PRMT Chemicals

Cat.No.	Product Name	Information	Product Use Citations	Product Validations
S8479	LLY-284	LLY-284 is the diastereomer of LLY-283, which is a potent and selective SAM-competitive chemical probe for PRMT5. This compound is much less active than LLY-283 and can be used as a negative control for it.
S0184	XY1	XY1 is an inactive, close analog of SGC707 that can be used as the negative control for SGC707. SGC707 is a potent, selective and cell-active allosteric inhibitor of protein arginine methyltransferase 3 (PRMT3) with IC50 and Kd of 31 nM and 53 nM, respectively.