center |
2026-06-05 | PHASE2 |
| NCT06128070 | RECRUITING | Acute Lymphoblastic Leukemia; Acute Myeloid Leukemia; Myelodysplastic Syndrome |
City of Hope Medical Center |
2024-07-16 | PHASE2 |
| NCT07228624 | RECRUITING | Myelodysplastic/Myeloproliferative Neoplasm; Primary Myelofibrosis; Secondary Myelofibrosis |
Fred Hutchinson Cancer Center |
2026-02-04 | PHASE2 |
| NCT07227584 | RECRUITING | Acute Lymphoblastic Leukemia; Philadelphia Chromosome-Negative Lymphoblastic Leukemia; Acute Lymphoblastic Leukemia (ALL); Leukemia |
Dana-Farber Cancer Institute |
2026-04-03 | PHASE2 |
| NCT07643038 | NOT_YET_RECRUITING | Rheumatoid Arthritis Associated Interstitial Lung Disease |
Chinese SLE Treatment And Research Group |
2026-09-20 | PHASE4 |
| NCT04293562 | RECRUITING | Acute Myeloid Leukemia |
Children's Oncology Group |
2020-07-21 | PHASE3 |
| NCT06918431 | RECRUITING | B Acute Lymphoblastic Leukemia, Philadelphia Chromosome Negative; Lymphoblastic Lymphoma |
City of Hope Medical Center |
2025-10-10 | PHASE2 |
| NCT02714634 | RECRUITING | Rheumatoid Arthritis; Insufficient Response to Methotrexate or Leflunomide |
University Hospital, Strasbourg, France |
2016-03-30 | PHASE4 |
| NCT04960579 | ACTIVE_NOT_RECRUITING | Multiple Myeloma |
Poseida Therapeutics, Inc. |
2022-05-05 | PHASE1 |
| NCT07410520 | RECRUITING | Primary Central Nervous System Lymphoma (PCNSL); Secondary Central Nervous System Lymphoma (SCNSL) |
The First Affiliated Hospital with Nanjing Medical University |
2026-02-07 | PHASE2 |
| NCT07560826 | NOT_YET_RECRUITING | Osteosarcoma in Children; Osteosarcoma in Adolescents and Young Adults |
Wake Forest University Health Sciences |
2026-08 | PHASE2 |
| NCT07498465 | WITHDRAWN | Acute Lymphoblastic Leukemia; Acute Myeloid Leukemia; Childhood Acute Lymphoblastic Leukemia; Childhood Acute Myeloid Leukemia; Childhood Mixed Phenotype Acute Leukemia; Mixed Phenotype Acute Leukemia |
Children's Oncology Group |
2026-09-10 | PHASE1 |
| NCT07185373 | RECRUITING | Primary Central Nervous System Lymphoma |
Huashan Hospital |
2025-10-01 | PHASE2; PHASE3 |
| NCT06204614 | ENROLLING_BY_INVITATION | Muscle Invasive Bladder Urothelial Carcinoma |
Brigham and Women's Hospital |
2024-06-14 | EARLY_PHASE1 |
| NCT04546399 | RECRUITING | Down Syndrome; Recurrent B Acute Lymphoblastic Leukemia |
National Cancer Institute (NCI) |
2020-12-17 | PHASE2 |
| NCT07388498 | RECRUITING | Uncontrolled Gout |
Amgen |
2026-02-09 | PHASE3 |
| NCT06262438 | RECRUITING | Acute Myeloid Leukemia in Children |
Princess Maxima Center for Pediatric Oncology |
2024-02-06 | PHASE2 |
| NCT04931368 | ACTIVE_NOT_RECRUITING | Primary Central Nervous System Lymphoma |
Klinikum Stuttgart |
2021-06-28 | PHASE3 |
| NCT07643103 | NOT_YET_RECRUITING | Ph- Acute Lymphoblastic Leukemia (Ph-ALL) |
Institute of Hematology & Blood Diseases Hospital, China |
2026-06-12 | PHASE2 |
| NCT06646211 | NOT_YET_RECRUITING | Primary Central Nervous System Lymphoma (PCNSL); Non Hodgkin Lymphoma (NHL) |
Sun Yat-sen University |
2025-01-01 | PHASE2 |
| NCT07486843 | RECRUITING | Psoriatic Arthritis (PsA) |
Chinese University of Hong Kong |
2026-03-16 | PHASE4 |
| NCT03719105 | RECRUITING | NK-Cell Lymphoma; NK-Cell Leukemia; Peripheral T Cell Lymphoma |
New York Medical College |
2019-03-01 | EARLY_PHASE1 |
| NCT05503875 | RECRUITING | Immunoclassification; Psoriasis |
Second Affiliated Hospital, Zhejiang University, School of Medicine |
2023-01-01 | |
| NCT07242092 | RECRUITING | Autoimmune Rheumatic Diseases |
University of Sao Paulo General Hospital |
2026-06-22 | PHASE4 |
| NCT04872790 | ACTIVE_NOT_RECRUITING | B Acute Lymphoblastic Leukemia; B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1; Mixed Phenotype Acute Leukemia; Recurrent B Acute Lymphoblastic Leukemia; Recurrent Mixed Phenotype Acute Leukemia |
OHSU Knight Cancer Institute |
2022-09-02 | PHASE1 |
| NCT07280156 | RECRUITING | Gout |
Protalix |
2025-12-22 | PHASE2 |
| NCT03914625 | ACTIVE_NOT_RECRUITING | B Acute Lymphoblastic Leukemia; B Lymphoblastic Lymphoma; Down Syndrome |
National Cancer Institute (NCI) |
2019-07-03 | PHASE3 |
| NCT07624903 | NOT_YET_RECRUITING | Ectopic Pregnancy |
Kafrelsheikh University |
2026-06 | PHASE2 |
| NCT07406230 | NOT_YET_RECRUITING | Primary Central Nervous System Lymphoma |
Assistance Publique Hopitaux De Marseille |
2026-04 | |
| NCT03710772 | ACTIVE_NOT_RECRUITING | Mantle Cell Lymphoma |
M.D. Anderson Cancer Center |
2019-05-01 | PHASE2 |
| NCT03892785 | ACTIVE_NOT_RECRUITING | Giant Cell Arteritis |
Centre Hospitalier Universitaire Dijon |
2020-01-27 | PHASE3 |
| NCT02981628 | ACTIVE_NOT_RECRUITING | Recurrent B Acute Lymphoblastic Leukemia; Recurrent B Lymphoblastic Lymphoma; Refractory B Acute Lymphoblastic Leukemia; Refractory B Lymphoblastic Lymphoma |
Children's Oncology Group |
2017-06-19 | PHASE2 |
| NCT05353829 | ACTIVE_NOT_RECRUITING | Rheumatoid Arthritis |
Region Västerbotten |
2022-04-28 | PHASE4 |
| NCT06475235 | RECRUITING | Lymphoma; Primary Central Nervous System Lymphoma |
Dana-Farber Cancer Institute |
2024-10-18 | PHASE1 |
| NCT07581418 | NOT_YET_RECRUITING | Chronic Plaque Psoriasis |
Pak Emirates Military Hospital |
2026-06-01 | |
| NCT04579848 | ACTIVE_NOT_RECRUITING | Hand Osteoarthritis; Erosive Osteoarthritis |
Diakonhjemmet Hospital |
2021-08-12 | PHASE4 |
| NCT07446400 | RECRUITING | Healthy Volunteers |
Otsuka Pharmaceutical Development & Commercialization, Inc. |
2026-03-31 | PHASE1 |
| NCT02877303 | RECRUITING | B Acute Lymphoblastic Leukemia; B Lymphoblastic Lymphoma |
M.D. Anderson Cancer Center |
2016-11-01 | PHASE2 |
| NCT05519579 | RECRUITING | Acute Lymphoblastic Leukemia |
Northside Hospital, Inc. |
2023-06-30 | PHASE2 |
| NCT00501826 | RECRUITING | T Acute Lymphoblastic Leukemia; T Lymphoblastic Lymphoma |
M.D. Anderson Cancer Center |
2007-07-11 | PHASE2 |
| NCT07008846 | ACTIVE_NOT_RECRUITING | Moderate to Severe Rheumatoid Arthritis |
Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh |
2025-05-10 | PHASE3 |
| NCT06210750 | WITHDRAWN | T Acute Lymphoblastic Leukemia; T Lymphoblastic Lymphoma |
National Cancer Institute (NCI) |
2024-08-09 | PHASE2 |
| NCT07176390 | ACTIVE_NOT_RECRUITING | Arthritis, Rheumatoid |
Merck Sharp & Dohme LLC |
2025-10-08 | PHASE2 |
| NCT02203526 | ACTIVE_NOT_RECRUITING | Primary Central Nervous System Lymphoma |
National Cancer Institute (NCI) |
2014-08-14 | PHASE1 |
| NCT02422641 | RECRUITING | Metastatic Breast Cancer; Leptomeningeal Disease |
Wake Forest University Health Sciences |
2015-05 | PHASE2 |
| NCT06554561 | RECRUITING | PCNSL |
Second Affiliated Hospital, Zhejiang University, School of Medicine |
2024-08-31 | PHASE1; PHASE2 |
| NCT06554626 | RECRUITING | Precursor B-Cell Lymphoblastic Leukemia |
First Affiliated Hospital of Zhejiang University |
2024-08-15 | PHASE2 |
| NCT07361133 | NOT_YET_RECRUITING | Squamous Cell Carcinoma; Advanced Head and Neck Cancer |
National Cancer Institute, Egypt |
2026-04 | PHASE2 |
| NCT07543640 | NOT_YET_RECRUITING | Flexural Psoriasis (Also Known as Inverse or Intertriginous Psoriasis) and Genital Psoriasis |
Eman Raafat Said |
2026-04-01 | PHASE2 |
| NCT02205762 | ACTIVE_NOT_RECRUITING | Langerhans Cell Histiocytosis |
North American Consortium for Histiocytosis |
2016-11-02 | PHASE2; PHASE3 |
| NCT06530576 | RECRUITING | T-LGL Leukemia; NK-LGL Leukemia |
Institute of Hematology & Blood Diseases Hospital, China |
2024-08-10 | PHASE2 |
| NCT06578728 | TERMINATED | Nail Psoriasis |
Weill Medical College of Cornell University |
2025-09-10 | PHASE4 |
| NCT06768294 | NOT_YET_RECRUITING | Calcium Pyrophosphate Deposition Disease; Chondrocalcinosis |
I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio |
2025-01 | PHASE2 |
| NCT04384692 | ACTIVE_NOT_RECRUITING | Primary Myelofibrosis; Secondary Myelofibrosis |
Fred Hutchinson Cancer Center |
2020-12-18 | PHASE2 |
| NCT02723994 | COMPLETED | Leukemia |
Incyte Corporation |
2016-09-30 | PHASE2 |
| NCT03960177 | COMPLETED | Osteosarcoma |
OHSU Knight Cancer Institute |
2019-03-27 | EARLY_PHASE1 |
| NCT06671054 | RECRUITING | Rheumatoid Arthritis (RA) |
SynAct Pharma Aps |
2024-10-01 | PHASE2 |
| NCT02710734 | COMPLETED | Urothelial Carcinoma of the Bladder |
Fox Chase Cancer Center |
2016-02-24 | PHASE2 |
| NCT05054426 | UNKNOWN | Diffuse Large B Cell Lymphoma; Central Nervous System Lymphoma |
Peking Union Medical College Hospital |
2021-10-08 | PHASE3 |
| NCT03775460 | ACTIVE_NOT_RECRUITING | Erythema Nodosum Leprosum |
London School of Hygiene and Tropical Medicine |
2023-01-15 | |
| NCT02416388 | RECRUITING | Acute Myeloid Leukemia (AML) |
University Hospital, Angers |
2015-01 | PHASE2; PHASE3 |
| NCT06231745 | COMPLETED | Rheumatoid Arthritis |
Mostafa Bahaa |
2024-01-31 | PHASE3 |
| NCT04737889 | RECRUITING | Primary Central Nervous System Lymphoma |
Henan Cancer Hospital |
2021-01-13 | PHASE2 |
| NCT06073093 | COMPLETED | Rheumatoid Arthritis |
Sanofi |
2023-11-07 | PHASE2 |
| NCT06936215 | RECRUITING | Diffuse Cutaneous Systemic Sclerosis |
Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh |
2024-01-01 | PHASE3 |
| NCT03728478 | RECRUITING | Oligoarthritis, Juvenile; Polyarthritis, Juvenile, Rheumatoid Factor Negative |
Istituto Giannina Gaslini |
2019-05-29 | PHASE3 |
