Glucosidase Inhibitors

Cat.No.	Product Name	Information	Product Use Citations
S9378	4',5-Dihydroxyflavone	4',5-Dihydroxyflavone inhibits soybean LOX-1 and yeast α-glucosidase.	Medical University of Bialystok, 2022, Vol. 79 No. 6 pp. 835-840, 2022
S4101	Voglibose	Voglibose (AO 128) is an N-substituted derivative of valiolamine, excellent inhibitory activity against α-glucosidases and its action against hyperglycemia and various disorders caused by hyperglycemia.	G3 (Bethesda), 2020, 4;10(5):1585-1597
E7012	Conduritol B epoxide	Conduritol B epoxide is an irreversible covalently bound inhibitor of Gcase. It can be used in the research of Neuronopathic Gaucher disease (nGD).
E0477	N-Caffeoyl O-methyltyramine	N-Caffeoyl O-methyltyramine is a class of alkaloid isolated from Cuscuta reflexa with strong inhibitory activity against α-glucosidase with IC50 of 103.58 μM.
S0553	Butyl isobutyl phthalate	Butyl isobutyl phthalate (BIP), isolated from the rhizoid of Laminaria japonica, is a non-competitive inhibitor of α-glucosidase with IC50 of 38 μM. Butyl isobutyl phthalate displays a significant hypoglycemic effect and has the potential for diabetes treatment.
E7646	Castanospermine	Castanospermine is a natural alkaloid that can be extracted from black beans or the Moreton Bay chestnut tree (Castanospermum australae). Castanospermine is an α/ β-glucosidase inhibitor. Castanospermine has anti-inflammatory, antiviral replication and anti-metastatic effects on prostate cancer. Castanospermine can be used as an immunosuppressant to prevent transplant rejection.
S3796	Rebaudioside A	Rebaudioside A (Stevia Extract, Reb A, Glycoside A3, Stevioside A3), an natural sweetening ingredient extracted from the stevia leaf, is used in powder or liquid form to heighten sweetening intensity and improve taste. This compound is a steviol glycoside, α-glucosidase inhibitor with IC50 of 35.01 μg/ml.can inhibit ATP-sensitive K+-channels.
S9445	Ginkgolic Acid (C13:0)	Ginkgolic Acid (C13:0), a natural anticariogenic agent in Ginkgo biloba L., exhibits antimicrobial activity against S. mutans and suppresses the specific virulence factors associated with its cariogenicity. This compound is a potent sumoylation inhibitor and reported to inhibit histone acetylation transferase (HAT).