ATF/CREB & c-Fos/c-Jun

Other JAK/STAT Related Inhibitors

JAK STAT Pim

Cat.No.	Product Name	Information	Product Use Citations	Product Validations
S1204	Melatonin	Melatonin is a MT receptor agonist, used as a dietary supplement. This compound is a selective ATF-6 inhibitor and downregulates COX-2. It enhances mitophagy and regulates the homeostasis of apoptosis and autophagy.	Antioxidants (Basel), 2025, 14(5)528 Sci Rep, 2025, 15(1):8451 Biochem Biophys Res Commun, 2025, 760:151706
E2653	JNK-IN-7	JNK-IN-7 is a strong JNK inhibitor with IC50 of 1.5, 2 and 0.7 nM for JNK1, JNK2 and JNK3, which inhibits phosphorylation of c-Jun, direct substrate of JNK kinase.

Cat.No.

Product Name

Information

Product Use Citations

Product Validations

S1204

Melatonin

Melatonin is a MT receptor agonist, used as a dietary supplement. This compound is a selective ATF-6 inhibitor and downregulates COX-2. It enhances mitophagy and regulates the homeostasis of apoptosis and autophagy.

Antioxidants (Basel), 2025, 14(5)528

Sci Rep, 2025, 15(1):8451

Biochem Biophys Res Commun, 2025, 760:151706

E2653

JNK-IN-7

JNK-IN-7 is a strong JNK inhibitor with IC50 of 1.5, 2 and 0.7 nM for JNK1, JNK2 and JNK3, which inhibits phosphorylation of c-Jun, direct substrate of JNK kinase.