| NCT06289205 | UNKNOWN | Proliferative Vitreoretinopathy |
University of Health Sciences Lahore |
2024-03 | PHASE1; PHASE2 |
| NCT04196868 | COMPLETED | Arthritis, Rheumatoid |
University Hospital, Bordeaux |
2020-12-03 | PHASE2 |
| NCT04841434 | COMPLETED | CNS Lymphoma |
Charite University, Berlin, Germany |
2021-06-01 | PHASE1; PHASE2 |
| NCT04668768 | SUSPENDED | Lymphoma |
Fox Chase Cancer Center |
2021-04-16 | PHASE2 |
| NCT03371667 | UNKNOWN | Allogeneic Disease; GVH - Graft Versus Host Reaction; GVHD, Acute; Stem Cell Transplant Complications |
Assistance Publique - Hôpitaux de Paris |
2018-08-16 | PHASE3 |
| NCT06186219 | COMPLETED | Tophaceous Gout |
University of California, Los Angeles |
2024-04-10 | PHASE1 |
| NCT06951282 | COMPLETED | Methotrexate Spermatotoxicity |
Ain Shams University |
2024-05-02 | PHASE1; PHASE2 |
| NCT06175338 | ACTIVE_NOT_RECRUITING | Rheumatoid Arthritis |
Mabscale, LLC |
2023-06-14 | PHASE1 |
| NCT06108453 | UNKNOWN | Drug Interactions |
Seoul National University Bundang Hospital |
2023-08-21 | PHASE1 |
| NCT04610476 | UNKNOWN | Psoriatic Arthritis; Withdrawal; Reduction |
University of Erlangen-Nürnberg Medical School |
2020-10-19 | PHASE3 |
| NCT04798755 | UNKNOWN | Uveitis |
Hospital San Carlos, Madrid |
2022-01-12 | PHASE3 |
| NCT04314193 | UNKNOWN | Sarcoidosis, Pulmonary |
Erasmus Medical Center |
2020-06-01 | PHASE4 |
| NCT00878254 | COMPLETED | Mantle-Cell Lymphoma |
University of Miami |
2009-03-25 | PHASE2 |
| NCT04383743 | COMPLETED | Stage II Bladder Cancer AJCC v8; Stage IIIA Bladder Cancer AJCC v8; Muscle Invasive Bladder Carcinoma |
University of Washington |
2020-11-24 | PHASE2 |
| NCT06324604 | Not yet recruiting | Healthy Volunteers|Celiac Disease|Type 1 Diabetes |
Mozart Therapeutics Australia Pty Ltd |
2024-06 | Phase 1 |
| NCT05374785 | COMPLETED | Rheumatoid Arthritis |
Celon Pharma SA |
2022-05-01 | PHASE2 |
| NCT06401213 | Recruiting | Healthy |
Mediar Therapeutics|ICON plc |
2024-04-15 | Phase 1 |
| NCT05827497 | UNKNOWN | Rheumatoid Arthritis |
Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh |
2023-04-01 | PHASE4 |
| NCT06281184 | Not yet recruiting | Hand Osteoarthritis|Erosive Osteoarthritis |
Diakonhjemmet Hospital |
2024-03-15 | -- |
| NCT06300333 | Not yet recruiting | Ectopic Pregnancy |
Assiut University |
2024-03 | -- |
| NCT00390793 | COMPLETED | Acute Lymphoblastic Leukemia; BCR-ABL1 Fusion Protein Expression; Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive; Philadelphia Chromosome Positive; Recurrent Acute Lymphoblastic Leukemia; t(9;22) |
M.D. Anderson Cancer Center |
2006-09-28 | PHASE2 |
| NCT06277635 | Recruiting | Rheumatoid Arthritis|Psoriatic Arthritis|Psoriasis |
Phramongkutklao College of Medicine and Hospital |
2024-02-01 | Not Applicable |
| NCT05889338 | UNKNOWN | Psoriasi |
Sohag University |
2023-06 | |
| NCT04129710 | UNKNOWN | Recurrent/RefractoryPrimary Central Nervous System Lymphoma (PCNSL) |
Second Affiliated Hospital, Zhejiang University, School of Medicine |
2020-01-01 | PHASE2 |
| NCT05522582 | ACTIVE_NOT_RECRUITING | Solid Tumors |
Yancheng First People's Hospital |
2021-11-15 | PHASE2 |
| NCT04214626 | COMPLETED | Diffuse Large B Cell Lymphoma |
Henan Cancer Hospital |
2020-01-05 | PHASE2 |
| NCT04481815 | UNKNOWN | PCNSL |
Second Affiliated Hospital, Zhejiang University, School of Medicine |
2020-10-01 | PHASE2 |
| NCT05460832 | COMPLETED | Rheumatoid Arthritis |
Modern Biosciences Ltd |
2022-08-29 | PHASE2 |
| NCT05393050 | UNKNOWN | Rheumatoid Arthritis |
Quan Jiang |
2022-07 | PHASE4 |
| NCT05263505 | TERMINATED | Mucous Membrane Pemphigoid; Cicatrizing Conjunctivitis |
Washington University School of Medicine |
2022-02-21 | PHASE2 |
| NCT05604885 | COMPLETED | Rheumatoid Arthritis |
SynAct Pharma Aps |
2022-11-30 | PHASE2 |
| NCT04895423 | UNKNOWN | Atopic Dermatitis |
National Medical Research Center for Children's Health, Russian Federation |
2021-11-25 | PHASE4 |
| NCT05489224 | COMPLETED | Rheumatoid Arthritis |
Celltrion |
2022-09-14 | PHASE3 |
| NCT04942860 | COMPLETED | Non-segmental Vitiligo |
Nicolaus Copernicus University |
2019-10-01 | PHASE3 |
| NCT04762498 | COMPLETED | Uncontrolled Gout; Chronic Gout |
Amgen |
2021-01-26 | PHASE4 |
| NCT02766465 | COMPLETED | Sickle Cell Disease |
Medical College of Wisconsin |
2017-03-16 | PHASE2 |
| NCT04830878 | WITHDRAWN | Proliferative Vitreoretinopathy |
Stanford University |
2021-04 | PHASE1 |
| NCT02339350 | UNKNOWN | Acute Lymphoblastic Leukemia; Child |
The Korean Society of Pediatric Hematology Oncology |
2015-01 | PHASE2 |
| NCT02313389 | UNKNOWN | Primary Central Nervous System Lymphoma |
Assistance Publique - Hôpitaux de Paris |
2015-09 | PHASE3 |
| NCT05008887 | UNKNOWN | Vitiligo |
Assiut University |
2022-09 | PHASE4 |
| NCT00596154 | COMPLETED | CNS Lymphoma; CNS Brain Cancer; Non-Hodgkin's Lymphoma |
Memorial Sloan Kettering Cancer Center |
2004-12 | PHASE2 |
| NCT05485571 | UNKNOWN | Alopecia Areata |
Sohag University |
2022-08-01 | |
| NCT04958538 | UNKNOWN | Acute Graft Versus Host Disease |
Peking University People's Hospital |
2021-04-21 | PHASE2 |
| NCT04299971 | UNKNOWN | Takayasu Arteritis; Methotrexate; Inhibition; Treatment |
Shanghai Zhongshan Hospital |
2020-03-01 | PHASE4 |
| NCT05363917 | UNKNOWN | Rheumatoid Arthritis |
XBiotech, Inc. |
2022-06-15 | PHASE2 |
| NCT04136262 | UNKNOWN | Rheumatoid Arthritis |
Guang'anmen Hospital of China Academy of Chinese Medical Sciences |
2019-11-25 | PHASE2; PHASE3 |
| NCT05467839 | COMPLETED | Vitiligo |
Sohag University |
2022-07-31 | |
| NCT03589326 | ACTIVE_NOT_RECRUITING | Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia (Ph+ALL) |
Takeda |
2018-10-04 | PHASE3 |
| NCT03155347 | COMPLETED | Rheumatoid Arthritis |
Hoffmann-La Roche |
2017-08-02 | PHASE3 |
| NCT04120350 | UNKNOWN | Primary Central Nervous System Lymphoma |
Peking Union Medical College Hospital |
2019-08-16 | PHASE1; PHASE2 |
| NCT04960644 | COMPLETED | Acute GVH Disease |
Peking University People's Hospital |
2021-06-25 | PHASE3 |
| NCT02772965 | COMPLETED | Pediatric Crohn's Disease |
University of North Carolina, Chapel Hill |
2016-10 | PHASE3 |
| NCT02905110 | COMPLETED | Brain Tumor Recurrent |
The University of Texas Health Science Center, Houston |
2017-10-12 | EARLY_PHASE1 |
| NCT04413617 | COMPLETED | Rheumatoid Arthritis |
Pfizer |
2020-07-29 | PHASE2 |
| NCT04469829 | UNKNOWN | Psoriasis; Metabolic Syndrome |
Universita di Verona |
2020-08-01 | PHASE4 |
| NCT03692416 | UNKNOWN | Vasculitis |
Assiut University |
2018-11-11 | PHASE3 |
| NCT02611037 | COMPLETED | Malignant Pleural Mesothelioma; Mesothelioma |
H. Lee Moffitt Cancer Center and Research Institute |
2016-03-04 | PHASE2 |
| NCT03813147 | COMPLETED | Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome; Recurrent Acute Myeloid Leukemia; Recurrent Myelodysplastic Syndrome; Refractory Acute Myeloid Leukemia; Refractory Myelodysplastic Syndrome |
National Cancer Institute (NCI) |
2019-05-17 | PHASE1 |
| NCT06048224 | COMPLETED | Moderate to Severe Active Rheumatoid Arthritis |
Zhejiang Hisun Pharmaceutical Co. Ltd. |
2020-12-28 | PHASE3 |
| NCT01665677 | COMPLETED | Graft vs Host Disease |
Mehdi Hamadani |
2014-01-20 | PHASE2 |
| NCT04482543 | UNKNOWN | Proliferative Vitreoretinopathy |
Shahid Beheshti University of Medical Sciences |
2020-08-01 | PHASE2; PHASE3 |
| NCT04230213 | COMPLETED | Rheumatoid Arthritis |
Pfizer |
2020-01-13 | PHASE3 |
| NCT03564704 | UNKNOWN | Leukemia; Leukemia, Acute; Adult Lymphoblastic Lymphoma; Leukemia, Lymphoblastic; Leukemia, T Cell; Adult Acute Lymphoblastic Leukemia; Lymphoblastic Lymphoma; Lymphoblastic Leukemia |
Nanfang Hospital, Southern Medical University |
2016-02-14 | PHASE2; PHASE3 |
| NCT03760003 | COMPLETED | Ulcerative Colitis |
Abivax S.A. |
2019-08-13 | PHASE2 |
| NCT04577781 | COMPLETED | Rheumatoid Arthritis |
Lakefront Biotherapeutics NV |
2020-10-12 | PHASE2 |
| NCT03994731 | COMPLETED | Gout |
Amgen |
2019-06-13 | PHASE4 |
| NCT04610567 | UNKNOWN | Coronavirus; Inflammation; Covid19 |
University of Sao Paulo General Hospital |
2020-10-27 | PHASE1; PHASE2 |
| NCT03830203 | COMPLETED | Rheumatoid Arthritis |
Bio-Thera Solutions |
2018-12-19 | PHASE3 |
| NCT03516903 | TERMINATED | Myocardial Infarction, Anterior Wall; Myocardial Remodeling, Ventricular |
University of Sao Paulo |
2018-04-17 | PHASE2; PHASE3 |
| NCT02647762 | TERMINATED | Rheumatoid Arthritis |
Can-Fite BioPharma |
2017-10-30 | PHASE3 |
| NCT04379219 | UNKNOWN | Cesarean Scar Pregnancy |
Mansoura University |
2019-12-01 | PHASE4 |
| NCT02663622 | COMPLETED | Graft Versus Host Disease; Hematopoietic Stem Cell Transplantation; Leukemia |
Oncoimmune, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA) |
2016-09-19 | PHASE2 |
| NCT03445871 | COMPLETED | Rheumatoid Arthritis |
Centre Hospitalier Universitaire de Saint Etienne |
2018-07-02 | PHASE4 |
| NCT03112603 | COMPLETED | Graft-versus-host Disease (GVHD) |
Incyte Corporation |
2017-06-29 | PHASE3 |
| NCT01363128 | COMPLETED | Acute Lymphoblastic Leukemia; Adult Acute Lymphoblastic Leukemia in Complete Remission; Burkitt Leukemia; Burkitt Lymphoma; CD20 Positive; Childhood Acute Lymphoblastic Leukemia in Complete Remission; Lymphoblastic Lymphoma |
M.D. Anderson Cancer Center |
