New JAK Inhibitors

Catalog No.	Product Name	Information
E1828	BHV-8000	BHV-8000 (TLL-041) is a first-in-class, oral, brain-penetrant, dual TYK2/JAK1 selective inhibitor that targets the JAK-STAT pathway signaling implicated in the mixed inflammatory response driving progression of many neuroinflammatory and neurodegenerative conditions, including Parkinson's disease, Alzheimer's disease, and multiple sclerosis.
S9814	BMS-986202	BMS‑986202 is a potent, selective and orally active inhibitor of TYK2 that binds to the TYK2 pseudokinase domain (JH2) with an IC50 of 0.19 nM and a Ki of 0.02 nM.
S3521	Golidocitinib(AZD4205)	Golidocitinib (AZD4205) (Compound 21) is a highly selective and potent inhibitor of Janus kinase 1 (JAK1), with an IC50 of 0.07 μM for JAK1 and much weaker inhibition of JAK2 (IC50 > 15 μM). It also exhibits potent antitumor effects in NSCLC xenograft models in preclinical studies.
F2644	Phospho-JAK1 (Tyr1034/1035)/JAK2 (Tyr1007/1008) Antibody [L3G19]
≡ All JAK Inhibitors