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THR Agonists

Cat.No. Product Name Information Product Use Citations Product Validations
S6663 MGL-3196 (Resmetirom) Resmetirom (MGL-3196, VIA-3196) is a liver-directed, orally active, selective thyroid hormone receptor β(THR-β) agonist with an EC50 of 0.21 μM,shows 28-fold selective for THR-β over THR-α in a functional assay.
Int J Mol Sci, 2023, 24(6)5843
Front Chem, 2022, 10:888587
S3747 Levothyroxine (L-Thyroxine) sodium Levothyroxine (L-Thyroxine) sodium is the major hormone derived from the thyroid gland. It is the agonist of Thyroid hormone receptor alpha and beta.
Cancer Cell, 2025, 43(4):776-796.e14
E2877 dextrothyroxine sodium Dextrothyroxine (D-T4) sodium, a sodium salt of D-T4, is a laevorotatory isomer of thyroxine used for thyroid related studies.
S0343 Eprotirome (KB2115) Eprotirome (KB2115), a liver-selective agonist of thyroid hormone receptor (TR), is investigated for the potential treatment of dyslipidemias and obesity.
E5811New ALG-055009 ALG-055009 is a potent and selective agonist of thyroid hormone receptor beta (THR-β), used for treating MASH (Metabolic Dysfunction-Associated Steatohepatitis).