2011-07-12 | PHASE2 |
| NCT01927484 | TERMINATED | Reduction in Pain; Reduction of Inflammation; Improvement in Function |
University of Alexandria |
2020-03-07 | |
| NCT03066466 | WITHDRAWN | Acute Myeloid Leukemia; Acute Lymphocytic Leukemia; Myelodysplastic Syndrome |
Loyola University |
2019-12-10 | PHASE3 |
| NCT02487069 | COMPLETED | Acute Leukemia; Chronic Myeloid Leukemia; Myelodysplastic Syndrome |
Nanfang Hospital, Southern Medical University |
2015-06 | |
| NCT02677181 | COMPLETED | aGVHD |
Chinese PLA General Hospital |
2016-01 | PHASE4 |
| NCT03275025 | COMPLETED | Rheumatoid Arthritis |
Yungjin Pharm. Co., Ltd. |
2017-04-01 | PHASE2 |
| NCT03490396 | TERMINATED | Oral Mucositis |
Midatech Pharma US Inc. |
2018-05-15 | PHASE4 |
| NCT04046250 | COMPLETED | Mucositis |
Tosk, Inc. |
2019-05-15 | PHASE2 |
| NCT02378298 | COMPLETED | Ophthalmopathy, Thyroid-Associated |
Göteborg University |
2011-12 | PHASE4 |
| NCT02152696 | COMPLETED | Persistent Pregnancy of Unknown Location; Ectopic Pregnancy |
Yale University |
2014-07-25 | PHASE3 |
| NCT02393859 | COMPLETED | Leukemia, Acute Lymphoblastic |
Amgen |
2015-11-10 | PHASE3 |
| NCT03280979 | UNKNOWN | Gestational Trophoblastic Disease |
Assiut University |
2017-10 | PHASE2; PHASE3 |
| NCT02916979 | COMPLETED | Leukemia, Lymphoid; Leukemia, Myeloid; Myelodysplastic Syndromes; Myelofibrosis; Lymphoma, Malignant; Multiple Myeloma; Waldenstrom Macroglobulinemia |
Dartmouth-Hitchcock Medical Center |
2016-09-06 | PHASE1 |
| NCT03107299 | COMPLETED | Methotrexate; Polyarthritis; Rheumatoid |
Centre Hospitalier Universitaire, Amiens |
2016-07-05 | |
| NCT00857389 | COMPLETED | Stem Cell Transplantation; Leukemia; Lymphoma |
M.D. Anderson Cancer Center |
2009-03-02 | PHASE2 |
| NCT03063983 | UNKNOWN | Osteosarcoma |
Grupo de Apoio ao Adolescente e a Crianca com Cancer |
2017-01-02 | PHASE2 |
| NCT04177173 | COMPLETED | Arthritis, Rheumatoid |
King Edward Medical University |
2017-09-01 | PHASE4 |
| NCT03173040 | UNKNOWN | Niu Bang Zi Pill; Rheumatoid Arthritis |
Cui xuejun |
2018-07 | PHASE2; PHASE3 |
| NCT02831855 | COMPLETED | Rheumatoid Arthritis |
Pfizer |
2016-09-01 | PHASE4 |
| NCT03139136 | COMPLETED | Rheumatoid Arthritis |
Modern Biosciences Ltd |
2017-05-30 | PHASE2 |
| NCT03001219 | TERMINATED | Rheumatoid Arthritis |
Hoffmann-La Roche |
2016-12-22 | PHASE2 |
| NCT00707083 | COMPLETED | Leukemia |
Prince of Wales Hospital, Shatin, Hong Kong |
2008-05-01 | PHASE3 |
| NCT02412670 | COMPLETED | High Grade Upper Tract Urothelial Carcinoma |
ECOG-ACRIN Cancer Research Group |
2015-08-27 | PHASE2 |
| NCT02889796 | COMPLETED | Rheumatoid Arthritis |
Gilead Sciences |
2016-08-30 | PHASE3 |
| NCT01535053 | COMPLETED | Choriocarcinoma; FIGO Stage I Gestational Trophoblastic Tumor; FIGO Stage II Gestational Trophoblastic Tumor; FIGO Stage III Gestational Trophoblastic Tumor; Hydatidiform Mole |
GOG Foundation |
2012-06-18 | PHASE3 |
| NCT02706873 | COMPLETED | Rheumatoid Arthritis |
AbbVie |
2016-02-23 | PHASE3 |
| NCT01737671 | COMPLETED | Brain Tumor; Malignant Neoplasm of Fourth Ventricle of Brain |
M.D. Anderson Cancer Center |
2012-12-27 | EARLY_PHASE1 |
| NCT02969044 | COMPLETED | Rheumatoid Arthritis |
Pfizer |
2016-12-20 | PHASE2 |
| NCT01156883 | COMPLETED | Leukemia |
Gruppo Italiano Malattie EMatologiche dell'Adulto |
2010-04 | |
| NCT03239600 | WITHDRAWN | Autoimmune Diseases |
GlaxoSmithKline |
2017-09-19 | PHASE2 |
| NCT03058471 | COMPLETED | Early Chikungunya Arthritis |
Post Graduate Institute of Medical Education and Research, Chandigarh |
2016-12 | |
| NCT02208037 | COMPLETED | Acute Leukemia; Chronic Myelogenous Leukemia; Myelodysplasia; Chronic Lymphocytic Leukemia; Small Lymphocytic Lymphoma; Lymphoma, B-Cell; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Hodgkin's Lymphoma |
National Heart, Lung, and Blood Institute (NHLBI) |
2014-08 | PHASE2 |
| NCT02451748 | COMPLETED | Rheumatoid Arthritis |
University of Illinois at Chicago |
2015-08 | PHASE4 |
| NCT02389400 | COMPLETED | Langerhans Cell Histiocytosis |
Peking Union Medical College Hospital |
2014-01 | PHASE2 |
| NCT02553018 | COMPLETED | Arthritis, Rheumatoid |
Nordic Pharma SAS |
2015-09 | PHASE3 |
| NCT02433184 | COMPLETED | Rheumatoid Arthritis |
University of Leeds |
2011-07 | PHASE4 |
| NCT02683564 | UNKNOWN | Rheumatoid Arthritis |
Epirus Biopharmaceuticals (Switzerland) GmbH |
2016-02 | PHASE3 |
| NCT01481272 | COMPLETED | Diffuse Large B Cell Lymphoma |
Polish Lymphoma Research Group |
2011-11 | PHASE2 |
| NCT02305849 | COMPLETED | Rheumatoid Arthritis |
Astellas Pharma Inc |
2014-07-25 | PHASE3 |
| NCT00551460 | COMPLETED | Leukemia |
SWOG Cancer Research Network |
2007-11-15 | PHASE2 |
| NCT02252042 | COMPLETED | Head and Neck Squamous Cell Cancer |
Merck Sharp & Dohme LLC |
2014-11-17 | PHASE3 |
| NCT01393405 | COMPLETED | Ulcerative Colitis |
University of North Carolina, Chapel Hill |
2012-02 | PHASE2 |
| NCT01875237 | TERMINATED | Leukemia; Myeloma; Myeloproliferative Diseases |
M.D. Anderson Cancer Center |
2013-12-27 | PHASE1; PHASE2 |
| NCT02480946 | COMPLETED | Arthritis, Rheumatoid |
Modern Biosciences Ltd |
2015-07 | PHASE1 |
| NCT02644499 | COMPLETED | Rheumatoid Arthritis |
Jawaharlal Institute of Postgraduate Medical Education & Research |
2015-12-31 | PHASE4 |
| NCT02744196 | COMPLETED | Rheumatoid Arthritis |
Biocad |
2015-01 | PHASE3 |
| NCT02504268 | COMPLETED | Rheumatoid Arthritis |
Bristol-Myers Squibb |
2015-09-03 | PHASE3 |
| NCT02467504 | COMPLETED | Rheumatoid Arthritis |
Peking University People's Hospital |
2015-07-01 | PHASE2 |
| NCT01987102 | COMPLETED | Osteosarcoma |
Isofol Medical AB |
2013-12 | PHASE1; PHASE2 |
| NCT02319642 | COMPLETED | Rheumatoid Arthritis |
UCB Pharma SA |
2014-11 | PHASE3 |
| NCT02478424 | UNKNOWN | Graft vs Host Disease |
Rabin Medical Center |
2015-07 | PHASE2 |
| NCT00068250 | COMPLETED | Brain and Central Nervous System Tumors; Lymphoma |
Radiation Therapy Oncology Group |
2003-07 | PHASE1; PHASE2 |
| NCT01758666 | UNKNOWN | Osteosarcoma |
Tianjin Medical University Cancer Institute and Hospital |
2012-09 | |
| NCT02270788 | COMPLETED | Acute Myeloid Leukemia |
St. Jude Children's Research Hospital |
2015-04-02 | PHASE1 |
| NCT02940561 | UNKNOWN | Psoriasis; Rheumatoid Arthritis |
Amneal Pharmaceuticals, LLC |
2016-08 | PHASE1 |
| NCT02046616 | COMPLETED | Rheumatoid Arthritis |
Hoffmann-La Roche |
2014-05-28 | PHASE3 |
| NCT01948388 | COMPLETED | Rheumatoid Arthritis |
Gaylis, Norman B., M.D. |
2013-09 | PHASE4 |
| NCT02867306 | COMPLETED | Rheumatoid Arthritis |
Astellas Pharma Global Development, Inc. |
2016-07-25 | PHASE1 |
| NCT01446978 | UNKNOWN | Vaccine Response Impaired |
Sormland County Council, Sweden |
2011-09 | PHASE2 |
| NCT01749111 | TERMINATED | Acute Myelogenous Leukemia; Acute Lymphoid Leukemia; Myeloproliferative Disease; Myelodysplastic Syndrome; Chronic Myeloid Leukemia; Chronic Myelomonocytic Leukemia |
Hospital Israelita Albert Einstein |
2012-12 | PHASE3 |
| NCT02748785 | COMPLETED | Arthritis, Rheumatoid |
Seoul National University Hospital |
2015-09 | PHASE4 |
| NCT02309359 | COMPLETED | Rheumatoid Arthritis |
Ablynx, a Sanofi company |
2015-01 | PHASE2 |
| NCT01941095 | COMPLETED | Rheumatoid Arthritis |
Hoffmann-La Roche |
2013-11-20 | PHASE3 |
| NCT02349451 | COMPLETED | Psoriatic Arthritis |
AbbVie |
2015-04-28 | PHASE2 |
| NCT02393378 | TERMINATED | Rheumatoid Arthritis |
Takeda |
2015-04-08 | PHASE2 |
| NCT07094880 | COMPLETED | Methotrexate Adverse Reaction; Advantage of Using Subcutaneous Route for Methotrexate |
Bangladesh Medical University |
2015-06-01 | PHASE4 |
| NCT01987479 | COMPLETED | Rheumatoid Arthritis |
Hoffmann-La Roche |
2014-01-30 | PHASE3 |
| NCT02379091 | COMPLETED | Rheumatoid Arthritis |
Takeda |
2014-12-17 | PHASE2 |
| NCT01791153 | COMPLETED | Giant Cell Arteritis |
Hoffmann-La Roche |
2013-07-22 | PHASE3 |
| NCT00381680 | COMPLETED | B-cell Childhood Acute Lymphoblastic Leukemia; L1 Childhood Acute Lymphoblastic Leukemia; L2 Childhood Acute Lymphoblastic Leukemia; Intermediate Risk Recurrent Childhood Acute Lymphoblastic Leukemia |
Children's Oncology Group |
2007-03 | PHASE3 |
| NCT01766375 | UNKNOWN | Acute Myeloid Leukemia |
Guangxi Medical University |
2012-08 | PHASE3 |
| NCT01823315 | UNKNOWN | Gestational Trophoblastic Disease; Gestational Trophoblastic Neoplasia; Gestational Trophoblastic Tumor; Gestational Trophoblastic Neoplasms |
Ding Ma |
2012-12 | PHASE3 |
| NCT01802593 | TERMINATED | Crohn's Disease |
Prof. Arie Levine |
2013-02 | PHASE4 |
| NCT00470223 | ACTIVE_NOT_RECRUITING | Sarcoma |
UNICANCER |
2007-03 | PHASE3 |
| NCT00448357 | COMPLETED | Chronic Myeloproliferative Disorders; Leukemia; Lymphoma; Multiple Myeloma and Plasma Cell Neoplasm; Myelodysplastic Syndromes |
UNC Lineberger Comprehensive Cancer Center |
2005-10 | PHASE1; PHASE2 |
| NCT01941940 | COMPLETED | Rheumatoid Arthritis |
Hoffmann-La Roche |
2013-09-05 | PHASE3 |
| NCT02097264 | WITHDRAWN | Inflammation; Rheumatoid Arthritis |
Novo Nordisk A/S |
2014-09 | PHASE2 |
| NCT01483690 | TERMINATED | Acute Lymphoblastic Leukemia; Precursor B-Cell Lymphoblastic Leukemia; Precursor T-Cell Lymphoblastic Leukemia |
Therapeutic Advances in Childhood Leukemia Consortium |
2011-12 | PHASE1; PHASE2 |
