NOS Modulator

Featured Inhibitors
Inhibitors (23)
Modulator (1)
Chemicals (2)
Agonist (1)
Activators (2)

Cat.No.	Product Name	Information	Product Use Citations	Product Validations
S6962	TPEN	TPEN (TPEDA) is a specific cell-permeable heavy metal chelator that induces apoptosis in NB4 cells via negatively regulating intracellular NO and Zn²⁺ signaling. This compound may be a potential therapeutic strategy for APL (acute promyelocytic leukemia). It induces DNA damage and increases intracellular ROS production and also inhibits cell proliferation.	J Cachexia Sarcopenia Muscle, 2025, 16(2):e13771 J Biol Chem, 2025, 301(10):110653 Biomaterials, 2021, 271:120720

Cat.No.

Product Name

Information

Product Use Citations

Product Validations

S6962

TPEN

TPEN (TPEDA) is a specific cell-permeable heavy metal chelator that induces apoptosis in NB4 cells via negatively regulating intracellular NO and Zn²⁺ signaling. This compound may be a potential therapeutic strategy for APL (acute promyelocytic leukemia). It induces DNA damage and increases intracellular ROS production and also inhibits cell proliferation.

J Cachexia Sarcopenia Muscle, 2025, 16(2):e13771

J Biol Chem, 2025, 301(10):110653

Biomaterials, 2021, 271:120720