MDM2/MDMX Activator

Cat.No. Product Name Information Product Use Citations Product Validations
S2341 (-)-Parthenolide (-)-Parthenolide, an inhibitor of the Nuclear Factor-κB Pathway, specifically depletes HDAC1 protein without affecting other class I/II HDACs; Also promotes the ubiquitination of MDM2 and activates p53 cellular functions.
J Adv Res, 2025, S2090-1232(25)00353-4
Biomed Pharmacother, 2025, 188:118183
Cell Death Discov, 2025, 11(1):286
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