| NCT01521923 | COMPLETED | Rheumatoid Arthritis |
UCB Pharma |
2012-01 | PHASE3 |
| NCT01999192 | TERMINATED | Rheumatoid Arthritis |
Biotest |
2013-10 | PHASE2 |
| NCT00450801 | COMPLETED | Lymphoma |
University of Miami |
2004-04 | PHASE2 |
| NCT01020734 | COMPLETED | Leukemia |
Asan Medical Center |
2011-05 | PHASE2 |
| NCT01927757 | TERMINATED | Moderate to Severe Rheumatoid Arthritis |
Amgen |
2013-05-06 | PHASE4 |
| NCT01403415 | COMPLETED | Childhood B Acute Lymphoblastic Leukemia; Childhood T Acute Lymphoblastic Leukemia; Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma; Recurrent Childhood Acute Lymphoblastic Leukemia; Recurrent Childhood Lymphoblastic Lymphoma |
National Cancer Institute (NCI) |
2011-09 | PHASE1 |
| NCT01443364 | COMPLETED | Rheumatoid Arthritis |
UCB Italy s.p.a. |
2011-12 | PHASE4 |
| NCT01855568 | COMPLETED | Ectopic Pregnancy |
CHA University |
2013-05 | PHASE3 |
| NCT01661140 | TERMINATED | Rheumatoid Arthritis |
Hoffmann-La Roche |
2012-09 | PHASE4 |
| NCT01619176 | COMPLETED | Rheumatoid Arthritis |
Chinese Academy of Sciences |
2012-10 | |
| NCT01851707 | COMPLETED | Rheumatoid Arthritis |
SecuraBio |
2013-04 | PHASE2 |
| NCT01238159 | COMPLETED | Extranodal NK-T-Cell Lymphoma, Nasal and Nasal-Type |
Samsung Medical Center |
2010-08 | PHASE2 |
| NCT01909427 | COMPLETED | Rheumatoid Arthritis |
Janssen Research & Development, LLC |
2013-06 | PHASE2 |
| NCT00651040 | COMPLETED | Polymyositis; Dermatomyositis |
Institute of Rheumatology, Prague |
2008-05 | PHASE3 |
| NCT01528163 | COMPLETED | Squamous Cell Carcinoma of the Head and Neck |
Cliniques universitaires Saint-Luc- Université Catholique de Louvain |
2012-02 | PHASE2 |
| NCT01936181 | COMPLETED | Rheumatoid Arthritis |
Samsung Bioepis Co., Ltd. |
2013-08 | PHASE3 |
| NCT01724931 | COMPLETED | Rheumatoid Arthritis |
Syntrix Biosystems, Inc. |
2013-02 | PHASE2 |
| NCT02079948 | WITHDRAWN | Inflammation; Aging |
University of Florida |
2014-02 | PHASE2 |
| NCT01741558 | UNKNOWN | Myocardial Infarction |
Instituto de Cardiologia do Rio Grande do Sul |
2013-04 | PHASE2 |
| NCT01749787 | COMPLETED | Arthritis, Rheumatoid |
Protalex, Inc. |
2012-11 | PHASE1 |
| NCT01518153 | TERMINATED | Leukemia; Lymphoma; Myeloma; Myeloproliferative Diseases |
M.D. Anderson Cancer Center |
2012-02 | PHASE2 |
| NCT00866307 | COMPLETED | Acute Lymphoblastic Leukemia; Adult B Acute Lymphoblastic Leukemia; Childhood B Acute Lymphoblastic Leukemia |
Children's Oncology Group |
2009-02-23 | PHASE1 |
| NCT02024334 | UNKNOWN | Juvenile Idiopathic Arthritis |
Mashhad University of Medical Sciences |
2013-06 | PHASE4 |
| NCT01724268 | UNKNOWN | RHEUMATOID ARTHRITIS |
Hamad Medical Corporation |
2012-05 | PHASE3 |
| NCT01067989 | TERMINATED | Chemotherapy; Breast Cancer, Metastatic |
HaEmek Medical Center, Israel |
2010-03 | PHASE2 |
| NCT01789255 | COMPLETED | Accelerated Phase Chronic Myelogenous Leukemia; Adult Acute Myeloid Leukemia in Remission; Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities; Adult Acute Myeloid Leukemia With Del(5q); Adult Acute Myeloid Leukemia With Inv(16)(p13;q22); Adult Acute Myeloid Leukemia With t(15;17)(q22;q12); Adult Acute Myeloid Leukemia With t(16;16)(p13;q22); Adult Acute Myeloid Leukemia With t(8;21)(q22;q22); Adult Grade III Lymphomatoid Granulomatosis; B-cell Chronic Lymphocytic Leukemia; Chronic Myelogenous Leukemia, BCR-ABL1 Positive; Chronic Myelomonocytic Leukemia; Chronic Phase Chronic Myelogenous Leukemia; Contiguous Stage II Adult Burkitt Lymphoma; Contiguous Stage II Adult Diffuse Large Cell Lymphoma; Contiguous Stage II Adult Diffuse Mixed Cell Lymphoma; Contiguous Stage II Adult Diffuse Small Cleaved Cell Lymphoma; Contiguous Stage II Adult Immunoblastic Large Cell Lymphoma; Contiguous Stage II Adult Lymphoblastic Lymphoma; Contiguous Stage II Grade 1 Follicular Lymphoma; Contiguous Stage II Grade 2 Follicular Lymphoma; Contiguous Stage II Grade 3 Follicular Lymphoma; Contiguous Stage II Mantle Cell Lymphoma; Contiguous Stage II Marginal Zone Lymphoma; Contiguous Stage II Small Lymphocytic Lymphoma; Cutaneous B-cell Non-Hodgkin Lymphoma; Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue; Graft Versus Host Disease; Intraocular Lymphoma; Myelodysplastic Syndrome With Isolated Del(5q); Myelodysplastic/Myeloproliferative Neoplasm, Unclassifiable; Nodal Marginal Zone B-cell Lymphoma; Noncontiguous Stage II Adult Burkitt Lymphoma; Noncontiguous Stage II Adult Diffuse Large Cell Lymphoma; Noncontiguous Stage II Adult Diffuse Mixed Cell Lymphoma; Noncontiguous Stage II Adult Diffuse Small Cleaved Cell Lymphoma; Noncontiguous Stage II Adult Immunoblastic Large Cell Lymphoma; Noncontiguous Stage II Adult Lymphoblastic Lymphoma; Noncontiguous Stage II Grade 1 Follicular Lymphoma; Noncontiguous Stage II Grade 2 Follicular Lymphoma; Noncontiguous Stage II Grade 3 Follicular Lymphoma; Noncontiguous Stage II Mantle Cell Lymphoma; Noncontiguous Stage II Marginal Zone Lymphoma; Noncontiguous Stage II Small Lymphocytic Lymphoma; Post-transplant Lymphoproliferative Disorder; Primary Central Nervous System Hodgkin Lymphoma; Primary Central Nervous System Non-Hodgkin Lymphoma; Recurrent Adult Acute Myeloid Leukemia; Recurrent Adult Burkitt Lymphoma; Recurrent Adult Diffuse Large Cell Lymphoma; Recurrent Adult Diffuse Mixed Cell Lymphoma; Recurrent Adult Diffuse Small Cleaved Cell Lymphoma; Recurrent Adult Grade III Lymphomatoid Granulomatosis; Recurrent Adult Hodgkin Lymphoma; Recurrent Adult Immunoblastic Large Cell Lymphoma; Recurrent Adult Lymphoblastic Lymphoma; Recurrent Grade 1 Follicular Lymphoma; Recurrent Grade 2 Follicular Lymphoma; Recurrent Grade 3 Follicular Lymphoma; Recurrent Mantle Cell Lymphoma; Recurrent Marginal Zone Lymphoma; Recurrent Small Lymphocytic Lymphoma; Refractory Anemia; Refractory Anemia With Excess Blasts; Refractory Anemia With Ringed Sideroblasts; Refractory Chronic Lymphocytic Leukemia; Refractory Cytopenia With Multilineage Dysplasia; Refractory Hairy Cell Leukemia; Relapsing Chronic Myelogenous Leukemia; Secondary Central Nervous System Hodgkin Lymphoma; Secondary Central Nervous System Non-Hodgkin Lymphoma; Small Intestine Lymphoma; Splenic Marginal Zone Lymphoma; Stage I Adult Burkitt Lymphoma; Stage I Adult Diffuse Large Cell Lymphoma; Stage I Adult Diffuse Mixed Cell Lymphoma; Stage I Adult Diffuse Small Cleaved Cell Lymphoma; Stage I Adult Hodgkin Lymphoma; Stage I Adult Immunoblastic Large Cell Lymphoma; Stage I Adult Lymphoblastic Lymphoma; Stage I Chronic Lymphocytic Leukemia; Stage I Grade 1 Follicular Lymphoma; Stage I Grade 2 Follicular Lymphoma; Stage I Grade 3 Follicular Lymphoma; Stage I Mantle Cell Lymphoma; Stage I Marginal Zone Lymphoma; Stage I Small Lymphocytic Lymphoma; Stage II Adult Hodgkin Lymphoma; Stage II Chronic Lymphocytic Leukemia; Stage III Adult Burkitt Lymphoma; Stage III Adult Diffuse Large Cell Lymphoma; Stage III Adult Diffuse Mixed Cell Lymphoma; Stage III Adult Diffuse Small Cleaved Cell Lymphoma; Stage III Adult Hodgkin Lymphoma; Stage III Adult Immunoblastic Large Cell Lymphoma; Stage III Adult Lymphoblastic Lymphoma; Stage III Chronic Lymphocytic Leukemia; Stage III Grade 1 Follicular Lymphoma; Stage III Grade 2 Follicular Lymphoma; Stage III Grade 3 Follicular Lymphoma; Stage III Mantle Cell Lymphoma; Stage III Marginal Zone Lymphoma; Stage IV Adult Burkitt Lymphoma; Stage IV Adult Diffuse Large Cell Lymphoma; Stage IV Adult Diffuse Mixed Cell Lymphoma; Stage IV Adult Diffuse Small Cleaved Cell Lymphoma; Stage IV Adult Hodgkin Lymphoma; Stage IV Adult Immunoblastic Large Cell Lymphoma; Stage IV Adult Lymphoblastic Lymphoma; Stage IV Chronic Lymphocytic Leukemia; Stage IV Grade 1 Follicular Lymphoma; Stage IV Grade 2 Follicular Lymphoma; Stage IV Grade 3 Follicular Lymphoma; Stage IV Mantle Cell Lymphoma; Stage IV Marginal Zone Lymphoma; Stage IV Small Lymphocytic Lymphoma; Testicular Lymphoma; Waldenström Macroglobulinemia |
National Cancer Institute (NCI) |
2013-06 | PHASE2 |
| NCT00317408 | UNKNOWN | Lymphoma |
European Inter-group Cooperation on Childhood and Adolescent Non Hodgkin Lymphoma |
2004-04 | |
| NCT00103285 | COMPLETED | Acute Lymphoblastic Leukemia; Childhood B Acute Lymphoblastic Leukemia |
Children's Oncology Group |
2005-04-11 | PHASE3 |
| NCT01850680 | COMPLETED | Rheumatoid Arthritis |
Sanofi |
2013-04 | PHASE1 |
| NCT01359943 | COMPLETED | Rheumatoid Arthritis |
Novartis Pharmaceuticals |
2011-10 | PHASE2 |
| NCT00720629 | TERMINATED | Graft Versus Host Disease |
H. Lee Moffitt Cancer Center and Research Institute |
2007-12 | PHASE2 |
| NCT01668680 | TERMINATED | Colorectal Cancer Metastatic |
HaEmek Medical Center, Israel |
2012-09 | PHASE2 |
| NCT01251614 | COMPLETED | Plaque Psoriasis |
AbbVie (prior sponsor, Abbott) |
2010-12 | PHASE3 |
| NCT01860690 | UNKNOWN | Ectopic Pregnancy |
Meir Medical Center |
2011-11 | PHASE4 |
| NCT01569152 | TERMINATED | Rheumatoid Arthritis (RA) |
Merck Sharp & Dohme LLC |
2012-05-22 | PHASE2 |
| NCT01142726 | COMPLETED | Rheumatoid Arthritis |
Bristol-Myers Squibb |
2010-12 | PHASE3 |
| NCT01317797 | COMPLETED | Rheumatoid Arthritis |
Takeda |
2011-03 | PHASE1 |
| NCT01984099 | COMPLETED | Hydatidiform Mole |
University of the Philippines |
2011-12 | PHASE3 |
