| A2680 |
Ozanezumab (Anti-RTN4 / NOGO) |
Ozanezumab (Anti-RTN4 / NOGO) is a monoclonal antibody targeting Nogo-A (neurite outgrowth inhibitor A). It can be used in amyotrophic lateral sclerosis (ALS) and multiple sclerosis research. MW :150 KD. |
Human IgG1 |
| A2936 |
Modotuximab (Anti-ERBB1 / EGFR / HER1) |
Modotuximab (Anti-ERBB1 / EGFR / HER1) is a recombinant immunoglobulin G1 (IgG1) monoclonal antibody directed against the epidermal growth factor receptor (EGFR) with potential antineoplastic activity. MW: 146.6 KD. |
Human IgG1 |
| A2681 |
Brontictuzumab (Anti-NOTCH1) |
Brontictuzumab (Anti-NOTCH1) is a monoclonal antibody that targets Notch1 signal. It inhibits tumor cell proliferation and can be used in the research of leukemia and lymphoma. MW :150 KD. |
Human IgG2SA |
| A2937 |
Anti-ICOS / CD278 (MEDI-570) |
Anti-ICOS/CD278 (MEDI-570) is a Fc-optimized humanized immunoglobulin (Ig) G1 monoclonal antibody (MoAb) directed against the inducible T-cell co-stimulator (ICOS, CD278) with potential immune checkpoint inhibitory and antineoplastic activities. It has the potential to treat non-Hodgkin lymphomas. MW: 146.82 KD. |
Human IgG1 |
| A2682 |
Vesencumab (Anti-NRP1 / VEGF165R / CD304) |
Vesencumab (Anti-NRP1 / VEGF165R / CD304) is an IG1 antibody targeting neuropilin-1 (NRP-1). It has anti-angiogenic and anti-neoplastic activities and can be used in the research of metastatic solid tumors, including ovarian cancer and Diabetic macular edema (DME). MW :150 KD. |
Human IgG1 |
| A2938 |
Anti-IFNg (AMG 811) |
Anti-IFNg (AMG 811) is a human monoclonal antibody (IgG1 isotype) that selectively targets human IFNgamma 7. It has potential to treat systemic lupus erythematosus (SLE). MW: 144.36 KD. |
Human IgG1 |
| A2683 |
Tavolixizumab (Anti-TNFRSF4 / OX40 / CD134) |
Tavolixizumab (Anti-TNFRSF4 / OX40 / CD134) is a human monoclonal antibody targeting TNFRSF4 (TNF receptor superfamily member 4) and OX40. It can be used in cancer immunology research. MW :146.36 KD. |
Human IgG1 |
| A2939 |
Ligelizumab (Anti-IgE) |
Ligelizumab (anti-IgE) is a humanized high-affinity monoclonal anti-IgE antibody with the potential to be used in research on chronic spontaneous urticarial. MW: 146.6 KD. |
Human IgG1 |
| A2684 |
Anti-PDGFC / VEGFE |
Anti-PDGFC / VEGFE is a monoclonal antibody targeting PDGF-CC. It can be used in the research of cancer, fibrosis and neuropathologies. MW :145.9 KD. |
Human IgG1 |
| A2940 |
Talizumab (Anti-IgE) |
Talizumab (anti-IgE) is a humanized monoclonal antibody against immunoglobulin E (IgE) with the potential to treat food allergies. MW: 146.56 KD. |
Human IgG1 |
| A2941 |
Naptumomab (Anti-TPBG) |
Naptumomab (Anti-TPBG) is a monoclonal antibody directed towards the tumor-associated oncofetal trophoblast glycoprotein antigen 5T4 with immunomodulating and antineoplastic activities. MW: 145.18 KD. |
Human IgG1 |
| A2686 |
Anti-PSCA (AGS-1C4D4) |
Anti-PSCA (AGS-1C4D4) is a fully human IgG1k monoclonal antibody directed against the human prostate stem cell antigen (PSCA). Anti-PSCA inhibits tumor formation and metastasis in orthotopic models of pancreatic cancer. MW : 145.42 kD. |
Human IgG1 |
| A2942 |
Figitumumab (Anti-IGF1R / CD221) |
Figitumumab (Anti-IGF1R / CD221) is a human monoclonal antibody directed against the insulin-like growth factor type I receptor (IGF1R) with potential antineoplastic activity. Figitumumab prevents IGF1 from binding to IGF1R with an IC50 of 1.8 nM. MW: 146.0 KD. |
Human IgG1 |
| A2687 |
Anti-PVRIG (GSK4381562) |
Anti-PVRIG (GSK4381562) is a human immunoglobulin G1 (IgG1) monoclonal antibody directed against poliovirus receptor-related immunoglobulin (PVRIG; PVR Related Immunoglobulin Domain Containing Protein; CD112R), with potential immune checkpoint inhibitory and antineoplastic activities. MW : 150 kD. |
Human IgG1 |
| A2688 |
Anti-AGER / RAGE (XT-M4) |
Anti-AGER / RAGE (XT-M4) is a humanized anti-RAGE antibody with potential to treat acute and chronic inflammatory conditions. MW: 145.14 KD. |
Human IgG1 |
| A2944 |
Nimotuzumab (Anti-ERBB1 / EGFR / HER1) |
Nimotuzumab (Anti-ERBB1 / EGFR / HER1) is a humanized monoclonal antibody directed against the epidermal growth factor receptor (EGFR) with potential antineoplastic activity. MW: 147.58 KD. |
Human IgG1 |
| A2689 |
Anti-RSPO1 |
Anti-RSPO1 is a monoclonal antibodies against R-spondin1 gene (RSPO1) with potential anti-tumor activity . MW: 150 KD. |
Human IgG1 |
| A2945 |
Anti-IGF2 (DX-2647) |
Anti-IGF2 (DX-2647) is a human monoclonal antibody against insulin-like growth factor-II (IGF-II) with anti-tumor and anti-proliferative activities. MW: 145.78 KD. |
Human IgG1 |
| A2690 |
Setrusumab (Anti-SOST / Sclerostin) |
Setrusumab (Anti-SOST / Sclerostin) is a fully humanized monoclonal antibody directed against sclerostin. Setrusumab effectively improves bone strength and has the potential to be used in the research of Osteogenesis Imperfecta (OI). MW :143.44 kD. |
Human IgG2SA |
| A2946 |
Anti-IL-10 (BT-063) |
Anti-IL-10 (BT-063) is a human monoclonal antibody directed against the human interleukin 10 (IL-10). It has the potential to be used in the treatment of systemic lupus erythematosus (SLE). MW: 145.74 KD. |
Human IgG1 |