New JAK Inhibitors
| Cat.No. | Product Name | Information |
|---|---|---|
| S7812 | Itacitinib (INCB39110) | Itacitinib(INCB39110) is an orally bioavailable inhibitor of Janus-associated kinase 1 (JAK1) with potential antineoplastic activity. |
| S8538 | PF-06651600 | PF-06651600 is a potent and irreversible JAK3-selective inhibitor with an IC50 of 33.1 nM but without activity (IC50 > 10 000 nM) against JAK1, JAK2, and TYK2. |
| S8541 | FM-381 | FM-381 is a JAK3 specific reversible covalent inhibitor with IC50 of 127 pM for JAK3 and demonstrates 400-, 2,700- and 3,600-fold selectivity over JAK1, JAK2, and TYK2, respectively. |
| ≡ All JAK Inhibitors | ||