| NCT00671658 | COMPLETED | Leukemia; Acute Lymphoblastic Leukemia |
M.D. Anderson Cancer Center |
2002-11 | PHASE2 |
| NCT02097745 | COMPLETED | Rheumatoid Arthritis |
Hoffmann-La Roche |
2004-06 | PHASE3 |
| NCT00992602 | COMPLETED | Central Nervous System Metastases; Leptomeningeal Metastases; Recurrent Breast Cancer; Stage IV Breast Cancer; Tumors Metastatic to Brain |
University of Washington |
2011-04 | PHASE2 |
| NCT00647049 | UNKNOWN | Primary Non Hodgkin Lymphoma of the Central Nervous System |
University Hospital Freiburg |
2007-01 | PHASE2 |
| NCT01639521 | WITHDRAWN | Anterior Urethral Cancer; Localized Transitional Cell Cancer of the Renal Pelvis and Ureter; Posterior Urethral Cancer; Recurrent Bladder Cancer; Recurrent Urethral Cancer; Regional Transitional Cell Cancer of the Renal Pelvis and Ureter; Stage III Bladder Cancer; Transitional Cell Carcinoma of the Bladder; Ureter Cancer; Urethral Cancer Associated With Invasive Bladder Cancer |
University of Southern California |
2013-05 | PHASE2 |
| NCT00422383 | COMPLETED | Rheumatoid Arthritis |
Hoffmann-La Roche |
2006-02 | PHASE3 |
| NCT00701129 | COMPLETED | Pompe Disease; Glycogen Storage Disease Type II |
Genzyme, a Sanofi Company |
2009-10 | PHASE4 |
| NCT01884636 | COMPLETED | Pharmacokinetics of Isavuconazole; Pharmacokinetics of Methotrexate; Pharmacokinetics of 7-hydroxymethotrexate; Healthy Subjects |
Astellas Pharma Global Development, Inc. |
2013-02 | PHASE1 |
| NCT01005914 | TERMINATED | Leukemia |
OHSU Knight Cancer Institute |
2009-06 | PHASE2 |
| NCT00513474 | COMPLETED | Chronic Myeloproliferative Disorders; Graft Versus Host Disease; Leukemia; Lymphoma; Multiple Myeloma and Plasma Cell Neoplasm; Myelodysplastic Syndromes; Myelodysplastic/Myeloproliferative Neoplasms |
Massachusetts General Hospital |
2008-01 | PHASE1 |
| NCT01323920 | COMPLETED | Leukemia; Lymphoma; Myelodysplastic Syndrome |
Dana-Farber Cancer Institute |
2011-05 | PHASE2 |
| NCT01612247 | UNKNOWN | Breast Cancer |
University of Vermont |
2011-02 | |
| NCT01382940 | COMPLETED | Rheumatoid Arthritis |
Hoffmann-La Roche |
2011-07-26 | PHASE4 |
| NCT01876004 | COMPLETED | Ectopic Pregnancy |
Federal University of São Paulo |
2011-09 | PHASE4 |
| NCT01567358 | COMPLETED | Rheumatoid Arthritis |
Nichi-Iko Pharmaceutical Co., Ltd. |
2012-02 | PHASE1 |
| NCT00669890 | TERMINATED | Acute Myeloid Leukemia; Juvenile Myelomonocytic Leukemia; Myelodysplastic Syndrome |
New York Medical College |
2004-05 | PHASE1 |
| NCT00803010 | COMPLETED | Acute Graft Versus Host Disease |
H. Lee Moffitt Cancer Center and Research Institute |
2008-09 | PHASE2 |
| NCT01197521 | COMPLETED | Rheumatoid Arthritis |
AstraZeneca |
2010-09 | PHASE3 |
| NCT00262925 | TERMINATED | Recurrent Adult Acute Lymphoblastic Leukemia |
National Cancer Institute (NCI) |
2006-06 | PHASE2 |
| NCT00754572 | COMPLETED | Rheumatoid Arthritis |
Hoffmann-La Roche |
2009-02 | PHASE3 |
| NCT01185301 | COMPLETED | Early Rheumatoid Arthritis |
AbbVie (prior sponsor, Abbott) |
2010-10 | PHASE3 |
| NCT01373151 | COMPLETED | Rheumatoid Arthritis |
CSL Behring |
2011-06 | PHASE2 |
| NCT00779142 | TERMINATED | Diabetic Macular Edema |
Wake Forest University |
2011-09 | |
| NCT01007435 | COMPLETED | Rheumatoid Arthritis |
Hoffmann-La Roche |
2009-10-31 | PHASE3 |
| NCT01083342 | COMPLETED | CNS Lymphoma |
Samsung Medical Center |
2010-01 | PHASE2 |
| NCT00322101 | COMPLETED | Acute Myeloid Leukemia With Multilineage Dysplasia Following Myelodysplastic Syndrome; Acute Myeloid Leukemia/Transient Myeloproliferative Disorder; Adult Acute Myeloid Leukemia in Remission; Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities; Adult Acute Myeloid Leukemia With Del(5q); Adult Acute Myeloid Leukemia With Inv(16)(p13;q22); Adult Acute Myeloid Leukemia With t(15;17)(q22;q12); Adult Acute Myeloid Leukemia With t(16;16)(p13;q22); Adult Acute Myeloid Leukemia With t(8;21)(q22;q22); Childhood Acute Myeloid Leukemia in Remission; Childhood Myelodysplastic Syndromes; de Novo Myelodysplastic Syndromes; Myelodysplastic Syndrome With Isolated Del(5q); Myelodysplastic/Myeloproliferative Neoplasm, Unclassifiable; Previously Treated Myelodysplastic Syndromes; Recurrent Adult Acute Myeloid Leukemia; Recurrent Childhood Acute Myeloid Leukemia; Secondary Acute Myeloid Leukemia; Secondary Myelodysplastic Syndromes |
Fred Hutchinson Cancer Center |
2006-01 | PHASE3 |
| NCT01188798 | COMPLETED | Acute Lymphoblastic Leukemia; Acute Myelocytic Leukemia; Chronic Myelocytic Leukemia; Hodgkin's Disease; Myelodysplastic Syndrome |
St. Jude Children's Research Hospital |
2010-09 | PHASE3 |
| NCT01359150 | COMPLETED | Rheumatoid Arthritis |
Pfizer |
2011-09 | PHASE2 |
| NCT00589563 | COMPLETED | Chronic Myeloproliferative Disorders; Graft Versus Host Disease; Infection; Leukemia; Lymphoma; Multiple Myeloma and Plasma Cell Neoplasm; Myelodysplastic Syndromes; Myelodysplastic/Myeloproliferative Neoplasms; Precancerous Condition; Secondary Myelofibrosis; Small Intestine Cancer |
City of Hope Medical Center |
2007-05 | PHASE2 |
| NCT00430118 | COMPLETED | Leukemia |
University Hospital Schleswig-Holstein |
2000-07 | PHASE3 |
| NCT00221325 | COMPLETED | Central Nervous System Lymphoma; Intraocular Lymphoma |
University of California, San Francisco |
2007-04 | PHASE1 |
| NCT00716248 | UNKNOWN | Rheumatoid Arthritis |
Saitama Medical University |
2007-01 | PHASE4 |
| NCT01253265 | COMPLETED | Rheumatoid Arthritis |
Eli Lilly and Company |
2010-05 | PHASE1 |
| NCT00184041 | COMPLETED | Acute Lymphoblastic Leukemia |
University of Southern California |
2004-07 | PHASE2 |
| NCT01248780 | COMPLETED | Rheumatoid Arthritis |
Centocor, Inc. |
2010-09 | PHASE3 |
| NCT00809172 | COMPLETED | Atopic Dermatitis |
Hospices Civils de Lyon |
2008-12 | PHASE3 |
| NCT00002766 | COMPLETED | Leukemia; Lymphoma |
Memorial Sloan Kettering Cancer Center |
1996-03 | PHASE3 |
| NCT01204138 | WITHDRAWN | Arthritis, Rheumatoid |
Stanford University |
2010-09 | PHASE2 |
| NCT00993317 | COMPLETED | Rheumatoid Arthritis |
Korea Otsuka Pharmaceutical Co., Ltd. |
2009-10 | PHASE3 |
| NCT00539838 | TERMINATED | Systemic Lupus Erythematosus |
Genentech, Inc. |
2007-12-19 | PHASE3 |
| NCT00976599 | COMPLETED | Rheumatoid Arthritis |
Pfizer |
2009-11 | PHASE2 |
| NCT01224041 | COMPLETED | Rheumatoid Arthritis |
Astellas Pharma Inc |
2009-08 | PHASE4 |
| NCT00989352 | UNKNOWN | Primary Non Hodgkin Lymphoma of the Central Nervous System |
University Hospital Freiburg |
2009-09 | PHASE2 |
| NCT01131910 | COMPLETED | Rheumatoid Arthritis; Exposed to TBE-virus; Immunosuppression |
Sormland County Council, Sweden |
2010-05 | PHASE2 |
| NCT00833053 | TERMINATED | Psoriasis |
Merck Sharp & Dohme LLC |
2009-10 | PHASE3 |
| NCT01211249 | COMPLETED | Rheumatoid Arthritis |
Lakefront Biotherapeutics NV |
2010-10 | PHASE2 |
| NCT00686868 | COMPLETED | Arthritis, Rheumatoid |
GlaxoSmithKline |
2008-06-13 | PHASE1 |
| NCT00853385 | COMPLETED | Rheumatoid Arthritis |
Pfizer |
2009-05 | PHASE3 |
| NCT00005047 | TERMINATED | Bladder Cancer |
SWOG Cancer Research Network |
1997-08 | PHASE3 |
| NCT00950989 | COMPLETED | Rheumatoid Arthritis |
Amgen |
2009-12-30 | PHASE2 |
| NCT00448201 | COMPLETED | Chronic Myeloproliferative Disorders; Leukemia; Lymphoma; Multiple Myeloma and Plasma Cell Neoplasm; Myelodysplastic Syndromes |
UNC Lineberger Comprehensive Cancer Center |
2011-01-07 | PHASE2 |
| NCT00360685 | COMPLETED | Mucositis; Graft-versus-host Disease |
H. Lee Moffitt Cancer Center and Research Institute |
2005-09 | |
| NCT01213017 | COMPLETED | Rheumatoid Arthritis |
Oklahoma Medical Research Foundation |
2010-09 | PHASE3 |
| NCT00392886 | UNKNOWN | Brain and Central Nervous System Tumors |
Children's Hospital Los Angeles |
2004-03 | PHASE3 |
| NCT00695188 | COMPLETED | Rheumatoid Arthritis |
Ludwig-Boltzmann Institut fuer Rheumatologie, Balneologie und Rehabilitation |
2008-05 | PHASE4 |
| NCT01303874 | COMPLETED | Rheumatoid Arthritis; Inflammatory Arthritis |
University of Leeds |
2006-09 | PHASE4 |
| NCT00673179 | TERMINATED | Osteosarcoma |
M.D. Anderson Cancer Center |
2008-05 | |
| NCT00334672 | UNKNOWN | Nonneoplastic Condition |
Children's Cancer and Leukaemia Group |
2006-03 | PHASE3 |
