E3 Ligase Activator

Cat.No. Product Name Information Product Use Citations Product Validations
S2678 NSC 207895 NSC 207895 (XI-006) suppresses MDMX with IC50 of 2.5 μM, leading to enhanced p53 stabilization/activation and DNA damage, and also regulates MDM2, an E3 ligase.
Oncotarget, November 17, 2020, 4224-4242
PLoS One, January 26, 2024, e0295629
PLoS One, 2024, e0295629
Verified customer review of NSC 207895