| NCT00489203 | COMPLETED | Hematopoietic/Lymphoid Cancer; Accelerated Phase Chronic Myelogenous Leukemia; Adult Acute Lymphoblastic Leukemia in Remission; Adult Acute Myeloid Leukemia in Remission; Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities; Adult Acute Myeloid Leukemia With Inv(16)(p13;q22); Adult Acute Myeloid Leukemia With t(15;17)(q22;q12); Adult Acute Myeloid Leukemia With t(16;16)(p13;q22); Adult Acute Myeloid Leukemia With t(8;21)(q22;q22); Atypical Chronic Myeloid Leukemia; Blastic Phase Chronic Myelogenous Leukemia; Childhood Acute Lymphoblastic Leukemia in Remission; Childhood Acute Myeloid Leukemia in Remission; Childhood Chronic Myelogenous Leukemia; Childhood Myelodysplastic Syndromes; Chronic Eosinophilic Leukemia; Chronic Myelomonocytic Leukemia; Chronic Neutrophilic Leukemia; Chronic Phase Chronic Myelogenous Leukemia; Contiguous Stage II Adult Burkitt Lymphoma; Contiguous Stage II Adult Diffuse Large Cell Lymphoma; Contiguous Stage II Adult Diffuse Mixed Cell Lymphoma; Contiguous Stage II Adult Diffuse Small Cleaved Cell Lymphoma; Contiguous Stage II Adult Immunoblastic Large Cell Lymphoma; Contiguous Stage II Adult Lymphoblastic Lymphoma; Contiguous Stage II Grade 1 Follicular Lymphoma; Contiguous Stage II Grade 2 Follicular Lymphoma; Contiguous Stage II Grade 3 Follicular Lymphoma; Contiguous Stage II Mantle Cell Lymphoma; Contiguous Stage II Marginal Zone Lymphoma; Contiguous Stage II Small Lymphocytic Lymphoma; de Novo Myelodysplastic Syndromes; Essential Thrombocythemia; Extramedullary Plasmacytoma; Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue; Graft Versus Host Disease; Isolated Plasmacytoma of Bone; Juvenile Myelomonocytic Leukemia; Meningeal Chronic Myelogenous Leukemia; Myelodysplastic/Myeloproliferative Disease, Unclassifiable; Nodal Marginal Zone B-cell Lymphoma; Noncontiguous Stage II Adult Burkitt Lymphoma; Noncontiguous Stage II Adult Diffuse Large Cell Lymphoma; Noncontiguous Stage II Adult Diffuse Small Cleaved Cell Lymphoma; Noncontiguous Stage II Adult Immunoblastic Large Cell Lymphoma; Noncontiguous Stage II Adult Lymphoblastic Lymphoma; Noncontiguous Stage II Grade 1 Follicular Lymphoma; Noncontiguous Stage II Grade 2 Follicular Lymphoma; Noncontiguous Stage II Grade 3 Follicular Lymphoma; Noncontiguous Stage II Mantle Cell Lymphoma; Noncontiguous Stage II Marginal Zone Lymphoma; Noncontiguous Stage II Small Lymphocytic Lymphoma; Previously Treated Myelodysplastic Syndromes; Primary Myelofibrosis; Recurrent Adult Acute Lymphoblastic Leukemia; Recurrent Adult Acute Myeloid Leukemia; Recurrent Adult Burkitt Lymphoma; Recurrent Adult Diffuse Large Cell Lymphoma; Recurrent Adult Diffuse Mixed Cell Lymphoma; Recurrent Adult Diffuse Small Cleaved Cell Lymphoma; Recurrent Adult Grade III Lymphomatoid Granulomatosis; Recurrent Adult Hodgkin Lymphoma; Recurrent Adult Lymphoblastic Lymphoma; Recurrent Adult T-cell Leukemia/Lymphoma; Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma; Recurrent Grade 1 Follicular Lymphoma; Recurrent Grade 2 Follicular Lymphoma; Recurrent Grade 3 Follicular Lymphoma; Recurrent Mantle Cell Lymphoma; Recurrent Marginal Zone Lymphoma; Recurrent Mycosis Fungoides/Sezary Syndrome; Recurrent Small Lymphocytic Lymphoma; Recurrent/Refractory Childhood Hodgkin Lymphoma; Refractory Chronic Lymphocytic Leukemia; Refractory Hairy Cell Leukemia; Relapsing Chronic Myelogenous Leukemia; Secondary Myelodysplastic Syndromes; Stage I Adult Burkitt Lymphoma; Stage I Adult Diffuse Large Cell Lymphoma; Stage I Adult Diffuse Mixed Cell Lymphoma; Stage I Adult Diffuse Small Cleaved Cell Lymphoma; Stage I Adult Hodgkin Lymphoma; Stage I Adult Immunoblastic Large Cell Lymphoma; Stage I Adult Lymphoblastic Lymphoma; Stage I Adult T-cell Leukemia/Lymphoma; Stage I Childhood Hodgkin Lymphoma; Stage I Chronic Lymphocytic Leukemia; Stage I Cutaneous T-cell Non-Hodgkin Lymphoma; Stage I Grade 1 Follicular Lymphoma; Stage I Grade 2 Follicular Lymphoma; Stage I Grade 3 Follicular Lymphoma; Stage I Mantle Cell Lymphoma; Stage I Marginal Zone Lymphoma; Stage I Multiple Myeloma; Stage I Mycosis Fungoides/Sezary Syndrome; Stage I Small Lymphocytic Lymphoma; Stage II Adult Hodgkin Lymphoma; Stage II Adult T-cell Leukemia/Lymphoma; Stage II Chronic Lymphocytic Leukemia; Stage II Cutaneous T-cell Non-Hodgkin Lymphoma; Stage II Multiple Myeloma; Stage II Mycosis Fungoides/Sezary Syndrome; Stage III Adult Burkitt Lymphoma; Stage III Adult Diffuse Large Cell Lymphoma; Stage III Adult Diffuse Mixed Cell Lymphoma; Stage III Adult Diffuse Small Cleaved Cell Lymphoma; Stage III Adult Hodgkin Lymphoma; Stage III Adult Immunoblastic Large Cell Lymphoma; Stage III Adult Lymphoblastic Lymphoma; Stage III Adult T-cell Leukemia/Lymphoma; Stage III Chronic Lymphocytic Leukemia; Stage III Cutaneous T-cell Non-Hodgkin Lymphoma; Stage III Grade 1 Follicular Lymphoma; Stage III Grade 2 Follicular Lymphoma; Stage III Grade 3 Follicular Lymphoma; Stage III Mantle Cell Lymphoma; Stage III Marginal Zone Lymphoma; Stage III Multiple Myeloma; Stage III Mycosis Fungoides/Sezary Syndrome; Stage III Small Lymphocytic Lymphoma; Stage IV Adult Burkitt Lymphoma; Stage IV Adult Diffuse Large Cell Lymphoma; Stage IV Adult Diffuse Mixed Cell Lymphoma; Stage IV Adult Diffuse Small Cleaved Cell Lymphoma; Stage IV Adult Hodgkin Lymphoma; Stage IV Adult Immunoblastic Large Cell Lymphoma; Stage IV Adult Lymphoblastic Lymphoma; Stage IV Adult T-cell Leukemia/Lymphoma; Stage IV Chronic Lymphocytic Leukemia; Stage IV Cutaneous T-cell Non-Hodgkin Lymphoma; Stage IV Grade 1 Follicular Lymphoma; Stage IV Grade 2 Follicular Lymphoma; Stage IV Grade 3 Follicular Lymphoma; Stage IV Marginal Zone Lymphoma; Stage IV Mycosis Fungoides/Sezary Syndrome; Stage IV Small Lymphocytic Lymphoma |
Fred Hutchinson Cancer Center |
2007-04 | PHASE2 |
| NCT00941707 | TERMINATED | Rheumatoid Arthritis |
Johnson & Johnson Pharmaceutical Research & Development, L.L.C. |
2010-02 | PHASE2 |
| NCT00443430 | COMPLETED | Juvenile Chronic Polyarthritis; Juvenile Idiopathic Arthritis; Juvenile Rheumatoid Arthritis |
Seattle Children's Hospital |
2007-05 | PHASE4 |
| NCT00555048 | TERMINATED | Graft Versus Host Disease; Leukemia; Myelodysplastic Syndromes; Myelodysplastic/Myeloproliferative Diseases |
Fred Hutchinson Cancer Center |
2007-09 | PHASE1; PHASE2 |
| NCT01007175 | COMPLETED | Rheumatoid Arthritis |
Ablynx, a Sanofi company |
2009-11 | PHASE1; PHASE2 |
| NCT00503594 | UNKNOWN | Lymphoma |
Assistance Publique - Hôpitaux de Paris |
2007-07 | PHASE2 |
| NCT00787761 | COMPLETED | Myeloproliferative Disorders; Kidney Cancer; Leukemia; Lymphoma; Multiple Myeloma and Plasma Cell Neoplasm; Myelodysplastic Syndromes; Myelodysplastic/Myeloproliferative Diseases |
Northside Hospital, Inc. |
2007-04 | PHASE2 |
| NCT00369226 | COMPLETED | Hematologic Malignancies |
Dana-Farber Cancer Institute |
2006-08 | PHASE1; PHASE2 |
| NCT00450983 | TERMINATED | Graft Versus Host Disease; Leukemia; Myelodysplastic Syndromes |
Fred Hutchinson Cancer Center |
2006-12 | PHASE2 |
| NCT00928200 | TERMINATED | Relapsed Acute Lymphoblastic Leukemia; Allergy to PEG e.Coli Asparaginase; Allergy to Native e.Coli Asparaginase |
Therapeutic Advances in Childhood Leukemia Consortium |
2009-04-13 | PHASE1 |
| NCT00609739 | TERMINATED | Leukemia |
Masonic Cancer Center, University of Minnesota |
1999-06 | PHASE1; PHASE2 |
| NCT01117129 | TERMINATED | Rheumatoid Arthritis |
Hoffmann-La Roche |
2010-04 | PHASE4 |
| NCT01010503 | COMPLETED | Rheumatoid Arthritis |
Hoffmann-La Roche |
2009-06 | PHASE4 |
| NCT00687648 | UNKNOWN | Breast Cancer |
National Cancer Centre, Singapore |
2008-05 | PHASE2 |
| NCT00579878 | COMPLETED | Rheumatoid Arthritis |
University of Nebraska |
2001-03-27 | PHASE3 |
| NCT00278278 | UNKNOWN | Brain and Central Nervous System Tumors |
German Society for Pediatric Oncology and Hematology GPOH gGmbH |
2003-09 | PHASE3 |
| NCT02660684 | COMPLETED | Graft Versus Host Disease |
Astellas Pharma Korea, Inc. |
2008-02 | PHASE4 |
| NCT01173120 | COMPLETED | Rheumatoid Arthritis (RA) |
Bristol-Myers Squibb |
2009-11 | PHASE3 |
| NCT00509678 | COMPLETED | Psoriatic Arthritis |
Swedish Medical Center |
2006-12 | PHASE1 |
| NCT00354107 | TERMINATED | Anaplastic Large Cell Lymphoma; Recurrent Childhood Anaplastic Large Cell Lymphoma |
National Cancer Institute (NCI) |
2007-01 | PHASE1; PHASE2 |
| NCT00578305 | COMPLETED | Rheumatoid Arthritis |
Hoffmann-La Roche |
2007-11 | PHASE3 |
| NCT00989703 | COMPLETED | Healthy |
Lakefront Biotherapeutics NV |
2009-09 | PHASE1 |
| NCT00679731 | COMPLETED | Psoriasis |
AbbVie (prior sponsor, Abbott) |
2008-04 | PHASE3 |
| NCT00673920 | TERMINATED | Rheumatoid Arthritis |
Genentech, Inc. |
2008-04-24 | PHASE3 |
| NCT00424502 | COMPLETED | Rheumatoid Arthritis |
Hoffmann-La Roche |
2007-01 | PHASE4 |
| NCT00595413 | COMPLETED | Rheumatoid Arthritis |
EMD Serono |
2007-09 | PHASE2 |
| NCT00525213 | COMPLETED | Rheumatoid Arthritis |
OxyPharma |
2007-10 | PHASE2 |
| NCT00634504 | COMPLETED | Osteosarcoma; Leukemia; Lymphoma |
BTG International Inc. |
2008-05 | PHASE1 |
| NCT00550355 | COMPLETED | Arthritis, Rheumatoid |
Pfizer |
2007-08 | PHASE1 |
| NCT00665925 | COMPLETED | Rheumatoid Arthritis |
Rigel Pharmaceuticals |
2008-05 | PHASE2 |
| NCT00354393 | COMPLETED | Malignant Mesothelioma |
The Cleveland Clinic |
2002-08 | PHASE2 |
| NCT00913432 | COMPLETED | Rheumatoid Arthritis |
AB Science |
2007-03 | PHASE2 |
| NCT01026519 | COMPLETED | Rheumatoid Arthritis |
Regeneron Pharmaceuticals |
2008-09 | PHASE1 |
| NCT00847886 | COMPLETED | Rheumatoid Arthritis |
Lexicon Pharmaceuticals |
2009-02 | PHASE1 |
| NCT00621036 | WITHDRAWN | Brain and Central Nervous System Tumors; Lymphoma; Lymphoproliferative Disorder; Small Intestine Cancer |
University of Texas Southwestern Medical Center |
2007-10-19 | PHASE2 |
| NCT00547521 | COMPLETED | Rheumatoid Arthritis (RA) |
Bristol-Myers Squibb |
2007-12 | PHASE3 |
| NCT00487825 | COMPLETED | Rheumatoid Arthritis |
Novartis |
2007-03 | PHASE2 |
| NCT00189488 | COMPLETED | Graft Versus Host Disease; Hematologic Malignancies |
Swedish Orphan Biovitrum |
2005-12 | PHASE2 |
| NCT00620685 | COMPLETED | Arthritis, Rheumatoid |
Pfizer |
2008-03 | PHASE2 |
| NCT00299104 | COMPLETED | Rheumatoid Arthritis |
Genentech, Inc. |
2006-01 | PHASE3 |
| NCT00603512 | COMPLETED | Arthritis, Rheumatoid |
Pfizer |
2008-01 | PHASE2 |
| NCT00424346 | COMPLETED | Rheumatoid Arthritis |
Novartis |
2006-11 | PHASE2 |
| NCT00136084 | COMPLETED | Leukemia, Myelocytic, Acute |
St. Jude Children's Research Hospital |
2002-08 | PHASE3 |
| NCT00409838 | COMPLETED | Rheumatoid Arthritis |
Bristol-Myers Squibb |
2007-04 | PHASE3 |
| NCT00348413 | COMPLETED | Graves Ophthalmopathy |
Singapore National Eye Centre |
2003-06 | |
| NCT00299130 | COMPLETED | Rheumatoid Arthritis |
Genentech, Inc. |
2005-10 | PHASE3 |
| NCT00521430 | COMPLETED | Leukemia; Lymphoma; Multiple Myeloma and Plasma Cell Neoplasm; Myelodysplastic Syndromes; Nonmalignant Neoplasm; Unspecified Adult Solid Tumor, Protocol Specific |
Asan Medical Center |
2004-04 | |
| NCT00732875 | COMPLETED | Arthritis, Rheumatoid |
Merck Sharp & Dohme LLC |
2006-08 | PHASE3 |
| NCT00152178 | COMPLETED | Breast Cancer |
Taiho Pharmaceutical Co., Ltd. |
1996-07 | PHASE3 |
| NCT00074269 | TERMINATED | Breast Cancer |
University of California, San Diego |
2003-07 | PHASE2 |
| NCT00425321 | COMPLETED | Rheumatoid Arthritis |
Johnson & Johnson Pharmaceutical Research & Development, L.L.C. |
2006-12 | PHASE2 |
| NCT00174707 | COMPLETED | Breast Neoplasms |
Sanofi |
1997-12 | PHASE3 |
| NCT00424294 | TERMINATED | Arthritis, Rheumatoid |
Pfizer |
2006-06 | PHASE2 |
| NCT00005945 | COMPLETED | Leukemia |
Children's Oncology Group |
2000-06 | PHASE3 |
| NCT00041132 | COMPLETED | Lymphoma |
SWOG Cancer Research Network |
2002-09 | PHASE2 |
| NCT00326339 | COMPLETED | Rheumatoid Arthritis |
Rigel Pharmaceuticals |
2006-08 | PHASE2 |
| NCT00161239 | TERMINATED | T-Cell Lymphoma |
University of Medicine and Dentistry of New Jersey |
2005-02 | |
| NCT00210314 | COMPLETED | Lymphoma, B Cell |
International Extranodal Lymphoma Study Group (IELSG) |
2003-07 | PHASE2 |
| NCT00446784 | COMPLETED | Arthritis, Rheumatoid |
Pfizer |
2007-04 | PHASE1 |
| NCT00005585 | COMPLETED | Leukemia |
Children's Oncology Group |
2000-04 | PHASE3 |
| NCT00280917 | COMPLETED | Rheumatoid Arthritis |
Can-Fite BioPharma |
2006-06 | PHASE2 |
| NCT00119301 | COMPLETED | Sarcoma |
Memorial Sloan Kettering Cancer Center |
2005-04 | PHASE1 |
| NCT00002542 | COMPLETED | Breast Cancer |
NCIC Clinical Trials Group |
1993-07-20 | PHASE3 |
| NCT00301860 | TERMINATED | Leukemia; Lymphoma |
University of California, San Francisco |
2003-01 | |
| NCT00058461 | TERMINATED | B-cell Childhood Acute Lymphoblastic Leukemia; Childhood Burkitt Lymphoma; Childhood Diffuse Large Cell Lymphoma; Childhood Immunoblastic Large Cell Lymphoma; L3 Childhood Acute Lymphoblastic Leukemia; Recurrent Childhood Acute Lymphoblastic Leukemia; Recurrent Childhood Large Cell Lymphoma; Recurrent Childhood Lymphoblastic Lymphoma; Recurrent Childhood Small Noncleaved Cell Lymphoma |
National Cancer Institute (NCI) |
2003-11 | PHASE2 |
| NCT00003593 | COMPLETED | Leukemia; Myelodysplastic Syndromes; Myelodysplastic/Myeloproliferative Neoplasms |
Children's Oncology Group |
1999-06 | PHASE3 |
| NCT00002463 | COMPLETED | Brain and Central Nervous System Tumors |
M.D. Anderson Cancer Center |
1989-02 | PHASE2 |
| NCT00019864 | TERMINATED | Cardiac Toxicity; Sarcoma |
National Cancer Institute (NCI) |
2000-03 | PHASE2 |
| NCT00020943 | COMPLETED | Lymphoma |
Alliance for Clinical Trials in Oncology |
2001-06 | PHASE2 |
| NCT00141830 | COMPLETED | Rheumatoid Arthritis |
Wyeth is now a wholly owned subsidiary of Pfizer |
2005-08 | PHASE2 |
| NCT00215046 | COMPLETED | Intraluminal Pulmonary Vein Stenosis |
Boston Children's Hospital |
2000-03 | PHASE2 |
| NCT00089349 | COMPLETED | Recurrent Childhood Acute Lymphoblastic Leukemia |
National Cancer Institute (NCI) |
2004-07 | PHASE2 |
| NCT01745055 | COMPLETED | Rheumatoid Arthritis |
Pfizer |
2005-04 | PHASE1 |
| NCT00579644 | COMPLETED | Rheumatoid Arthritis |
University of Nebraska |
2001-03-28 | PHASE3 |
| NCT00235820 | COMPLETED | Psoriasis |
Abbott |
2005-07 | PHASE3 |
| NCT00049569 | COMPLETED | L1 Childhood Acute Lymphoblastic Leukemia; L2 Childhood Acute Lymphoblastic Leukemia; Non-T, Non-B Childhood Acute Lymphoblastic Leukemia; Recurrent Childhood Acute Lymphoblastic Leukemia; T-cell Childhood Acute Lymphoblastic Leukemia |
National Cancer Institute (NCI) |
2003-01 | |
| NCT01225874 | COMPLETED | Leukemia |
Children's Oncology Group |
1999-12 | |
| NCT00416819 | COMPLETED | Brain and Central Nervous System Tumors; Lymphoma |
University of California, San Francisco |
2003-09 | |
| NCT00419809 | COMPLETED | Arthritis, Rheumatoid |
GlaxoSmithKline |
2005-05 | PHASE1 |
| NCT00023998 | COMPLETED | Metastatic Osteosarcoma |
National Cancer Institute (NCI) |
2001-07 | PHASE2 |
| NCT00076206 | TERMINATED | Rheumatoid Arthritis |
Wyeth is now a wholly owned subsidiary of Pfizer |
2003-12 | PHASE2 |
| NCT00005596 | COMPLETED | Leukemia |
Children's Oncology Group |
2000-04 | PHASE3 |
| NCT00003632 | COMPLETED | Lymphoma |
Memorial Sloan Kettering Cancer Center |
1998-09 | PHASE2 |
| NCT00003868 | COMPLETED | Leukemia |
Fred Hutchinson Cancer Center |
1999-02 | PHASE2 |
| NCT00005802 | COMPLETED | Leukemia |
Fred Hutchinson Cancer Center |
1999-06 | PHASE1; PHASE2 |
| NCT00083759 | TERMINATED | Rheumatoid Arthritis |
Biogen |
2004-05 | PHASE2 |
| NCT00207714 | COMPLETED | Rheumatoid Arthritis |
Centocor, Inc. |
2003-11 | PHASE2 |
| NCT00002970 | COMPLETED | Recurrent Childhood Acute Lymphoblastic Leukemia; Recurrent Childhood Lymphoblastic Lymphoma; T-cell Childhood Acute Lymphoblastic Leukemia |
National Cancer Institute (NCI) |
1997-06 | PHASE2 |
| NCT00193011 | COMPLETED | Breast Cancer |
SCRI Development Innovations, LLC |
2002-03 | PHASE3 |
| NCT00187122 | COMPLETED | Lymphoblastic Lymphoma |
St. Jude Children's Research Hospital |
1993-03 | |
| NCT00794898 | COMPLETED | Arthritis, Rheumatoid |
Merck Sharp & Dohme LLC |
2003-07-01 | PHASE4 |
| NCT00002494 | COMPLETED | Leukemia; Lymphoma |
Alliance for Clinical Trials in Oncology |
1992-05 | PHASE2 |
| NCT00002700 | COMPLETED | Leukemia; Lymphoma |
European Organisation for Research and Treatment of Cancer - EORTC |
1995-08 | PHASE3 |
| NCT00005866 | COMPLETED | Leukemia; Myelodysplastic Syndromes |
SWOG Cancer Research Network |
2000-02 | PHASE3 |
| NCT00037102 | COMPLETED | Multiple Sclerosis |
MidAmerica Neuroscience Research Foundation at Rowe Neurology Institute |
2001-07 | PHASE4 |
| NCT00002809 | COMPLETED | Leukemia; Myelodysplastic Syndromes; Myelodysplastic/Myeloproliferative Diseases |
Temple University |
1996-08 | PHASE2 |
| NCT00002657 | COMPLETED | Lymphoma; Multiple Myeloma and Plasma Cell Neoplasm |
SWOG Cancer Research Network |
1995-05 | PHASE2 |
| NCT00003056 | TERMINATED | Leukemia; Lymphoma; Graft Versus Host Disease |
Baxalta now part of Shire |
1997-04-01 | PHASE3 |
| NCT00199095 | COMPLETED | Adult Acute Lymphocytic Leukemia |
Goethe University |
1997-02 | PHASE4 |
| NCT00002792 | COMPLETED | Chronic Myeloproliferative Disorders; Leukemia; Myelodysplastic/Myeloproliferative Diseases |
Fred Hutchinson Cancer Center |
1996-06 | PHASE2 |
| NCT00006747 | COMPLETED | Graft Versus Host Disease; Lymphoma |
Alliance for Clinical Trials in Oncology |
2000-11 | PHASE2 |
| NCT00002471 | COMPLETED | Leukemia; Lymphoma |
Memorial Sloan Kettering Cancer Center |
1990-02 | PHASE2 |
| NCT00006054 | TERMINATED | Immunologic Deficiency Syndromes; Chediak-Higashi Syndrome; Common Variable Immunodeficiency; Graft Versus Host Disease; X-Linked Lymphoproliferative Syndrome; Familial Erythrophagocytic Lymphohistiocytosis; Hemophagocytic Lymphohistiocytosis; X-linked Agammaglobulinemia; Wiskott-Aldrich Syndrome; Chronic Granulomatous Disease; X-linked Hyper IgM Syndrome; Severe Combined Immunodeficiency; Leukocyte Adhesion Deficiency Syndrome; Virus-Associated Hemophagocytic Syndrome |
Fairview University Medical Center |
2000-03 | |
| NCT00037115 | WITHDRAWN | Demyelinating Disorders; Multiple Sclerosis; Optic Neuritis; Myelitis; Neuritis |
MidAmerica Neuroscience Research Foundation at Rowe Neurology Institute |
2002-05 | PHASE4 |
| NCT00002816 | COMPLETED | Leukemia |
Children's Oncology Group |
1996-12 | PHASE3 |
| NCT00187005 | TERMINATED | Acute Lymphoblastic Leukemia |
St. Jude Children's Research Hospital |
1998-07 | PHASE3 |
| NCT00003061 | COMPLETED | Lymphoma |
European Organisation for Research and Treatment of Cancer - EORTC |
1997-07 | PHASE2 |
| NCT00002665 | COMPLETED | Leukemia; Neutropenia; Thrombocytopenia |
SWOG Cancer Research Network |
1995-07 | PHASE2 |
| NCT00002552 | COMPLETED | Lymphoma; Multiple Myeloma and Plasma Cell Neoplasm |
Barbara Ann Karmanos Cancer Institute |
1993-10 | PHASE2 |
| NCT00002961 | TERMINATED | Leukemia |
Children's Hospital of Philadelphia |
1995-10 | PHASE3 |
| NCT00006451 | WITHDRAWN | Graft Versus Host Disease; Leukemia; Lymphoma |
Masonic Cancer Center, University of Minnesota |
1996-04 | PHASE3 |
| NCT00002618 | COMPLETED | Lymphoma |
Children's Oncology Group |
1994-12 | PHASE3 |
| NCT00003776 | COMPLETED | Sarcoma |
Memorial Sloan Kettering Cancer Center |
1998-12 | PHASE2 |
| NCT01177371 | COMPLETED | Accelerated Phase Chronic Myelogenous Leukemia; Adult Acute Lymphoblastic Leukemia in Remission; Adult Acute Megakaryoblastic Leukemia (M7); Adult Acute Monoblastic Leukemia (M5a); Adult Acute Monocytic Leukemia (M5b); Adult Acute Myeloblastic Leukemia With Maturation (M2); Adult Acute Myeloblastic Leukemia Without Maturation (M1); Adult Acute Myeloid Leukemia in Remission; Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities; Adult Acute Myeloid Leukemia With Del(5q); Adult Acute Myeloid Leukemia With Inv(16)(p13;q22); Adult Acute Myeloid Leukemia With T(15;17)(q22;q12); Adult Acute Myeloid Leukemia With T(16;16)(p13;q22); Adult Acute Myeloid Leukemia With T(8;21)(q22;q22); Adult Acute Myelomonocytic Leukemia (M4); Adult Acute Promyelocytic Leukemia (M3); Adult Erythroleukemia (M6a); Adult Nasal Type Extranodal NK/T-cell Lymphoma; Adult Pure Erythroid Leukemia (M6b); Anaplastic Large Cell Lymphoma; Angioimmunoblastic T-cell Lymphoma; Burkitt Lymphoma; Childhood Acute Erythroleukemia (M6); Childhood Acute Lymphoblastic Leukemia in Remission; Childhood Acute Megakaryocytic Leukemia (M7); Childhood Acute Monoblastic Leukemia (M5a); Childhood Acute Monocytic Leukemia (M5b); Childhood Acute Myeloblastic Leukemia With Maturation (M2); Childhood Acute Myeloblastic Leukemia Without Maturation (M1); Childhood Acute Myeloid Leukemia in Remission; Childhood Acute Myelomonocytic Leukemia (M4); Childhood Acute Promyelocytic Leukemia (M3); Childhood Chronic Myelogenous Leukemia; Childhood Myelodysplastic Syndromes; Chronic Phase Chronic Myelogenous Leukemia; Cutaneous B-cell Non-Hodgkin Lymphoma; De Novo Myelodysplastic Syndromes; Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue; Hepatosplenic T-cell Lymphoma; Intraocular Lymphoma; Nodal Marginal Zone B-cell Lymphoma; Peripheral T-Cell Lymphoma; Post-transplant Lymphoproliferative Disorder; Previously Treated Myelodysplastic Syndromes; Recurrent Adult Acute Lymphoblastic Leukemia; Recurrent Adult Acute Myeloid Leukemia; Recurrent Adult Burkitt Lymphoma; Recurrent Adult Diffuse Large Cell Lymphoma; Recurrent Adult Diffuse Mixed Cell Lymphoma; Recurrent Adult Diffuse Small Cleaved Cell Lymphoma; Recurrent Adult Grade III Lymphomatoid Granulomatosis; Recurrent Adult Hodgkin Lymphoma; Recurrent Adult Immunoblastic Large Cell Lymphoma; Recurrent Adult Lymphoblastic Lymphoma; Recurrent Adult Non-Hodgkin Lymphoma; Recurrent Adult T-cell Leukemia/Lymphoma; Recurrent Childhood Acute Lymphoblastic Leukemia; Recurrent Childhood Acute Myeloid Leukemia; Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma; Recurrent Grade 1 Follicular Lymphoma; Recurrent Grade 2 Follicular Lymphoma; Recurrent Grade 3 Follicular Lymphoma; Recurrent Mantle Cell Lymphoma; Recurrent Marginal Zone Lymphoma; Recurrent Mycosis Fungoides/Sezary Syndrome; Recurrent Small Lymphocytic Lymphoma; Refractory Multiple Myeloma; Relapsing Chronic Myelogenous Leukemia; Secondary Myelodysplastic Syndromes; Small Intestine Lymphoma; Splenic Marginal Zone Lymphoma; Testicular Lymphoma; Waldenstrom Macroglobulinemia |
Case Comprehensive Cancer Center |
1988-03 | PHASE2 |
| NCT00002554 | COMPLETED | Leukemia |
Fred Hutchinson Cancer Center |
1993-11 | PHASE2 |
| NCT00199069 | COMPLETED | Adult Acute Lymphocytic Leukemia |
Goethe University |
1993-04 | PHASE4 |
| NCT00041613 | UNKNOWN | Carcinoma, Squamous Cell |
Introgen Therapeutics |
PHASE3 | |
| NCT00001298 | COMPLETED | Kidney Diseases |
National Cancer Institute (NCI) |
1992-03 | PHASE1 |
| NCT00920608 | WITHDRAWN | Rheumatoid Arthritis |
AstraZeneca |
2009-05 | PHASE1 |
| NCT00243750 | UNKNOWN | Ankylosing Spondylitis |
Charite University, Berlin, Germany |
2003-09 | PHASE2 |
| NCT00002582 | COMPLETED | Breast Cancer |
Institute of Cancer Research, United Kingdom |
1993-06 | PHASE3 |
| NCT00365001 | COMPLETED | Rheumatoid Arthritis |
Hoffmann-La Roche |
PHASE1 | |
| NCT00004567 | COMPLETED | Vasculitis; Wegener's Granulomatosis |
National Institute of Allergy and Infectious Diseases (NIAID) |
2000-02 | PHASE2 |
| NCT00002580 | COMPLETED | Breast Cancer |
Scottish Cancer Therapy Network |
1993-06 | PHASE3 |
| NCT00012311 | UNKNOWN | Breast Cancer |
Herbert Irving Comprehensive Cancer Center |
2000-01 | PHASE2 |
| NCT00002456 | COMPLETED | Graft Versus Host Disease; Leukemia; Lymphoma |
Fred Hutchinson Cancer Center |
1986-05 | PHASE3 |
| NCT00291915 | UNKNOWN | Rheumatoid Arthritis; Arthritis |
Goupe d'Etudes et de Recherche Clinique En Rhumatologie |
2004-05 | PHASE4 |
| NCT00470522 | COMPLETED | Systemic Lupus Erythematosus |
University Health Network, Toronto |
1995-06 | PHASE3 |
| NCT00003577 | COMPLETED | Breast Cancer |
University Hospital Birmingham |
1996-03 | PHASE3 |
| NCT00296257 | TERMINATED | Rheumatoid Arthritis (RA) |
Dainippon Sumitomo Pharma Europe LTd. |
2006-02 | PHASE2 |
| NCT00439283 | COMPLETED | Ankylosing Spondylitis |
Association de Recherche Clinique en Rhumatologie |
2003-04 | PHASE3 |
| NCT00077870 | COMPLETED | Rheumatoid Arthritis |
Genentech, Inc. |
2004-02 | PHASE1; PHASE2 |
| NCT00002701 | UNKNOWN | Leukemia |
European Organisation for Research and Treatment of Cancer - EORTC |
1995-10 | PHASE3 |
| NCT00246064 | COMPLETED | Arthritis, Rheumatoid |
Centocor Ortho Biotech Services, L.L.C. |
2001-12 | PHASE4 |
| NCT00209859 | COMPLETED | Rheumatoid Arthritis |
Hvidovre University Hospital |
1998-10 | PHASE4 |
| NCT00455286 | UNKNOWN | Primary Central Nervous System Lymphoma |
National Health Research Institutes, Taiwan |
2006-11 | PHASE2 |
| NCT00024050 | COMPLETED | Leukemia; Myelodysplastic Syndromes |
Fred Hutchinson Cancer Center |
2001-02 | PHASE2 |
| NCT00443950 | COMPLETED | Arthritis, Rheumatoid |
Wyeth is now a wholly owned subsidiary of Pfizer |
2006-06 | PHASE3 |
| NCT00105976 | COMPLETED | Rheumatoid Arthritis |
Merrimack Pharmaceuticals |
2005-02 | PHASE2 |
| NCT00276757 | COMPLETED | Childhood Langerhans Cell Histiocytosis |
Histiocyte Society |
2001-04 | |
| NCT00005854 | COMPLETED | Leukemia; Lymphoma; Multiple Myeloma and Plasma Cell Neoplasm; Myelodysplastic Syndromes |
Fred Hutchinson Cancer Center |
1999-12 | PHASE2 |
| NCT00236028 | COMPLETED | Rheumatoid Arthritis |
Centocor, Inc. |
PHASE3 | |
| NCT00002499 | UNKNOWN | Leukemia |
Grupo Argentino de Tratamiento de la Leucemia Aguda |
1990-01 | PHASE2; PHASE3 |
| NCT00081055 | WITHDRAWN | Graft Versus Host Disease; Leukemia; Myelodysplastic Syndromes |
Mesoblast International Sàrl |
PHASE2 | |
| NCT00018954 | COMPLETED | Leukemia; Lymphoma |
National Institutes of Health Clinical Center (CC) |
1992-10 | PHASE2 |
| NCT00029523 | COMPLETED | Meningeal Neoplasms |
Pacira Pharmaceuticals, Inc |
2001-04 | PHASE4 |
| NCT00000834 | COMPLETED | HIV Infections |
National Institute of Allergy and Infectious Diseases (NIAID) |
PHASE1 | |
| NCT00141934 | COMPLETED | Rheumatoid Arthritis |
Sosei |
2005-08 | PHASE2 |
| NCT00002531 | UNKNOWN | Leukemia |
Johann Wolfgang Goethe University Hospital |
1993-01 | PHASE2 |
| NCT00669812 | UNKNOWN | Lymphoma; Small Intestine Cancer |
Cancer Research UK |
2008-02 | PHASE2 |
| NCT00069017 | COMPLETED | Rheumatoid Arthritis |
MedImmune LLC |
2003-09 | PHASE2 |
(data from https://clinicaltrials.gov, updated on 2023-02-21)
Check the
Methotrexate
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
Mechanism and Biochemical Profile
Appendix RUO and cGMP Quality Standards
| Quality Dimension | RUO (Research Use Only) | cGMP (Current Good Manufacturing Practice) |
|---|---|---|
| Clinical Applicability | Prohibited in human clinical trials or medical diagnostics. | Mandatory for human clinical trials (Phase I–III) and therapies. |
| Regulatory Status | Non-regulated grade; exempt from drug manufacturing laws. | Legally enforced by health authorities (e.g., FDA, EMA, NMPA). |
| Facility Environment | Unclassified analytical or research laboratories. | Validated Cleanrooms (ISO Class 5–8) with continuous monitoring. |
| Quality Control | Basic purity and activity testing. | Rigorous safety release testing (Sterility, Endotoxin, Mycoplasma). |
| Process Validation | Basic equipment calibration; no process validation required. | Full qualification (IQ/OQ/PQ) and complete batch records. |
| Quality Assurance | Vendor self-declared without required formal QMS. | Mandatory QA/QC unit, Change Control, CAPA, and vendor audits. |
| Regulatory Impact | High risk of IND rejection if used as a critical raw material. | Required for IND/NDA filings, supported by Drug Master Files (DMF). |
Footnotes
Regulatory Note: Governed by FDA (21 CFR Parts 210/211/312), EMA (EudraLex Vol 4), ICH Guidelines (E6/Q7/Q9/Q10), and compendial standards (USP <71>/<85>/<1043>).
- Methotrexate Mechanism of Action: Dihydrofolate Reductase Inhibition in Lymphocyte Research
- Methotrexate Working Concentration | Cell Culture | Treatment
- Methotrexate Solubility in DMSO
- Methotrexate Storage
- Methotrexate Stability
- Methotrexate Combination Database
- Methotrexate Molecular Weight
- Methotrexate SMILES
- Methotrexate CAS Number
- Methotrexate Chemical Structure (2D and 3D)
- Methotrexate IC50 for Cell-based and Cell-free Assays
- Methotrexate Cayman (13960)? Try a better option.
- Methotrexate MedChemExpress (HY-14519)? Try a better option.
- Methotrexate Sigma (PHR1396)? Try a better option.
- Methotrexate APExBIO (A4347)? Try a better option.
- Methotrexate SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.